Basic Information:
VIRBase ID: HHID00093592
Virus: Human orthopneumovirus (HRSV)
Host: Homo sapiens
Confidence Score: 0.9526
Interaction Type: Host-Host interaction
Interactor Information:
Interactor1
Interactor2
Symbol
hsa-miR-29a-3p
GRbeta
miRBase Accession/Entrez ID
MIMAT0000086
GRbeta
Organism
Homo sapiens
Homo sapiens
Category
miRNA
mRNA
Alias
-
ncRNA SNP information:
Resource
Symbol
SNP ID
SNP Position
Ref/Alt
miRNASNP-v3
hsa-miR-29a-3p
RNA Localization:
Resource
Symbol
Subcellular Localization
Tissue or Cell Line
PMID
RNALocate
hsa-miR-29a-3p
Related Drug Information:
Resource
Symbol
Drug Name
PubChem ID
Function
Link
RNAInter
hsa-miR-29a-3p
Resource
Symbol
Drug Name
PubChem ID
PMID
NoncoRNA
hsa-miR-29a-3p
Interaction Network (The top 100 interactions) :
Interactor1: hsa-miR-29a-3p
Interactor2: GRbeta
Evidence Support:
Strong-Evidence
Dual luciferase reporter assay//qRT-PCR//Western blot
Support Database
ViRBase
References:
PMID
31128120
Target region
3'UTR
Source
ViRBase
Interactor1 expression
Upregulation
Tissue or cell line
A549 cells
Interactor2 expression
Downregulation
Description
We first found that expression of GR mRNA (Fig 2, A) and protein (Fig 2, B) was significantly increased in the miR-29a inhibitor group compared with that in the control miRNA group. In line with those data, FKBP51 and GILZ expression increased in the miR-29a inhibitor group compared with the miRNA control group (Fig 2, C).