Basic Information:

  VIRBase ID:  

HHID00096358

  Virus:  

Human immunodeficiency virus (HIV)

  Host:  

Homo sapiens

  Confidence Score:  

0.5711

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-320a-3p:  MIMAT0000510          CRISPLD2:  NM_031476     

      *It may take a few minutes to display results.

Interactor Information:

	Interactor1	Interactor2
Symbol	hsa-miR-320a-3p	CRISPLD2
miRBase Accession/Entrez ID	MIMAT0000510	83716
Organism	Homo sapiens	Homo sapiens
Category	miRNA	mRNA
Alias	-	CRISP11//LCRISP2//LGL1

ncRNA SNP information:

Resource	Symbol	SNP ID	SNP Position	Ref/Alt
miRNASNP-v3	hsa-miR-320a-3p	rs1276783280 chr8:22244983    T/C rs1304651256 chr8:22244976    C/A rs1335522641 chr8:22244984    C/G rs1342806696 chr8:22244985    A/T rs1380599305 chr8:22244977    G/A rs376090584 chr8:22244982    C/T rs745462427 chr8:22244996    T/A rs745462427 chr8:22244996    T/C rs778232802 chr8:22244988    C/A rs778232802 chr8:22244988    C/T rs1029283088 chr8:22244995    T/C rs1272164828 chr8:22244990    A/G rs1295910991 chr8:22244991    G/C rs1311220991 chr8:22244994    T/C

