Detail Information

Basic Information:


  VIRBase ID:  

HHID00092724

  Virus:  

Influenza A virus (A/Brisbane/10/2007(H3N2))

  Host:  

Homo sapiens

  Confidence Score:  

0.6743

  Interaction Type:  

Host-Host interaction

Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-467-3p CIITA
miRBase
Accession/Entrez ID		 hsa-miR-467-3p 4261
Organism Homo sapiens Homo sapiens
Category miRNA mRNA
Alias - C2TA//CIITAIV//MHC2TA//NLRA

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR CIITA
chr16:11013768(+) A-I      intronic
chr16:11013744(+) A-I      intronic
chr16:11013737(+) A-I      intronic
chr16:11013734(+) A-I      intronic
chr16:10984273(+) A-I      intronic
chr16:11013776(+) A-I      intronic
chr16:11022225(+) A-I      3'UTR
chr16:11020572(+) A-I      3'UTR
chr16:10986777(+) A-I      intronic
chr16:10987501(+) A-I      intronic
chr16:10987513(+) A-I      intronic
chr16:10987961(+) A-I      intronic
chr16:11006218(+) A-I      intronic
chr16:11006223(+) A-I      intronic
chr16:11007191(+) A-I      intronic
chr16:11007308(+) A-I      intronic
chr16:10986589(+) A-I      intronic
chr16:10984353(+) A-I      intronic
chr16:10983597(+) A-I      intronic
chr16:10983556(+) A-I      intronic
chr16:10983550(+) A-I      intronic
chr16:10983502(+) A-I      intronic
chr16:10983477(+) A-I      intronic
chr16:10978437(+) A-I      intronic
chr16:10978429(+) A-I      intronic
chr16:10978427(+) A-I      intronic
chr16:10976373(+) A-I      intronic
chr16:10984333(+) A-I      intronic
chr16:11007579(+) A-I      intronic
chr16:10984283(+) A-I      intronic
chr16:10984205(+) A-I      intronic
chr16:10983598(+) A-I      intronic
chr16:10986637(+) A-I      intronic
chr16:10986612(+) A-I      intronic
chr16:10986776(+) A-I      intronic
chr16:11007370(+) A-I      intronic
chr16:11007418(+) A-I      intronic
chr16:11007613(+) A-I      intronic
chr16:11020524(+) A-I      3'UTR
chr16:11020497(+) A-I      3'UTR
chr16:11020510(+) A-I      3'UTR
chr16:11020515(+) A-I      3'UTR
chr16:11020421(+) A-I      3'UTR
chr16:11020523(+) A-I      3'UTR
chr16:11020563(+) A-I      3'UTR
chr16:11018352(+) A-I      3'UTR
chr16:11019215(+) A-I      3'UTR
chr16:11022383(+) A-I      3'UTR
chr16:11022345(+) A-I      3'UTR
chr16:11022215(+) A-I      3'UTR
chr16:11018342(+) A-I      3'UTR
chr16:11019402(+) A-I      3'UTR
chr16:11022206(+) A-I      3'UTR
chr16:11020589(+) A-I      3'UTR
chr16:11007301(+) A-I      intronic
chr16:11007542(+) A-I      intronic
chr16:11007271(+) A-I      intronic
chr16:10999440(+) A-I      intronic
