Detail Information

Basic Information:


  VIRBase ID:  

HHID00092829

  Virus:  

Influenza A virus (A/Brisbane/10/2007(H3N2))

  Host:  

Homo sapiens

  Confidence Score:  

0.6743

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-4530:           ADAR:      

      *It may take a few minutes to display results.

Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-4530 ADAR
miRBase
Accession/Entrez ID		 MIMAT0019069 103
Organism Homo sapiens Homo sapiens
Category miRNA mRNA
Alias - ADAR1//AGS6//DRADA//DSH//DSRAD//G1P1//IFI-4//IFI4//K88DSRBP//P136

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-4530
rs1158939434 chr19:39409633    C/G
rs1302370391 chr19:39409637    T/C
rs1405299984 chr19:39409645    G/A

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR ADAR
chr1:154565377(-) A-I      intronic
chr1:154585889(-) A-I      intronic
chr1:154586214(-) A-I      intronic
chr1:154585893(-) A-I      intronic
chr1:154586304(-) A-I      intronic
chr1:154598264(-) A-I      intronic
chr1:154598663(-) A-I      intronic
chr1:154585032(-) A-I      intronic
chr1:154584936(-) A-I      intronic
chr1:154598659(-) A-I      intronic
chr1:154585420(-) A-I      intronic
chr1:154585426(-) A-I      intronic
chr1:154598785(-) A-I      intronic
chr1:154584975(-) A-I      intronic
chr1:154586215(-) A-I      intronic
chr1:154586298(-) A-I      intronic
chr1:154585436(-) A-I      intronic
chr1:154584974(-) A-I      intronic
chr1:154584973(-) A-I      intronic
chr1:154585004(-) A-I      intronic
chr1:154585850(-) A-I      intronic
chr1:154598786(-) A-I      intronic
chr1:154565449(-) A-I      intronic
chr1:154586280(-) A-I      intronic
chr1:154598398(-) A-I      intronic
chr1:154565463(-) A-I      intronic
chr1:154565446(-) A-I      intronic
chr1:154586297(-) A-I      intronic
chr1:154584942(-) A-I      intronic
chr1:154578706(-) A-I      5'UTR
chr1:154598541(-) A-I      intronic
chr1:154598538(-) A-I      intronic
chr1:154586049(-) A-I      intronic
chr1:154585921(-) A-I      intronic
chr1:154588006(-) A-I      intronic
chr1:154586193(-) A-I      intronic
chr1:154584978(-) A-I      intronic
chr1:154566590(-) A-I      intronic
chr1:154598428(-) A-I      intronic
chr1:154586050(-) A-I      intronic
chr1:154598105(-) A-I      intronic
chr1:154585943(-) A-I      intronic
chr1:154598880(-) A-I      intronic
chr1:154598466(-) A-I      intronic
chr1:154598078(-) A-I      intronic
chr1:154598309(-) A-I      intronic
chr1:154563373(-) A-I      intronic
chr1:154586007(-) A-I      intronic
chr1:154563368(-) A-I      intronic
chr1:154598317(-) A-I      intronic
chr1:154585857(-) A-I      intronic
chr1:154585043(-) A-I      intronic
Resource Symbol Editing Position Change SeqReg exReg PMID
DARNED ADAR
chr1:154563368(-) A-G intron -    22484847
chr1:154578706(-) A-G intron -    22484847
chr1:154584942(-) A-G intron -    22484847
chr1:154585857(-) A-G intron -    22484847
chr1:154586007(-) A-G intron -    22484847
chr1:154586193(-) A-G intron -    22484847
chr1:154586280(-) A-G intron -    22484847
chr1:154586297(-) A-G intron -    22484847
chr1:154588006(-) A-G intron -    22484847
chr1:154598078(-) A-G intron -    22484847
chr1:154598309(-) A-G intron -    22484847
chr1:154598428(-) A-G intron -    22484847
chr1:154598466(-) A-G intron -    22484847
chr1:154598538(-) A-G intron -    22484847
chr1:154598541(-) A-G intron -    22484847
chr1:154598880(-) A-G intron -    22484847