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	CRISPLD2	chr16:84917156(+) A-I      intronic chr16:84917187(+) A-I      intronic chr16:84917189(+) A-I      intronic chr16:84917197(+) A-I      intronic chr16:84926155(+) A-I      intronic chr16:84926176(+) A-I      intronic chr16:84928472(+) A-I      intronic chr16:84917154(+) A-I      intronic chr16:84926108(+) A-I      intronic chr16:84926116(+) A-I      intronic chr16:84926117(+) A-I      intronic chr16:84926132(+) A-I      intronic chr16:84928479(+) A-I      intronic chr16:84928498(+) A-I      intronic chr16:84928539(+) A-I      intronic chr16:84928540(+) A-I      intronic chr16:84928552(+) A-I      intronic chr16:84928553(+) A-I      intronic chr16:84938654(+) A-I      intronic chr16:84938632(+) A-I      intronic chr16:84938625(+) A-I      intronic chr16:84938111(+) A-I      intronic chr16:84938105(+) A-I      intronic chr16:84938102(+) A-I      intronic chr16:84938099(+) A-I      intronic chr16:84938097(+) A-I      intronic chr16:84938075(+) A-I      intronic chr16:84938039(+) A-I      intronic chr16:84938031(+) A-I      intronic chr16:84938014(+) A-I      intronic chr16:84938012(+) A-I      intronic chr16:84937961(+) A-I      intronic chr16:84936073(+) A-I      intronic chr16:84936066(+) A-I      intronic chr16:84863713(+) A-I      intronic chr16:84936064(+) A-I      intronic chr16:84936063(+) A-I      intronic chr16:84936054(+) A-I      intronic chr16:84936053(+) A-I      intronic chr16:84936031(+) A-I      intronic chr16:84935436(+) A-I      intronic chr16:84934525(+) A-I      intronic chr16:84934509(+) A-I      intronic chr16:84934506(+) A-I      intronic chr16:84934419(+) A-I      intronic chr16:84932719(+) A-I      intronic chr16:84932712(+) A-I      intronic chr16:84932681(+) A-I      intronic chr16:84932664(+) A-I      intronic chr16:84932648(+) A-I      intronic chr16:84920286(+) A-I      intronic chr16:84920282(+) A-I      intronic chr16:84920279(+) A-I      intronic chr16:84920275(+) A-I      intronic chr16:84920253(+) A-I      intronic chr16:84920252(+) A-I      intronic chr16:84920245(+) A-I      intronic chr16:84920233(+) A-I      intronic chr16:84920228(+) A-I      intronic chr16:84942420(+) A-I      3'UTR chr16:84942434(+) A-I      3'UTR chr16:84942443(+) A-I      3'UTR chr16:84920222(+) A-I      intronic chr16:84910288(+) A-I      intronic chr16:84910284(+) A-I      intronic chr16:84910279(+) A-I      intronic chr16:84910278(+) A-I      intronic chr16:84909308(+) A-I      intronic chr16:84909263(+) A-I      intronic chr16:84942450(+) A-I      3'UTR chr16:84942475(+) A-I      3'UTR chr16:84942478(+) A-I      3'UTR chr16:84904543(+) A-I      intronic chr16:84904541(+) A-I      intronic chr16:84904535(+) A-I      intronic chr16:84904533(+) A-I      intronic chr16:84904508(+) A-I      intronic chr16:84904487(+) A-I      intronic chr16:84904456(+) A-I      intronic chr16:84897504(+) A-I      intronic chr16:84897453(+) A-I      intronic chr16:84897445(+) A-I      intronic chr16:84897435(+) A-I      intronic chr16:84897410(+) A-I      intronic chr16:84897397(+) A-I      intronic chr16:84897356(+) A-I      intronic chr16:84897337(+) A-I      intronic chr16:84880103(+) A-I      intronic chr16:84880049(+) A-I      intronic chr16:84863824(+) A-I      intronic chr16:84863813(+) A-I      intronic chr16:84863807(+) A-I      intronic chr16:84863801(+) A-I      intronic chr16:84863799(+) A-I      intronic chr16:84863773(+) A-I      intronic chr16:84863771(+) A-I      intronic chr16:84863728(+) A-I      intronic chr16:84863714(+) A-I      intronic chr16:84863709(+) A-I      intronic chr16:84904928(+) A-I      intronic chr16:84904966(+) A-I      intronic chr16:84905060(+) A-I      intronic chr16:84905287(+) A-I      intronic chr16:84905392(+) A-I      intronic chr16:84908709(+) A-I      intronic chr16:84908717(+) A-I      intronic chr16:84909226(+) A-I      intronic chr16:84909232(+) A-I      intronic chr16:84909243(+) A-I      intronic chr16:84909280(+) A-I      intronic chr16:84909302(+) A-I      intronic chr16:84909352(+) A-I      intronic