chr16:10987898(+) A-I      intronic
chr16:11007609(+) A-I      intronic
chr16:11007624(+) A-I      intronic
chr16:11007608(+) A-I      intronic
chr16:11019216(+) A-I      3'UTR
chr16:11018367(+) A-I      3'UTR
chr16:11020498(+) A-I      3'UTR
chr16:11019264(+) A-I      3'UTR
chr16:11018118(+) A-I      3'UTR
chr16:11022409(+) A-I      3'UTR
chr16:10984244(+) A-I      intronic
chr16:10978296(+) A-I      intronic
chr16:10989589(+) A-I      NonSyn:Asp->Gly
chr16:11003731(+) A-I      intronic
chr16:10983408(+) A-I      intronic
chr16:11007272(+) A-I      intronic
chr16:11013491(+) A-I      intronic
chr16:10983470(+) A-I      intronic
chr16:11007311(+) A-I      intronic
chr16:10999363(+) A-I      intronic
chr16:11007541(+) A-I      intronic
chr16:11007433(+) A-I      intronic
chr16:11007687(+) A-I      intronic
chr16:11007568(+) A-I      intronic
chr16:11008987(+) A-I      intronic
chr16:11007378(+) A-I      intronic
chr16:11008982(+) A-I      intronic
chr16:10999862(+) A-I      intronic
chr16:11007677(+) A-I      intronic
chr16:10999362(+) A-I      intronic
chr16:11007651(+) A-I      intronic
chr16:10986636(+) A-I      intronic
chr16:11007235(+) A-I      intronic
chr16:11007763(+) A-I      intronic
chr16:10975112(+) A-I      intronic
chr16:10986580(+) A-I      intronic
chr16:10984364(+) A-I      intronic
chr16:11013492(+) A-I      intronic
chr16:10987944(+) A-I      intronic
chr16:10981590(+) A-I      intronic
chr16:11007233(+) A-I      intronic
chr16:11007236(+) A-I      intronic
chr16:10986588(+) A-I      intronic
chr16:10978295(+) A-I      intronic
chr16:10975093(+) A-I      intronic
chr16:10983396(+) A-I      intronic
chr16:10986660(+) A-I      intronic
chr16:10981446(+) A-I      intronic
chr16:11008972(+) A-I      intronic
chr16:11013729(+) A-I      intronic
chr16:11013732(+) A-I      intronic
chr16:11013743(+) A-I      intronic
chr16:11013772(+) A-I      intronic
chr16:10984287(+) A-I      intronic
chr16:11013716(+) A-I      intronic
chr16:11013733(+) A-I      intronic
chr16:11013764(+) A-I      intronic
chr16:11013728(+) A-I      intronic
chr16:11013526(+) A-I      intronic
chr16:11007753(+) A-I      intronic
chr16:10976663(+) A-I      intronic
chr16:11013527(+) A-I      intronic
chr16:11013773(+) A-I      intronic
chr16:11013612(+) A-I      intronic
chr16:11007519(+) A-I      intronic
chr16:11013634(+) A-I      intronic
chr16:11013506(+) A-I      intronic
chr16:11013709(+) A-I      intronic
chr16:11013517(+) A-I      intronic
chr16:11020578(+) A-I      3'UTR
