Detail Information

Basic Information:


  VIRBase ID:  

HHID00092856

  Virus:  

Influenza A virus (A/Brisbane/10/2007(H3N2))

  Host:  

Homo sapiens

  Confidence Score:  

0.6743

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-4763-3p:           STAT2:      

      *It may take a few minutes to display results.

Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-4763-3p STAT2
miRBase
Accession/Entrez ID		 MIMAT0019913 6773
Organism Homo sapiens Homo sapiens
Category miRNA mRNA
Alias - IMD44//ISGF-3//P113//PTORCH3//STAT113

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-4763-3p
rs111509618 chr22:46113644    C/CG
rs1293184635 chr22:46113643    G/A
rs1293184635 chr22:46113643    G/T
rs1480117916 chr22:46113632    G/T
rs574975013 chr22:46113636    G/A
rs748191060 chr22:46113644    C/G
rs748191060 chr22:46113644    C/T
rs768794912 chr22:46113637    T/G
rs781389774 chr22:46113639    C/T
rs909576682 chr22:46113642    G/A
rs927719598 chr22:46113645    G/A
rs927719598 chr22:46113645    G/C
rs927719598 chr22:46113645    G/T
rs1193544941 chr22:46113631    G/A
rs1216027531 chr22:46113627    C/T
rs1339640536 chr22:46113626    G/C
rs1483337396 chr22:46113624    AGGCAGG/A
rs967155183 chr22:46113630    G/T