chr16:84909406(+) A-I      intronic chr16:84909434(+) A-I      intronic chr16:84909879(+) A-I      intronic chr16:84910057(+) A-I      intronic chr16:84910192(+) A-I      intronic chr16:84910203(+) A-I      intronic chr16:84910213(+) A-I      intronic chr16:84910215(+) A-I      intronic chr16:84910268(+) A-I      intronic chr16:84910314(+) A-I      intronic chr16:84910319(+) A-I      intronic chr16:84911775(+) A-I      intronic chr16:84911787(+) A-I      intronic chr16:84911790(+) A-I      intronic chr16:84913068(+) A-I      intronic chr16:84913069(+) A-I      intronic chr16:84919464(+) A-I      intronic chr16:84919499(+) A-I      intronic chr16:84920157(+) A-I      intronic chr16:84920158(+) A-I      intronic chr16:84920174(+) A-I      intronic chr16:84920219(+) A-I      intronic chr16:84920239(+) A-I      intronic chr16:84920243(+) A-I      intronic chr16:84920258(+) A-I      intronic chr16:84920264(+) A-I      intronic chr16:84920265(+) A-I      intronic chr16:84920266(+) A-I      intronic chr16:84920270(+) A-I      intronic chr16:84920271(+) A-I      intronic chr16:84920386(+) A-I      intronic chr16:84921219(+) A-I      intronic chr16:84921339(+) A-I      intronic chr16:84921950(+) A-I      intronic chr16:84921954(+) A-I      intronic chr16:84921958(+) A-I      intronic chr16:84921975(+) A-I      intronic chr16:84923709(+) A-I      intronic chr16:84923808(+) A-I      intronic chr16:84923818(+) A-I      intronic chr16:84923822(+) A-I      intronic chr16:84926405(+) A-I      intronic chr16:84926426(+) A-I      intronic chr16:84926443(+) A-I      intronic chr16:84926527(+) A-I      intronic chr16:84926552(+) A-I      intronic chr16:84930830(+) A-I      intronic chr16:84930840(+) A-I      intronic chr16:84931278(+) A-I      intronic chr16:84931316(+) A-I      intronic chr16:84931323(+) A-I      intronic chr16:84931408(+) A-I      intronic chr16:84880984(+) A-I      intronic chr16:84931497(+) A-I      intronic chr16:84932656(+) A-I      intronic chr16:84932702(+) A-I      intronic chr16:84932717(+) A-I      intronic chr16:84934448(+) A-I      intronic chr16:84934462(+) A-I      intronic chr16:84935121(+) A-I      intronic chr16:84935164(+) A-I      intronic chr16:84935293(+) A-I      intronic chr16:84935480(+) A-I      intronic chr16:84935500(+) A-I      intronic chr16:84935501(+) A-I      intronic chr16:84935525(+) A-I      intronic chr16:84935529(+) A-I      intronic chr16:84936058(+) A-I      intronic chr16:84936122(+) A-I      intronic chr16:84936157(+) A-I      intronic chr16:84936403(+) A-I      intronic chr16:84936518(+) A-I      intronic chr16:84936540(+) A-I      intronic chr16:84936544(+) A-I      intronic chr16:84936553(+) A-I      intronic chr16:84936571(+) A-I      intronic chr16:84936648(+) A-I      intronic chr16:84936654(+) A-I      intronic chr16:84937087(+) A-I      intronic chr16:84937109(+) A-I      intronic chr16:84937119(+) A-I      intronic chr16:84937139(+) A-I      intronic chr16:84937140(+) A-I      intronic chr16:84937153(+) A-I      intronic chr16:84937155(+) A-I      intronic chr16:84937935(+) A-I      intronic chr16:84937957(+) A-I      intronic chr16:84937976(+) A-I      intronic chr16:84938122(+) A-I      intronic chr16:84938139(+) A-I      intronic chr16:84938160(+) A-I      intronic chr16:84938609(+) A-I      intronic chr16:84938613(+) A-I      intronic chr16:84938629(+) A-I      intronic chr16:84938667(+) A-I      intronic chr16:84938677(+) A-I      intronic chr16:84938703(+) A-I      intronic chr16:84938716(+) A-I      intronic chr16:84939029(+) A-I      intronic chr16:84939080(+) A-I      intronic chr16:84939134(+) A-I      intronic chr16:84939194(+) A-I      intronic chr16:84939390(+) A-I      intronic chr16:84939409(+) A-I      intronic chr16:84939416(+) A-I      intronic chr16:84939433(+) A-I      intronic chr16:84939455(+) A-I      intronic chr16:84939457(+) A-I      intronic chr16:84939513(+) A-I      intronic chr16:84939590(+) A-I      intronic chr16:84858619(+) A-I      intronic chr16:84862613(+) A-I      intronic chr16:84863742(+) A-I      intronic chr16:84863781(+) A-I      