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase ADAR
chr1:154554554-154554555(-) m6A 3'UTR       28052920//22608085
chr1:154554661-154554662(-) m6A 3'UTR       24284625//25456834//24981863//28052920//22575960//22608085
chr1:154554675-154554676(-) m6A 3'UTR       24284625//25456834//24981863//28052920//22575960//22608085
chr1:154554729-154554730(-) m6A 3'UTR       24284625//25456834//22575960
chr1:154554813-154554814(-) m6A 3'UTR       24284625
chr1:154554935-154554936(-) m6A 3'UTR       27773535
chr1:154555094-154555095(-) m6A 3'UTR       27773535
chr1:154555117-154555118(-) m6A 3'UTR       27773535
chr1:154555775-154555776(-) Cm 3'UTR       -
chr1:154556050-154556051(-) m6A 3'UTR       26404942
chr1:154557049-154557050(-) m6A 3'UTR       24284625//26404942
chr1:154557140-154557141(-) m6A 3'UTR//exon       24284625//24209618//24981863//26404942//27773535
chr1:154557303-154557304(-) m6A CDS//exon       24284625//24209618//25456834//24981863//28052920//26404942//27773535//27371828//22575960//22608085
chr1:154557320-154557321(-) m6A CDS//exon       24284625//24209618//25456834//24981863//28052920//26404942//27773535//27371828//22575960//22608085
chr1:154557333-154557334(-) m6A CDS//exon       24284625//24209618//25456834//24981863//28052920//26404942//27773535//27371828//22575960//22608085
chr1:154557372-154557373(-) m6A CDS//exon       24284625//24209618//25456834//24981863//28052920//26404942//27773535//27371828//22575960//22608085
chr1:154557425-154557426(-) m6A CDS//exon       24284625//24209618//25456834//24981863//28052920//26404942//27773535//27371828//22575960//22608085
chr1:154557483-154557484(-) m6A CDS//exon       24284625//24209618//24981863//22575960//22608085
chr1:154562661-154562662(-) m6A CDS//intron       27773535//27773536
chr1:154562703-154562704(-) m6A CDS//intron       27773535//27773536
chr1:154569297-154569298(-) m6A CDS       27773535//22575960
chr1:154569379-154569380(-) m6A CDS       27773535//22575960
chr1:154569711-154569712(-) m6A CDS       26404942//22575960
chr1:154570308-154570309(-) m6A CDS       24284625//27773535
chr1:154570354-154570355(-) m6A CDS       24284625//27773535
chr1:154570436-154570437(-) m6A CDS       24284625//24981863//28052920//26404942//27773535//27371828//27773536
chr1:154570932-154570933(-) m6A CDS       24284625//24981863//28052920//26404942//27773535//27371828//27773536
chr1:154572662-154572663(-) m6A exon//intron       24284625//24981863
chr1:154572732-154572733(-) m6A exon//intron       24284625//24981863
chr1:154572976-154572977(-) m6A exon//intron       27371828
chr1:154573020-154573021(-) m6A exon//intron       27371828
chr1:154573045-154573046(-) m6A exon//intron       27371828
chr1:154573062-154573063(-) m6A exon//intron       27371828
chr1:154573305-154573306(-) m6A exon//intron       27773535
chr1:154573326-154573327(-) m6A exon//intron       24284625//27773535
chr1:154573333-154573334(-) m6A exon//intron       24284625//27773535
chr1:154573497-154573498(-) m6A exon//intron       24284625//24981863//27773535//22575960//22608085
chr1:154573508-154573509(-) m6A exon//intron       24284625//24981863//27773535//22575960//22608085
chr1:154573521-154573522(-) m6A CDS//exon       24284625//24981863//26404942//27773535//27371828//22575960//22608085
chr1:154573533-154573534(-) m6A CDS//exon       24284625//24981863//26404942//27773535//27371828//22575960//22608085
chr1:154573565-154573566(-) m6A CDS//exon       24284625//24209618//24981863//26404942//27773535//27371828//22575960//22608085