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR STAT2
chr12:56736312(-) A-I      3'UTR
chr12:56736305(-) A-I      3'UTR
chr12:56736292(-) A-I      3'UTR
chr12:56736288(-) A-I      3'UTR
chr12:56746299(-) A-I      intronic
chr12:56746873(-) A-I      intronic
chr12:56746896(-) A-I      intronic
chr12:56747671(-) A-I      intronic
chr12:56736343(-) A-I      3'UTR
chr12:56736328(-) A-I      3'UTR
chr12:56736370(-) A-I      3'UTR
chr12:56736368(-) A-I      3'UTR
chr12:56736372(-) A-I      3'UTR
chr12:56736322(-) A-I      3'UTR
chr12:56736371(-) A-I      3'UTR
chr12:56745879(-) A-I      intronic
chr12:56745896(-) A-I      intronic
chr12:56746283(-) A-I      intronic
chr12:56745737(-) A-I      intronic
chr12:56746797(-) A-I      intronic
chr12:56747552(-) A-I      intronic
chr12:56746870(-) A-I      intronic
chr12:56746875(-) A-I      intronic
chr12:56747055(-) A-I      intronic
chr12:56745739(-) A-I      intronic
chr12:56746889(-) A-I      intronic
chr12:56746914(-) A-I      intronic
chr12:56745744(-) A-I      intronic
chr12:56746936(-) A-I      intronic
chr12:56745792(-) A-I      intronic
chr12:56745793(-) A-I      intronic
chr12:56747535(-) A-I      intronic
chr12:56746941(-) A-I      intronic
chr12:56752167(-) A-I      intronic
chr12:56745841(-) A-I      intronic
chr12:56746956(-) A-I      intronic
chr12:56752162(-) A-I      intronic
chr12:56752141(-) A-I      intronic
chr12:56745805(-) A-I      intronic
chr12:56746963(-) A-I      intronic
chr12:56752138(-) A-I      intronic
chr12:56747566(-) A-I      intronic
chr12:56746743(-) A-I      intronic
chr12:56746995(-) A-I      intronic
chr12:56741391(-) A-I      intronic
chr12:56747680(-) A-I      intronic
chr12:56745774(-) A-I      intronic
chr12:56747173(-) A-I      intronic
chr12:56746883(-) A-I      intronic
chr12:56747694(-) A-I      intronic
chr12:56747167(-) A-I      intronic
chr12:56741567(-) A-I      intronic
chr12:56745886(-) A-I      intronic
chr12:56747747(-) A-I      intronic
chr12:56746986(-) A-I      intronic
chr12:56741424(-) A-I      intronic
chr12:56741450(-) A-I      intronic
chr12:56747045(-) A-I      intronic
chr12:56746290(-) A-I      intronic
chr12:56747574(-) A-I      intronic
chr12:56753115(-) A-I      intronic
chr12:56747615(-) A-I      intronic
chr12:56746865(-) A-I      intronic
chr12:56736258(-) A-I      3'UTR
chr12:56735958(-) A-I      3'UTR
chr12:56746884(-) A-I      intronic
chr12:56747697(-) A-I      intronic
chr12:56741414(-) A-I      intronic
chr12:56747704(-) A-I      intronic
chr12:56745915(-) A-I      intronic
chr12:56747658(-) A-I      intronic
chr12:56747533(-) A-I      intronic
chr12:56747632(-) A-I      intronic
chr12:56752633(-) A-I      intronic
chr12:56752135(-) A-I      intronic
chr12:56745681(-) A-I      intronic
chr12:56746297(-) A-I      intronic
chr12:56745815(-) A-I      intronic
chr12:56747032(-) A-I      intronic
chr12:56746728(-) A-I      intronic
chr12:56746701(-) A-I      intronic
chr12:56747018(-) A-I      intronic
chr12:56747556(-) A-I      intronic
chr12:56746696(-) A-I      intronic
chr12:56747586(-) A-I      intronic
chr12:56746830(-) A-I      intronic
chr12:56747650(-) A-I      intronic
chr12:56745933(-) A-I      intronic
chr12:56747573(-) A-I      intronic
chr12:56746365(-) A-I      intronic
chr12:56746962(-) A-I      intronic
chr12:56746987(-) A-I      intronic
chr12:56738667(-) A-I      intronic
chr12:56753116(-) A-I      intronic
chr12:56746906(-) A-I      intronic
chr12:56747561(-) A-I      intronic
chr12:56745876(-) A-I      intronic
chr12:56753145(-) A-I      intronic
chr12:56745962(-) A-I      intronic
chr12:56747717(-) A-I      intronic
chr12:56746324(-) A-I      intronic
chr12:56746892(-) A-I      intronic
chr12:56747575(-) A-I      intronic
chr12:56752674(-) A-I      intronic
chr12:56747612(-) A-I      intronic
chr12:56747648(-) A-I      intronic
chr12:56741410(-) A-I      intronic
chr12:56745814(-) A-I      intronic
chr12:56746803(-) A-I      intronic
chr12:56750878(-) A-I      intronic
chr12:56745769(-) A-I      intronic
chr12:56753171(-) A-I      intronic
chr12:56747154(-) A-I      intronic
chr12:56753158(-) A-I      intronic
chr12:56752676(-) A-I      intronic
chr12:56745745(-) A-I      intronic
chr12:56746961(-) A-I      intronic
chr12:56747736(-) A-I      intronic
chr12:56747693(-) A-I      intronic
chr12:56746298(-) A-I      intronic
chr12:56735931(-) A-I      3'UTR
chr12:56735997(-) A-I      3'UTR
chr12:56736335(-) A-I      3'UTR
Resource Symbol Editing Position Change SeqReg exReg PMID
DARNED STAT2
chr12:56745815(-) A-I intron -    22327324
chr12:56746830(-) A-I intron -    22327324
chr12:56746892(-) A-I intron -    22327324
chr12:56746906(-) A-I intron -    22327324
chr12:56747612(-) A-I intron -    22327324
chr12:56747704(-) A-I intron -    22327324
chr12:56746324(-) A-I intron -    21960545
chr12:56747045(-) A-I intron -    21960545
chr12:56747154(-) A-I intron -    21960545
chr12:56747167(-) A-I intron -    21960545
chr12:56736080(-) G-T exon 3'UTR    22484847
chr12:56736335(-) A-G exon 3'UTR    22484847
chr12:56741891(-) C-A intron -    22484847
chr12:56741892(-) T-A intron -    22484847
chr12:56745769(-) A-G intron -    22484847
chr12:56745774(-) A-G intron -    22484847
chr12:56745815(-) A-G intron -    22484847
chr12:56746365(-) A-G intron -    22484847
chr12:56746803(-) A-G intron -    22484847
chr12:56746830(-) A-G intron -    22484847
chr12:56746892(-) A-G intron -    22484847
chr12:56746906(-) A-G intron -    22484847
chr12:56746961(-) A-G intron -    22484847
chr12:56746962(-) A-G intron -    22484847
chr12:56746987(-) A-G intron -    22484847
chr12:56747561(-) A-G intron -    22484847
chr12:56747575(-) A-G intron -    22484847
chr12:56747612(-) A-G intron -    22484847
chr12:56747658(-) A-G intron -    22484847
chr12:56747680(-) A-G intron -    22484847
chr12:56747694(-) A-G intron -    22484847
chr12:56747704(-) A-G intron -    22484847
chr12:56753115(-) A-G intron -    22484847
chr12:56741238(-) T-C intron -    22484847
chr12:56743802(-) G-A intron -    22484847
chr12:56745745(-) A-G intron -    22484847
chr12:56745814(-) A-G intron -    22484847
chr12:56745962(-) A-G intron -    22484847
chr12:56746883(-) A-G intron -    22484847
chr12:56746884(-) A-G intron -    22484847
chr12:56746995(-) A-G intron -    22484847
chr12:56747573(-) A-G intron -    22484847
chr12:56747574(-) A-G intron -    22484847
chr12:56747586(-) A-G intron -    22484847
chr12:56747693(-) A-G intron -    22484847

