Detail Information

Basic Information:


  VIRBase ID:  

HHID00096240

  Virus:  

Human immunodeficiency virus (HIV)

  Host:  

Homo sapiens

  Confidence Score:  

0.5711

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-96-5p:           ZNF697:      

      *It may take a few minutes to display results.

Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-96-5p ZNF697
miRBase
Accession/Entrez ID		 MIMAT0000095 90874
Organism Homo sapiens Homo sapiens
Category miRNA mRNA
Alias - -

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-96-5p
rs1333938704 chr7:129774745    A/G
rs1483018024 chr7:129774750    G/A
rs772409471 chr7:129774748    G/A
rs776335197 chr7:129774752    T/C
rs957232317 chr7:129774742    A/T
rs587776522 chr7:129774757    C/T
rs587776523 chr7:129774756    G/T

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR ZNF697
chr1:120163012(-) A-I      3'UTR
Resource Symbol Editing Position Change SeqReg exReg PMID
DARNED ZNF697
chr1:120163247(-) A-I exon 3'UTR    21960545

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase ZNF697
chr1:120162858-120162859(-) m6A 3'UTR       24981863//22608085
chr1:120163098-120163099(-) Y 3'UTR       26075521
chr1:120164910-120164911(-) m6A 3'UTR       24981863//27773535
chr1:120164984-120164985(-) m6A 3'UTR       24981863
chr1:120165003-120165004(-) m6A 3'UTR       24981863//27773535
chr1:120165046-120165047(-) m6A 3'UTR       27773535
chr1:120165229-120165230(-) m6A 3'UTR       24209618//25456834//27773535
chr1:120165268-120165269(-) m6A 3'UTR       24209618//25456834
chr1:120165716-120165717(-) m6A CDS       24284625//24981863//27371828//22608085
chr1:120165781-120165782(-) m6A CDS       24284625//24981863//27371828//27773536//22608085
chr1:120166447-120166448(-) m6A CDS       24284625//24209618//25456834//24981863//27371828//27773536//22608085
chr1:120166585-120166586(-) m6A CDS       24284625//24209618//25456834//24981863//27773535//27371828//27773536//22608085
chr1:120166650-120166651(-) m6A CDS       24284625//24209618//25456834//24981863//27773535//27371828//27773536//22608085
chr1:120168535-120168536(-) m6A CDS       24284625//24209618//25456834//24981863//27773535//27371828//27773536//22608085
chr1:120168583-120168584(-) m6A CDS       24284625//24209618//25456834//24981863//27773535//27371828//27773536//22608085
chr1:120168625-120168626(-) m6A CDS       24284625//24209618//25456834//24981863//27773535//27371828//27773536//22608085
chr1:120168637-120168638(-) m6A CDS       24284625//24209618//25456834//24981863//27773535//27371828//27773536//22608085
chr1:120168646-120168647(-) m6A CDS       24284625//24209618//25456834//24981863//27773535//27371828//27773536//22608085
chr1:120168673-120168674(-) m6A CDS       24284625//24209618//25456834//24981863//27773535//27371828//27773536//22608085
chr1:120168682-120168683(-) m6A CDS       24284625//24209618//25456834//24981863//27773535//27371828//27773536//22608085
chr1:120168717-120168718(-) m6A CDS       24284625//24209618//25456834//24981863//27773535//27371828//27773536//22608085
chr1:120190349-120190350(-) m6A 5'UTR       24209618
chr1:120190361-120190362(-) m6A 5'UTR       24209618

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-96-5p
Cytoplasm Breast adenocarcinoma cells (MCF-7)|Cervical adenocarcinoma cells (HeLa)     24918059
Exosome Peripheral blood mononuclear cells     19002258
Exosome Jurkat-derived T cell line (J77cl20)     21505438
Exosome Brain tissue     23382797
Exosome Plasma     23663360
Exosome Seminal fluid|Tongue tissue     -
Microvesicle Colon cancer cell line (LIM1863)|Fibroblasts|Mesenchymal stem cells     -
Mitochondrion Cell line (HEK-293|HeLa)     22984580
Nucleus Breast adenocarcinoma cells (MCF-7)|Cervical adenocarcinoma cells (HeLa)     24918059
ZNF697
Cytosol Human myelogenous leukemia cell line (K-562)     21613539
Exosome Blood     -
Nucleus HCC cell line (HepG2)|K562 cells     -

Related Drug Information:


Resource Symbol Drug Name PubChem
ID		 Function
ncDR hsa-miR-96-5p
(10S,13S,16S,19S)-16-Butan-2-yl-10,11,14-trimethyl-3-(oxiran-2-ylmethyl)-13-propan-2-yl-4-oxa-1,8,11,14,17-pentazabicyclo[17.3.0]docosane-2,5,9,12,15,18-hexone 152771884 Drug resistant
Resource Symbol Drug Name PubChem
ID		 Function Link  
RNAInter hsa-miR-96-5p
Gemcitabine 60750 Drug interaction    RC00001021
Clopidogrel 60606 Drug interaction    RC00001020
Cholesterol 5997 Drug interaction    RC00001016
D-Glucose 5793 Drug interaction    RC00001015
Vorinostat 5311 Drug interaction    RC00001014
Imatinib 5291 Drug interaction    RC00001013
Paclitaxel 36314 Drug interaction    RC00001019
5-Fluorouracil 3385 Drug interaction    RC00001012
Enoxacin 3229 Drug interaction    RC00001011
Doxorubicin 31703 Drug interaction    RC00001018
cis-Diaminedichloroplatinum 2767 Drug interaction    RC00001010
Tamoxifen 2733526 Drug interaction    RC00001023
Verapamil 2520 Drug interaction    RC00001009
N-(3-(5-Chloro-1H-pyrrolo[2,3-b]pyridine-3-carbonyl)-2,4-difluorophenyl)propane-1-sulfonamide 24180719 Drug interaction    RC00001025
Olaparib 23725625 Drug interaction    RC00001024
Arsenic trioxide 14888 Drug interaction    RC00001017
Docetaxel 148124 Drug interaction    RC00001022
Chemotherapy - Drug interaction    RC00008826
TRAIL therapy - Drug interaction    RC00001026
Resource Symbol Drug Name PubChem ID PMID
NoncoRNA hsa-miR-96-5p
Oxaliplatin 9887053       31089750
Paclitaxel 36314       26323677
5-Fluorouracil 3385       31089750
N-(3-(5-Chloro-1H-pyrrolo[2,3-b]pyridine-3-carbonyl)-2,4-difluorophenyl)propane-1-sulfonamide 24180719       26456124
Platinum 23939       25872328

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-96-5p
Interactor2: ZNF697

Evidence Support:


Weak-Evidence Small RNA sequencing
Prediction-Evidence miRNet
Support Database ViRBase

References:


PMID 33045840 Target region None
Source ViRBase Interactor1 expression Upregulation
Tissue or cell line PBMC cells Interactor2 expression Downregulation
Description FIG. 2.(B) upregulated miRNAs with their predicted downregulated gene targets.

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