intronic chr16:84868796(+) A-I      intronic chr16:84874169(+) A-I      intronic chr16:84874193(+) A-I      intronic chr16:84874294(+) A-I      intronic chr16:84879938(+) A-I      intronic chr16:84879939(+) A-I      intronic chr16:84880025(+) A-I      intronic chr16:84880033(+) A-I      intronic chr16:84931485(+) A-I      intronic chr16:84880060(+) A-I      intronic chr16:84880062(+) A-I      intronic chr16:84881054(+) A-I      intronic chr16:84881070(+) A-I      intronic chr16:84881072(+) A-I      intronic chr16:84881074(+) A-I      intronic chr16:84881080(+) A-I      intronic chr16:84881100(+) A-I      intronic chr16:84881107(+) A-I      intronic chr16:84881110(+) A-I      intronic chr16:84881163(+) A-I      intronic chr16:84881198(+) A-I      intronic chr16:84895344(+) A-I      intronic chr16:84896015(+) A-I      intronic chr16:84897327(+) A-I      intronic chr16:84897351(+) A-I      intronic chr16:84897388(+) A-I      intronic chr16:84897389(+) A-I      intronic chr16:84897395(+) A-I      intronic chr16:84897399(+) A-I      intronic chr16:84897518(+) A-I      intronic chr16:84897520(+) A-I      intronic chr16:84897528(+) A-I      intronic chr16:84897542(+) A-I      intronic chr16:84897551(+) A-I      intronic chr16:84897554(+) A-I      intronic chr16:84904469(+) A-I      intronic chr16:84904906(+) A-I      intronic chr16:84938043(+) A-I      intronic chr16:84897484(+) A-I      intronic chr16:84935517(+) A-I      intronic chr16:84936927(+) A-I      intronic chr16:84937958(+) A-I      intronic chr16:84920404(+) A-I      intronic chr16:84895481(+) A-I      intronic chr16:84904606(+) A-I      intronic chr16:84932611(+) A-I      intronic chr16:84897419(+) A-I      intronic chr16:84861195(+) A-I      intronic chr16:84904998(+) A-I      intronic chr16:84936095(+) A-I      intronic chr16:84935944(+) A-I      intronic chr16:84936626(+) A-I      intronic chr16:84936013(+) A-I      intronic chr16:84905275(+) A-I      intronic chr16:84895480(+) A-I      intronic chr16:84910380(+) A-I      intronic chr16:84913242(+) A-I      intronic chr16:84929783(+) A-I      intronic chr16:84910170(+) A-I      intronic chr16:84905258(+) A-I      intronic chr16:84904449(+) A-I      intronic chr16:84930937(+) A-I      intronic chr16:84880004(+) A-I      intronic chr16:84937036(+) A-I      intronic chr16:84900089(+) A-I      intronic chr16:84911200(+) A-I      intronic chr16:84897385(+) A-I      intronic chr16:84924538(+) A-I      intronic chr16:84904984(+) A-I      intronic chr16:84934510(+) A-I      intronic chr16:84879933(+) A-I      intronic chr16:84896074(+) A-I      intronic chr16:84862587(+) A-I      intronic chr16:84908817(+) A-I      intronic chr16:84938766(+) A-I      intronic chr16:84881206(+) A-I      intronic chr16:84862570(+) A-I      intronic chr16:84868745(+) A-I      intronic chr16:84935961(+) A-I      intronic chr16:84939171(+) A-I      intronic chr16:84934552(+) A-I      intronic chr16:84930964(+) A-I      intronic chr16:84934495(+) A-I      intronic chr16:84904907(+) A-I      intronic chr16:84904000(+) A-I      intronic chr16:84931303(+) A-I      intronic chr16:84934493(+) A-I      intronic chr16:84926357(+) A-I      intronic chr16:84930979(+) A-I      intronic chr16:84898971(+) A-I      intronic chr16:84910347(+) A-I      intronic chr16:84936596(+) A-I      intronic chr16:84879988(+) A-I      intronic chr16:84859439(+) A-I      intronic chr16:84935486(+) A-I      intronic chr16:84932598(+) A-I      intronic chr16:84921938(+) A-I      intronic chr16:84924245(+) A-I      intronic chr16:84938806(+) A-I      intronic chr16:84937201(+) A-I      intronic chr16:84939146(+) A-I      intronic chr16:84926435(+) A-I      intronic chr16:84910348(+) A-I      intronic chr16:84881178(+) A-I      intronic chr16:84910058(+) A-I      intronic chr16:84904197(+) A-I      intronic chr16:84897414(+) A-I      intronic chr16:84862582(+) A-I      intronic chr16:84910301(+) A-I      intronic chr16:84935589(+) A-I      intronic chr16:84939144(+) A-I      intronic chr16:84881003(+) A-I      intronic chr16:84935541(+) A-I      intronic chr16:84939445(+) A-I      