chr16:11020581(+) A-I      3'UTR
chr16:11018312(+) A-I      3'UTR
chr16:11022263(+) A-I      3'UTR
chr16:11018279(+) A-I      3'UTR
chr16:11018324(+) A-I      3'UTR
chr16:11019263(+) A-I      3'UTR
chr16:11019419(+) A-I      3'UTR
chr16:11022250(+) A-I      3'UTR
chr16:11022331(+) A-I      3'UTR
chr16:11018220(+) A-I      3'UTR
chr16:11020583(+) A-I      3'UTR
chr16:11020478(+) A-I      3'UTR
chr16:11018290(+) A-I      3'UTR
chr16:11020434(+) A-I      3'UTR
chr16:11020459(+) A-I      3'UTR
chr16:11022214(+) A-I      3'UTR
chr16:11020501(+) A-I      3'UTR
chr16:11018230(+) A-I      3'UTR
chr16:11020462(+) A-I      3'UTR
chr16:11022249(+) A-I      3'UTR
chr16:11022376(+) A-I      3'UTR
chr16:11022328(+) A-I      3'UTR
chr16:11018299(+) A-I      3'UTR
chr16:11018232(+) A-I      3'UTR
chr16:11019276(+) A-I      3'UTR
chr16:11018191(+) A-I      3'UTR
chr16:11020598(+) A-I      3'UTR
chr16:11020502(+) A-I      3'UTR
chr16:11018256(+) A-I      3'UTR
chr16:11018240(+) A-I      3'UTR
chr16:11018273(+) A-I      3'UTR
chr16:11018310(+) A-I      3'UTR
chr16:11022275(+) A-I      3'UTR
chr16:11022245(+) A-I      3'UTR
chr16:11022246(+) A-I      3'UTR
chr16:11020595(+) A-I      3'UTR
chr16:11018270(+) A-I      3'UTR
Resource Symbol Editing Position Change SeqReg exReg PMID
DARNED CIITA
chr16:10989589(+) A-I exon CDS    15342557
chr16:10995933(+) A-I exon CDS    15342557
chr16:11002927(+) A-I exon CDS    15342557
chr16:11018118(+) A-I exon 3'UTR    15342557
chr16:11018220(+) A-I exon 3'UTR    15342557
chr16:11018230(+) A-I exon 3'UTR    15342557
chr16:11018232(+) A-I exon 3'UTR    15342557
chr16:11018240(+) A-I exon 3'UTR    15342557
chr16:11018270(+) A-I exon 3'UTR    15342557   //15258596
chr16:11018290(+) A-I exon 3'UTR    15342557   //15258596
chr16:11018299(+) A-I exon 3'UTR    15342557   //15258596
chr16:11018310(+) A-I exon 3'UTR    15342557   //15258596
chr16:11018324(+) A-I exon 3'UTR    15342557   //15258596
chr16:11013716(+) A-I intron -    22327324
chr16:11013732(+) A-I intron -    22327324
chr16:11013733(+) A-I intron -    22327324
chr16:11013716(+) A-G intron -    22484847
chr16:11013728(+) A-G intron -    22484847
chr16:11013729(+) A-G intron -    22484847
chr16:11013732(+) A-G intron -    22484847
chr16:11013733(+) A-G intron -    22484847
chr16:11013743(+) A-G intron -    22484847
chr16:11013764(+) A-G intron -    22484847
chr16:10999440(+) A-G intron -    22484847
chr16:11007608(+) A-G intron -    22484847
chr16:11007677(+) A-G intron -    22484847
chr16:11007687(+) A-G intron -    22484847