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase STAT2
chr12:56737169-56737170(-) m6A 3'UTR//exon       24284625
chr12:56737196-56737197(-) m6A CDS//exon       24284625//27773535
chr12:56737248-56737249(-) m6A CDS//exon       24284625//24981863//27773535//27371828//22608085
chr12:56737305-56737306(-) m6A CDS//exon       24284625//24981863//28052920//27773535//27371828//22608085
chr12:56737625-56737626(-) m6A CDS//exon       24284625//24981863//28052920//27773535//27371828//22608085
chr12:56737633-56737634(-) m6A CDS//exon       24284625//24981863//28052920//27773535//27371828//22608085
chr12:56737681-56737682(-) m6A CDS//exon       24284625//24981863//28052920//27773535//27371828//22608085
chr12:56737688-56737689(-) m6A CDS//exon       24284625//24981863//28052920//27773535//27371828//22608085
chr12:56737704-56737705(-) m6A CDS//exon       24284625//24981863//28052920//27773535//27371828//22608085
chr12:56737814-56737815(-) m6A CDS//exon       24284625//24981863//28052920//27773535//27371828//27773536
chr12:56737849-56737850(-) m6A CDS//exon       24284625//24981863//28052920//27371828//27773536
chr12:56737906-56737907(-) m6A CDS//exon       24284625//24981863//27773535//27371828
chr12:56739955-56739956(-) m6A CDS//exon       24284625//27773535//27371828
chr12:56743269-56743270(-) m6A CDS//exon       27773535
chr12:56743419-56743420(-) m6A CDS//exon       24284625//27773535
chr12:56743469-56743470(-) m6A exon//intron       27773535
chr12:56743484-56743485(-) m6A exon//intron       27773535
chr12:56744085-56744086(-) m6A exon//intron       24981863
chr12:56744113-56744114(-) m6A exon//intron       24981863
chr12:56744141-56744142(-) m6A exon//intron       24981863
chr12:56744659-56744660(-) m6A CDS//exon       27371828
chr12:56744885-56744886(-) m6A CDS//exon       27371828
chr12:56744909-56744910(-) m6A CDS//exon       27371828
chr12:56744936-56744937(-) m6A CDS//exon       27371828
chr12:56744957-56744958(-) m6A CDS//exon       27371828
chr12:56745036-56745037(-) m6A exon//intron       27773535//27371828
chr12:56745055-56745056(-) m6A exon//intron       27371828
chr12:56745123-56745124(-) m6A CDS//exon//intron       27371828
chr12:56745173-56745174(-) m6A CDS//exon//intron       27371828
chr12:56748253-56748254(-) m6A CDS//exon       27371828
chr12:56748263-56748264(-) m6A CDS//exon       27371828
chr12:56748574-56748575(-) m6A CDS//exon       27371828
chr12:56748579-56748580(-) m6A CDS//exon       27371828
chr12:56748590-56748591(-) m6A CDS//exon       27371828
chr12:56748617-56748618(-) m6A CDS//exon       27371828
chr12:56748628-56748629(-) m6A CDS//exon       27371828
chr12:56748641-56748642(-) m6A CDS//exon       27371828
chr12:56748671-56748672(-) m6A exon//intron       27371828
chr12:56748679-56748680(-) m6A exon//intron       27371828
chr12:56748705-56748706(-) m6A exon//intron       27371828
chr12:56748845-56748846(-) m6A exon//intron       -
chr12:56748874-56748875(-) m6A exon//intron       -
chr12:56748956-56748957(-) m6A exon//intron       -
chr12:56750227-56750228(-) m6A CDS//exon//intron       27371828
chr12:56750233-56750234(-) m6A CDS//exon//intron       27371828
chr12:56750266-56750267(-) m6A CDS//exon//intron       24981863//27371828
chr12:56753857-56753858(-) m6A 5'UTR//exon       24284625//24981863//27371828

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-4763-3p
Exosome Pooled sera     27278097
Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     -
Microvesicle Cell lines(GBM46|GBM8|HaCaT|K562|MCF-10A|MCF-7|MGG75)|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocytes     -
STAT2
Chromatin K562 cells     -
Exosome Blood     -
Membrane HCC cell line (HepG2)     -
Nucleolus K562 cells     -
Nucleoplasm K562 cells     -
Nucleus Nasopharyngeal carcinoma cells     20498841

Related Drug Information:


Resource Symbol Drug Name PubChem
ID		 Function Link  
RNAInter hsa-miR-4763-3p
Vincristine 5978 Drug interaction    RC00008583
5-Fluorouracil 3385 Drug interaction    RC00008582
Doxorubicin 31703 Drug interaction    RC00008584
cis-Diaminedichloroplatinum 2767 Drug interaction    RC00008581
Resource Symbol Drug Name PubChem ID PMID
NoncoRNA hsa-miR-4763-3p
5-Fluorouracil 3385       23525256

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-4763-3p
Interactor2: STAT2

Evidence Support:


Weak-Evidence MiRNA microarray//RNA-Seq
Prediction-Evidence microRNA.org//PITA//Targetscan
Support Database ViRBase

References:


PMID 30605755 Target region None
Source ViRBase Interactor1 expression Downregulation
Tissue or cell line A549 cells Interactor2 expression Upregulation
Description B. Relationships between miRNAs and inversely correlated mRNAs involved in the host defense to virus. Green and red represent downregulated and upregulated genes, while triangles and circles represent miRNAs and target gene mRNAs, respectively.

Starting a new search, please wait ...