intronic chr16:84904065(+) A-I      intronic chr16:84930799(+) A-I      intronic chr16:84936118(+) A-I      intronic chr16:84936105(+) A-I      intronic chr16:84881214(+) A-I      intronic chr16:84904915(+) A-I      intronic chr16:84895446(+) A-I      intronic chr16:84910028(+) A-I      intronic chr16:84904073(+) A-I      intronic chr16:84935539(+) A-I      intronic chr16:84897578(+) A-I      intronic chr16:84938817(+) A-I      intronic chr16:84909440(+) A-I      intronic chr16:84921868(+) A-I      intronic chr16:84930848(+) A-I      intronic chr16:84881002(+) A-I      intronic chr16:84880122(+) A-I      intronic chr16:84864046(+) A-I      intronic chr16:84936479(+) A-I      intronic chr16:84934545(+) A-I      intronic chr16:84930885(+) A-I      intronic chr16:84897454(+) A-I      intronic chr16:84939525(+) A-I      intronic chr16:84863747(+) A-I      intronic chr16:84916039(+) A-I      intronic chr16:84900116(+) A-I      intronic chr16:84913049(+) A-I      intronic chr16:84935999(+) A-I      intronic chr16:84934400(+) A-I      intronic chr16:84938658(+) A-I      intronic chr16:84932640(+) A-I      intronic chr16:84905084(+) A-I      intronic chr16:84932638(+) A-I      intronic chr16:84926386(+) A-I      intronic chr16:84931348(+) A-I      intronic chr16:84864055(+) A-I      intronic chr16:84932732(+) A-I      intronic chr16:84862600(+) A-I      intronic chr16:84934387(+) A-I      intronic chr16:84939339(+) A-I      intronic chr16:84935464(+) A-I      intronic chr16:84936069(+) A-I      intronic chr16:84934403(+) A-I      intronic chr16:84938037(+) A-I      intronic chr16:84937936(+) A-I      intronic chr16:84930873(+) A-I      intronic chr16:84939481(+) A-I      intronic chr16:84930864(+) A-I      intronic chr16:84910137(+) A-I      intronic chr16:84897427(+) A-I      intronic chr16:84931340(+) A-I      intronic chr16:84938011(+) A-I      intronic chr16:84930866(+) A-I      intronic chr16:84939180(+) A-I      intronic chr16:84930835(+) A-I      intronic chr16:84897475(+) A-I      intronic chr16:84895386(+) A-I      intronic chr16:84930795(+) A-I      intronic chr16:84937077(+) A-I      intronic chr16:84932735(+) A-I      intronic chr16:84939124(+) A-I      intronic chr16:84935681(+) A-I      intronic chr16:84909292(+) A-I      intronic chr16:84862606(+) A-I      intronic chr16:84934541(+) A-I      intronic chr16:84897321(+) A-I      intronic chr16:84938040(+) A-I      intronic chr16:84931000(+) A-I      intronic chr16:84929725(+) A-I      intronic chr16:84896027(+) A-I      intronic chr16:84926318(+) A-I      intronic chr16:84935667(+) A-I      intronic chr16:84936562(+) A-I      intronic chr16:84896008(+) A-I      intronic chr16:84939516(+) A-I      intronic chr16:84897483(+) A-I      intronic chr16:84904067(+) A-I      intronic chr16:84934494(+) A-I      intronic chr16:84931410(+) A-I      intronic chr16:84938798(+) A-I      intronic chr16:84880134(+) A-I      intronic chr16:84929751(+) A-I      intronic chr16:84938705(+) A-I      intronic chr16:84926461(+) A-I      intronic chr16:84934498(+) A-I      intronic chr16:84897320(+) A-I      intronic chr16:84904488(+) A-I      intronic chr16:84904486(+) A-I      intronic chr16:84909800(+) A-I      intronic chr16:84935306(+) A-I      intronic chr16:84926054(+) A-I      intronic chr16:84938070(+) A-I      intronic chr16:84934568(+) A-I      intronic chr16:84934431(+) A-I      intronic chr16:84930794(+) A-I      intronic chr16:84928557(+) A-I      intronic chr16:84939092(+) A-I      intronic chr16:84926163(+) A-I      intronic chr16:84928467(+) A-I      intronic chr16:84937975(+) A-I      intronic chr16:84863753(+) A-I      intronic chr16:84910029(+) A-I      intronic chr16:84918697(+) A-I      intronic chr16:84919730(+) A-I      intronic chr16:84909780(+) A-I      intronic chr16:84933070(+) A-I      intronic chr16:84938140(+) A-I      intronic chr16:84909394(+) A-I      intronic chr16:84934402(+) A-I      intronic chr16:84929789(+) A-I      intronic chr16:84928595(+) A-I      intronic chr16:84913108(+) A-I      intronic chr16:84942343(+) A-I      3'UTR

