Basic Information:

  VIRBase ID:  

HHID00092864

  Virus:  

Influenza A virus (A/Brisbane/10/2007(H3N2))

  Host:  

Homo sapiens

  Confidence Score:  

0.6743

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-937-5p:  MIMAT0022938          FAS:  NR_028035     

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Interactor Information:

	Interactor1	Interactor2
Symbol	hsa-miR-937-5p	FAS
miRBase Accession/Entrez ID	MIMAT0022938	355
Organism	Homo sapiens	Homo sapiens
Category	miRNA	mRNA
Alias	-	ALPS1A//APO-1//APT1//CD95//FAS1//FASTM//TNFRSF6

ncRNA SNP information:

Resource	Symbol	SNP ID	SNP Position	Ref/Alt
miRNASNP-v3	hsa-miR-937-5p	rs1206103807 chr8:143813013    G/A rs1213977544 chr8:143813019    C/T rs1318905167 chr8:143813020    C/G rs1462097886 chr8:143813013    GCCCCA/G rs372364994 chr8:143813012    A/G rs761985672 chr8:143813016    C/A rs761985672 chr8:143813016    C/G rs766167551 chr8:143813018    A/G rs769052591 chr8:143813010    C/A rs769052591 chr8:143813010    C/T rs1194683616 chr8:143813023    G/A rs759210043 chr8:143813027    C/T rs776649723 chr8:143813022    T/G

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	FAS	chr10:90750513-90750514(+) m6A 5'UTR       24981863 chr10:90750576-90750577(+) m6A 5'UTR       24981863 chr10:90750648-90750649(+) m6A CDS       24981863 chr10:90750813-90750814(+) m6A exon//intron       - chr10:90750836-90750837(+) m6A exon//intron       - chr10:90750873-90750874(+) m6A exon//intron       24209618 chr10:90750948-90750949(+) m6A exon//intron       24284625//24209618//24981863 chr10:90750986-90750987(+) m6A exon//intron       24284625//24981863 chr10:90751035-90751036(+) m6A exon//intron       24981863 chr10:90751059-90751060(+) m6A exon//intron       24981863 chr10:90751067-90751068(+) m6A exon//intron       24981863 chr10:90774004-90774005(+) m6A 3'UTR//CDS       24284625//24981863//22608085 chr10:90774014-90774015(+) m6A 3'UTR//CDS       24284625//24981863//22608085 chr10:90774132-90774133(+) m6A 3'UTR//CDS       24284625//24209618//24981863//26404942//22575960//22608085 chr10:90774148-90774149(+) m6A 3'UTR//CDS       24284625//24209618//24981863//26404942//22575960//22608085 chr10:90774175-90774176(+) m6A 3'UTR//CDS       24209618//24981863//26404942//22608085 chr10:90774215-90774216(+) m6A 3'UTR       24209618//24981863//26404942//22608085

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	hsa-miR-937-5p	Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     - Microvesicle Cell lines(GBM46|GBM8|HaCaT|K562|MCF-10A|MCF-7|MGG75)|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocytes     -
	FAS	Exosome Blood     -

Interaction Network (The top 100 interactions):

Interactor1: hsa-miR-937-5p
Interactor2: FAS

Evidence Support:

Weak-Evidence	MiRNA microarray//RNA-Seq
Prediction-Evidence	microRNA.org//PITA//Targetscan
Support Database	ViRBase

References:

PMID	30605755	Target region	None
Source	ViRBase	Interactor1 expression	Downregulation
Tissue or cell line	A549 cells	Interactor2 expression	Upregulation
Description	A. Relationships between miRNAs and inversely correlated mRNAs involved in the influenza A pathway.