chr1:154573609-154573610(-) m6A CDS//exon       24284625//24209618//24981863//28052920//26404942//27773535//27371828//22575960//22608085
chr1:154573632-154573633(-) m6A CDS//exon       24284625//24209618//24981863//28052920//26404942//27773535//27371828//22575960//22608085
chr1:154573818-154573819(-) m6A CDS//exon       24284625//24209618//25456834//24981863//28052920//26404942//27773535//27371828//22575960//22608085
chr1:154573824-154573825(-) m6A CDS//exon       24284625//24209618//25456834//24981863//28052920//26404942//27773535//27371828//22575960//22608085
chr1:154573833-154573834(-) m6A CDS//exon       24284625//24209618//25456834//24981863//28052920//26404942//27773535//27371828//22575960//22608085
chr1:154573839-154573840(-) m6A CDS//exon       24284625//24209618//25456834//24981863//28052920//26404942//27773535//27371828//22575960//22608085
chr1:154573855-154573856(-) m6A CDS//exon       24284625//24209618//25456834//24981863//28052920//27773535//27371828//22575960//22608085
chr1:154573875-154573876(-) m6A CDS//exon       24284625//24209618//25456834//24981863//28052920//27773535//27371828//22575960//22608085
chr1:154573970-154573971(-) m6A CDS//exon       24284625//24209618//25456834//24981863//28052920//27773535//27371828//22575960//22608085
chr1:154573994-154573995(-) m6A CDS//exon       24284625//24209618//25456834//24981863//28052920//27773535//27371828//22575960//22608085
chr1:154574008-154574009(-) m6A CDS//exon       24284625//24209618//25456834//24981863//28052920//26404942//27773535//27371828//22575960//22608085
chr1:154574047-154574048(-) m6A CDS//exon       24284625//24209618//25456834//24981863//28052920//26404942//27773535//27371828//22575960//22608085
chr1:154574075-154574076(-) m6A CDS//exon       24284625//24209618//25456834//24981863//28052920//26404942//27773535//27371828//22575960//22608085
chr1:154574082-154574083(-) m6A CDS//exon       24284625//24209618//25456834//24981863//28052920//26404942//27773535//27371828//22575960//22608085
chr1:154574233-154574234(-) m6A 5'UTR//CDS//exon       24284625//24209618//24981863//26404942//27773535//27371828//22575960//22608085
chr1:154574278-154574279(-) m6A 5'UTR//CDS//exon       24284625//24209618//24981863//26404942//27773535//27371828//22575960//22608085
chr1:154574286-154574287(-) m6A 5'UTR//CDS//exon       24284625//24209618//24981863//26404942//27773535//27371828//22575960//22608085
chr1:154574299-154574300(-) m6A 5'UTR//CDS//exon       24284625//24209618//24981863//27773535//27371828//27773536//22575960//22608085
chr1:154574305-154574306(-) m6A 5'UTR//CDS//exon       24284625//24209618//24981863//27773535//27371828//27773536//22575960//22608085
chr1:154574329-154574330(-) m6A 5'UTR//CDS//exon       24284625//24981863//27773535//27371828//27773536//22575960//22608085
chr1:154574334-154574335(-) m6A 5'UTR//CDS//exon       24284625//24981863//27773535//27371828//27773536//22575960//22608085
chr1:154574356-154574357(-) m6A 5'UTR//CDS//exon       24284625//24981863//27773535//27371828//27773536//22575960//22608085
chr1:154574419-154574420(-) m6A 5'UTR//CDS//exon       24284625//24981863//27371828//27773536//22575960//22608085
chr1:154574425-154574426(-) m6A 5'UTR//CDS//exon       24284625//24981863//27371828//27773536//22575960//22608085
chr1:154574433-154574434(-) m6A 5'UTR//CDS//exon       24284625//24981863//27371828//27773536//22575960//22608085