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	CRISPLD2	chr16:84940346-84940347(+) m6A 3'UTR//intron       - chr16:84940449-84940450(+) m6A 3'UTR//intron       -

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	hsa-miR-320a-3p	Apoptotic body Human umbilical vein endothelial cells     19996457 Cytoplasm Cardiomyocytes     31837603 Cytoplasm Nasopharyngeal carcinoma cells     20498841 Cytoplasm Breast adenocarcinoma cells (MCF-7)|Cervical adenocarcinoma cells (HeLa)     24918059 Exosome Human cervical cancer cell line (HeLa)     25760330 Exosome Pooled sera     27278097 Exosome Serum     18589210 Exosome Glioblastoma cells     19011622 Exosome Breast cancer cell line (MCF-7)     20976003 Exosome Ovarian follicular fluid     22116803 Exosome Brain tissue     23382797 Exosome Plasma     23663360 Exosome Human mast cell line (HMC-1)     24009880 Exosome Serum     25135963 Exosome Human esophageal cancer cell line (EC9706)     25184951 Exosome Colon cancer cell line (LIM1863)     25330373 Exosome Cerebrospinal fluid     25420022 Exosome Blood|B lymphoblastoid cells|Breast milk|Chronic lymphocytic leukemia cells|Colon tissue|Endothelial cells|Epithelial cells|Kidney tissue|Lymphoma tissue|Mast cells|Seminal fluid|Tongue tissue     - Extracellular vesicle HEK-293T cells     22849433 Microvesicle Glioblastoma cells     19011622 Microvesicle Plasma     23077538 Microvesicle Seminal plasma     23539611 Microvesicle Follicular fluid     23666971 Microvesicle Serum     24797360 Microvesicle Blood|Breast cell line|Colon cancer cell line (LIM1863)|Fibroblasts|Mesenchymal stem cells|Urine     - Mitochondrion HEK-293 cells|HeLa cells     27396686 Mitochondrion HEK-293 cells|HeLa cells     27563705 Mitochondrion Skeletal muscle myoblasts     21637849 Mitochondrion Cell line (HEK-293|HeLa)     22984580 Nucleolus Breast adenocarcinoma cells (MCF-7)|Cervical adenocarcinoma cells (HeLa)     24918059 Nucleus Breast adenocarcinoma cells (MCF-7)|Cervical adenocarcinoma cells (HeLa)     24918059 Nucleus Cardiomyocytes     31837603 Nucleus Nasopharyngeal carcinoma cells     20498841 Nucleus Neural progenitor cells     21363885
	CRISPLD2	Chromatin K562 cells     - Exosome Blood     -

Interaction Network (The top 100 interactions):

Interactor1: hsa-miR-320a-3p
Interactor2: CRISPLD2

Evidence Support:

Weak-Evidence	Small RNA sequencing
Prediction-Evidence	miRNet
Support Database	ViRBase

References:

PMID	33045840	Target region	None
Source	ViRBase	Interactor1 expression	Upregulation
Tissue or cell line	PBMC cells	Interactor2 expression	Downregulation
Description	FIG. 2.(B) upregulated miRNAs with their predicted downregulated gene targets.