Basic Information:

  VIRBase ID:  

HHID00092711

  Virus:  

Influenza A virus (H1N1)

  Host:  

Mus musculus

  Confidence Score:  

0.5711

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      mmu-miR-200a-3p:  MIMAT0000519          Ifnar2:  NM_001110498     

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Interactor Information:

	Interactor1	Interactor2
Symbol	mmu-miR-200a-3p	Ifnar2
miRBase Accession/Entrez ID	MIMAT0000519	15976
Organism	Mus musculus	Mus musculus
Category	miRNA	mRNA
Alias	-	AI747302//Ifn//Ifnar-2

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	Ifnar2	chr16:91372836-91372837(+) m6A 5'UTR       25412662 chr16:91372874-91372875(+) m6A 5'UTR       25412662//25569111 chr16:91372884-91372885(+) m6A 5'UTR       25412662//25569111 chr16:91372902-91372903(+) m6A 5'UTR       25412662//25569111 chr16:91373036-91373037(+) m6A 5'UTR       25412662 chr16:91373060-91373061(+) m6A 5'UTR       25412662 chr16:91383880-91383881(+) m6A 5'UTR       25412662 chr16:91388095-91388096(+) m6A CDS       22608085 chr16:91393787-91393788(+) m6A CDS       24981863//25569111 chr16:91393808-91393809(+) m6A CDS       24981863//25569111 chr16:91393822-91393823(+) m6A CDS       24981863//25569111 chr16:91399325-91399326(+) m6A CDS//intron       25456834//24981863//25569111 chr16:91403791-91403792(+) m6A 3'UTR//CDS       25683224//25456834//25412662//24981863//25569111//22608085//22575960 chr16:91403804-91403805(+) m6A 3'UTR//CDS       25683224//25456834//25412662//24981863//25569111//22608085//22575960 chr16:91403888-91403889(+) m6A 3'UTR//CDS       25683224//25456834//25412662//24981863//25569111//22608085//22575960 chr16:91403913-91403914(+) m6A 3'UTR//CDS       25683224//25456834//25412662//24981863//25569111//22608085//22575960 chr16:91404014-91404015(+) m6A 3'UTR//CDS       25683224//25456834//25412662//24981863//25569111//22608085//22575960 chr16:91404049-91404050(+) m6A 3'UTR//CDS       25683224//25456834//25412662//24981863//25569111//22608085//22575960 chr16:91404091-91404092(+) m6A 3'UTR//CDS       25683224//25456834//25412662//24981863//25569111//22608085//22575960 chr16:91404109-91404110(+) m6A 3'UTR//CDS       25683224//25456834//25412662//24981863//25569111//22608085//22575960 chr16:91404136-91404137(+) m6A 3'UTR//CDS       25683224//25456834//25412662//24981863//25569111//22608085//22575960 chr16:91404157-91404158(+) m6A 3'UTR//CDS       25683224//25456834//25412662//24981863//25569111//22608085//22575960 chr16:91404163-91404164(+) m6A 3'UTR//CDS       25683224//25456834//25412662//24981863//25569111//22608085//22575960 chr16:91404207-91404208(+) m6A 3'UTR//CDS       25683224//25456834//25412662//24981863//25569111//22608085//22575960 chr16:91404226-91404227(+) m6A 3'UTR//CDS       25683224//25456834//25412662//24981863//25569111//22608085//22575960 chr16:91404258-91404259(+) m6A 3'UTR//CDS       25683224//25456834//25412662//24981863//25569111//22608085//22575960 chr16:91404268-91404269(+) m6A 3'UTR//CDS       25683224//25456834//25412662//24981863//25569111//22608085//22575960 chr16:91404289-91404290(+) m6A 3'UTR//CDS       25683224//25456834//25412662//24981863//25569111//22608085//22575960 chr16:91404294-91404295(+) m6A 3'UTR//CDS       25683224//25456834//25412662//24981863//25569111//22608085//22575960 chr16:91404336-91404337(+) m6A 3'UTR//CDS       25683224//25456834//25412662//24981863//25569111//22608085//22575960 chr16:91404364-91404365(+) m6A 3'UTR//CDS       25683224//25456834//25412662//24981863//25569111//22608085//22575960 chr16:91404512-91404513(+) m6A 3'UTR       25683224//25456834//25412662//24981863//25569111//22608085//22575960 chr16:91404520-91404521(+) m6A 3'UTR       25683224//25456834//25412662//24981863//25569111//22608085//22575960 chr16:91404671-91404672(+) m6A 3'UTR       25456834//24981863//25569111//22608085 chr16:91404769-91404770(+) m6A 3'UTR       25412662//24981863//25456834//25569111//22608085 chr16:91404793-91404794(+) m6A 3'UTR       25683224//25412662//24981863//25456834//25569111 chr16:91404806-91404807(+) m6A 3'UTR       25683224//25412662//24981863//25456834//25569111 chr16:91405112-91405113(+) m6A 3'UTR       25456834//24981863//25569111 chr16:91405193-91405194(+) m6A 3'UTR       25683224//25456834//24981863//25569111 chr16:91405228-91405229(+) m6A 3'UTR       25683224//25456834//24981863//25569111//22608085 chr16:91405254-91405255(+) m6A 3'UTR       25683224//25456834//25412662//24981863//25569111//22608085 chr16:91405293-91405294(+) m6A 3'UTR       25683224//25456834//25412662//24981863//25569111//22608085 chr16:91405304-91405305(+) m6A 3'UTR       25683224//25456834//25412662//24981863//25569111//22608085 chr16:91405313-91405314(+) m6A 3'UTR       25683224//25456834//25412662//24981863//25569111//22608085 chr16:91405324-91405325(+) m6A 3'UTR       25683224//25456834//25412662//24981863//25569111//22608085 chr16:91405363-91405364(+) m6A 3'UTR       25683224//25412662//24981863//25456834//25569111//22608085 chr16:91405392-91405393(+) m6A 3'UTR       25683224//25412662//24981863//25456834//25569111

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	mmu-miR-200a-3p	Exosome Serum     28160157

Interaction Network (The top 100 interactions):

Interactor1: mmu-miR-200a-3p
Interactor2: Ifnar2

Evidence Support:

Weak-Evidence	Microarray
Prediction-Evidence	miRanda
Support Database	ViRBase

References:

PMID	20071585	Target region	None
Source	ViRBase	Interactor1 expression	Downregulation
Tissue or cell line	MDCK cells	Interactor2 expression	None
Description	Our analysis of microRNA targets indicated that the type I IFN pathway was subject to microRNA-mediated regulation, since key genes in this pathway, such as IFNAR1 and STAT2, are direct targets of miR-200a, and their expression was inversely correlated with the expression of this microRNA (Fig.4).