Detail Information

Basic Information:


  VIRBase ID:  

HHID00093451

  Virus:  

Oropouche virus

  Host:  

Homo sapiens

  Confidence Score:  

0.6061

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-217-3p:           MMGT1:      

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Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-217-3p MMGT1
miRBase
Accession/Entrez ID		 MIMAT0037308 93380
Organism Homo sapiens Homo sapiens
Category miRNA mRNA
Alias - EMC5//TMEM32

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-217-3p
rs1187223790 chr2:55982995    A/G
rs1252320359 chr2:55982988    A/G
rs1252320359 chr2:55982988    A/T
rs1276986732 chr2:55982986    C/T
rs41291173 chr2:55983005    G/A
rs41291173 chr2:55983005    G/C
rs1291461563 chr2:55983001    T/C
rs374669006 chr2:55983004    T/C

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR MMGT1
chrX:135052992(-) A-I      intronic
chrX:135048677(-) A-I      intronic
chrX:135053064(-) A-I      intronic
chrX:135053054(-) A-I      intronic
chrX:135053016(-) A-I      intronic
chrX:135052436(-) A-I      intronic
chrX:135051665(-) A-I      intronic
chrX:135050818(-) A-I      intronic
chrX:135052388(-) A-I      intronic
chrX:135051677(-) A-I      intronic
chrX:135052352(-) A-I      intronic

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase MMGT1
chrX:135044511-135044512(-) m6A 3'UTR       -
chrX:135045337-135045338(-) m6A 3'UTR       24981863//27773535
chrX:135045360-135045361(-) m6A 3'UTR       24981863//27773535
chrX:135045539-135045540(-) Tm 3'UTR       -
chrX:135047073-135047074(-) m6A 3'UTR       24284625//24981863//26404942
chrX:135047116-135047117(-) m6A 3'UTR       24284625//24981863//26404942
chrX:135047151-135047152(-) m6A 3'UTR       24284625//24981863//26404942
chrX:135047156-135047157(-) m6A 3'UTR       24284625//24981863//26404942
chrX:135047203-135047204(-) m6A CDS       24284625//24981863
chrX:135047246-135047247(-) m6A CDS       24284625
chrX:135049559-135049560(-) m6A CDS       24284625
chrX:135049578-135049579(-) m6A CDS       24284625

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-217-3p
Cytoplasm Cell lines (Aspc-1Panc-1)     28701723
Exosome Brain tissue     23382797
Exosome Plasma     23663360
Nucleus Cell lines (Aspc-1Panc-1)     28701723
MMGT1
Exosome Blood     -
Nucleolus K562 cells     -

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-217-3p
Interactor2: MMGT1

Evidence Support:


Weak-Evidence miRNA array
Prediction-Evidence miRanda//miRBase//miRTarget2//PicTar//TarBase//Targetscan
Support Database ViRBase

References:


PMID 29813068 Target region None
Source ViRBase Interactor1 expression None
Tissue or cell line Huh-7 cells Interactor2 expression None
Description Target genes predicted by at least 3 out of 6 of those databases were considered candidates. We predicted 195 cellular genes to interact with miR-217, miR-576-3p, or both, using that criterion (S2 Table).

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