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase CIITA
chr16:10989249-10989250(+) m6A CDS//exon       -
chr16:10989537-10989538(+) m6A CDS//exon       -
chr16:10989596-10989597(+) m6A CDS//exon       -
chr16:10992530-10992531(+) m6A CDS//exon       -
chr16:10992535-10992536(+) m6A CDS//exon       -
chr16:10992553-10992554(+) m6A CDS//exon       -
chr16:10992580-10992581(+) m6A CDS//exon       -
chr16:10992791-10992792(+) m6A CDS//exon       -
chr16:10995934-10995935(+) m6A 3'UTR//CDS//exon//intron       -
chr16:10996025-10996026(+) m6A 3'UTR//CDS//exon//intron       -
chr16:10996560-10996561(+) m6A 3'UTR//CDS//exon       -
chr16:10996627-10996628(+) m6A CDS//exon       -
chr16:10997659-10997660(+) m6A CDS//exon       -
chr16:10997720-10997721(+) m6A CDS//exon       -
chr16:10997743-10997744(+) m6A CDS//exon       -
chr16:11000388-11000389(+) m6A CDS//exon//intron       -
chr16:11000491-11000492(+) m6A CDS//exon//intron       22575960
chr16:11000505-11000506(+) m6A CDS//exon//intron       22575960
chr16:11000585-11000586(+) m6A CDS//exon//intron       22575960
chr16:11000718-11000719(+) m6A CDS//exon//intron       -
chr16:11001123-11001124(+) m6A CDS//exon//intron       -
chr16:11001147-11001148(+) m6A CDS//exon//intron       -
chr16:11001265-11001266(+) m6A CDS//exon//intron       -
chr16:11001358-11001359(+) m6A CDS//exon//intron       22575960
chr16:11001381-11001382(+) m6A CDS//exon//intron       22575960
chr16:11001407-11001408(+) m6A CDS//exon//intron       22575960
chr16:11001537-11001538(+) m6A CDS//exon//intron       22575960
chr16:11001696-11001697(+) m6A CDS//exon//intron       22575960
chr16:11001746-11001747(+) m6A CDS//exon//intron       22575960
chr16:11001921-11001922(+) m6A CDS//exon//intron       22575960
chr16:11001933-11001934(+) m6A CDS//exon//intron       22575960
chr16:11001982-11001983(+) m6A CDS//exon//intron       -
chr16:11002031-11002032(+) m6A CDS//exon//intron       -
chr16:11002275-11002276(+) m6A 3'UTR//exon//intron       -
chr16:11002368-11002369(+) m6A 3'UTR//exon//intron       -
chr16:11002940-11002941(+) m6A CDS//exon//intron       -
chr16:11004064-11004065(+) m6A CDS//exon       -
chr16:11004094-11004095(+) m6A CDS//exon       -
chr16:11004104-11004105(+) m6A 3'UTR//CDS//exon       -
chr16:11009462-11009463(+) m6A 3'UTR//CDS//exon       -
chr16:11017882-11017883(+) m6A 3'UTR//exon       -
chr16:11017905-11017906(+) m6A 3'UTR//exon       -
chr16:11018001-11018002(+) m6A 3'UTR//exon       -
chr16:11018010-11018011(+) m6A 3'UTR//exon       -
chr16:11018113-11018114(+) m6A 3'UTR//exon       -
chr16:11018276-11018277(+) m6A 3'UTR//exon       -
chr16:11018311-11018312(+) m6A 3'UTR//exon       -
chr16:11018426-11018427(+) m6A 3'UTR//exon       -
chr16:11018459-11018460(+) m6A 3'UTR//exon       -
chr16:11018541-11018542(+) m6A 3'UTR//exon       22575960
chr16:11018613-11018614(+) m6A 3'UTR//exon       22575960
chr16:11018625-11018626(+) m6A 3'UTR//exon       22575960
chr16:11018650-11018651(+) m6A 3'UTR//exon       22575960
chr16:11022806-11022807(+) m6A 3'UTR//intron       27773535//22608085
chr16:11023011-11023012(+) m6A 3'UTR//intron       24284625//24209618//25456834//24981863//27773535//27371828//22575960//22608085
chr16:11023029-11023030(+) m6A 3'UTR//intron       24284625//24209618//25456834//24981863//27773535//27371828//22575960//22608085
chr16:11023045-11023046(+) m6A 3'UTR//intron       24284625//24209618//25456834//24981863//27773535//27371828//22575960//22608085
chr16:11023183-11023184(+) m6A 3'UTR//intron       24284625//24209618//25456834//24981863//27773535//27371828//22575960//22608085
chr16:11023204-11023205(+) m6A 3'UTR//intron       24284625//24209618//25456834//24981863//27773535//27371828//22575960//22608085
chr16:11023372-11023373(+) m6A 3'UTR//intron       24284625//24209618//25456834//24981863//27371828//22608085
chr16:11023378-11023379(+) m6A 3'UTR//intron       24284625//24209618//25456834//24981863//27371828//22608085
chr16:11023482-11023483(+) m6A 3'UTR//intron       27371828
chr16:11023488-11023489(+) m6A 3'UTR//intron       27371828

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate CIITA
Cytoplasm Nasopharyngeal carcinoma cells     20498841
Exosome Blood     -
Nucleolus K562 cells     -
Nucleus Nasopharyngeal carcinoma cells     20498841

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-467-3p
Interactor2: CIITA

Evidence Support:


Weak-Evidence MiRNA microarray//RNA-Seq
Prediction-Evidence microRNA.org//PITA//Targetscan
Support Database ViRBase

References:


PMID 30605755 Target region None
Source ViRBase Interactor1 expression Downregulation
Tissue or cell line A549 cells Interactor2 expression Upregulation
Description A. Relationships between miRNAs and inversely correlated mRNAs involved in the influenza A pathway.

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