chr1:154574446-154574447(-) m6A 5'UTR//CDS//exon       24284625//24981863//27371828//27773536//22575960//22608085
chr1:154574452-154574453(-) m6A 5'UTR//CDS//exon       24284625//24981863//27371828//27773536//22575960//22608085
chr1:154574481-154574482(-) m6A 5'UTR//CDS//exon       24284625//25456834//24981863//27371828//27773536//22575960//22608085
chr1:154574503-154574504(-) m6A 5'UTR//CDS//exon       24284625//25456834//24981863//27371828//27773536//22575960//22608085
chr1:154574546-154574547(-) m6A 5'UTR//CDS//exon       24284625//25456834//24981863//28052920//26404942//27773535//27371828//27773536//22575960//22608085
chr1:154574618-154574619(-) m6A 5'UTR//CDS//exon       24284625//25456834//24981863//28052920//26404942//27773535//27371828//27773536//22575960//22608085
chr1:154574625-154574626(-) m6A 5'UTR//CDS//exon       24284625//25456834//24981863//28052920//26404942//27773535//27371828//27773536//22575960//22608085
chr1:154574697-154574698(-) m6A 5'UTR//CDS//exon       24284625//24209618//25456834//24981863//28052920//26404942//27773535//27371828//27773536//22575960//22608085
chr1:154574721-154574722(-) m6A 5'UTR//CDS//exon       24284625//24209618//25456834//24981863//28052920//26404942//27773535//27371828//27773536//22575960//22608085
chr1:154574851-154574852(-) m6A 5'UTR//CDS//exon//intron       24284625//24209618//25456834//24981863//28052920//26404942//27371828//27773536//22575960//22608085
chr1:154574907-154574908(-) m6A 5'UTR//CDS//exon       24284625//24209618//25456834//24981863//28052920//26404942//27371828//22575960//22608085
chr1:154574936-154574937(-) m6A 5'UTR//CDS//exon       24284625//24209618//25456834//24981863//28052920//26404942//27371828//22575960//22608085
chr1:154575048-154575049(-) m6A 5'UTR//CDS//exon       24284625//24209618//24981863//27773535//27371828//22575960//22608085
chr1:154580630-154580631(-) m6A 5'UTR//intron       24209618//24981863//27371828//27773536//22575960
chr1:154580659-154580660(-) m6A 5'UTR//intron       24209618//24981863//27371828//27773536
chr1:154581254-154581255(-) m6A exon//intron       24209618//24981863
chr1:154600334-154600335(-) m6A 5'UTR//exon//intron       24209618//24981863
chr1:154600449-154600450(-) m6A exon       24981863

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-4530
Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     -
Microvesicle Cell lines(GBM46|GBM8|HaCaT|K562|MCF-10A|MCF-7|MGG75)|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocytes     -
ADAR
Chromatin K562 cells     -
Cytosol Human myelogenous leukemia cell line (K-562)     21613539
Exosome Blood     -
Nucleolus K562 cells     -
Nucleoplasm K562 cells     -
Nucleus HeLa-S3 cells|K562 cells     -
Ribosome HEK-293 cells     22199352
Ribosome Colon cancer cells     24393600

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-4530
Interactor2: ADAR

Evidence Support:


Weak-Evidence MiRNA microarray//RNA-Seq
Prediction-Evidence microRNA.org//PITA//Targetscan
Support Database ViRBase

References:


PMID 30605755 Target region None
Source ViRBase Interactor1 expression Downregulation
Tissue or cell line A549 cells Interactor2 expression Upregulation
Description B. Relationships between miRNAs and inversely correlated mRNAs involved in the host defense to virus. Green and red represent downregulated and upregulated genes, while triangles and circles represent miRNAs and target gene mRNAs, respectively.

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