Detail Information

Basic Information:


  VIRBase ID:  

HHID00092660

  Virus:  

Influenza A virus (A/WSN/1933(H1N1))

  Host:  

Homo sapiens

  Confidence Score:  

0.5908

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-1275:           DPYSL3:      

      *It may take a few minutes to display results.

Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-1275 DPYSL3
miRBase
Accession/Entrez ID		 MIMAT0005929 1809
Organism Homo sapiens Homo sapiens
Category miRNA mRNA
Alias - CRMP-4//CRMP4//DRP-3//DRP3//LCRMP//ULIP//ULIP-1

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-1275
rs372458638 chr6:34000019    A/AAAACC
rs377188203 chr6:34000023    C/T
rs557928121 chr6:34000019    A/T
rs758811783 chr6:34000022    G/A
rs761034364 chr6:34000017    AGAC/A
rs370361021 chr6:34000029    C/A
rs370361021 chr6:34000029    C/T
rs374728385 chr6:34000032    C/A
rs374728385 chr6:34000032    C/G
rs747378297 chr6:34000028    C/T
rs772691699 chr6:34000033    A/G

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR DPYSL3
chr5:146881292(-) A-I      intronic
chr5:146881269(-) A-I      intronic
chr5:146868723(-) A-I      intronic
chr5:146836396(-) A-I      intronic
chr5:146882886(-) A-I      intronic
chr5:146882304(-) A-I      intronic
chr5:146882288(-) A-I      intronic
chr5:146844579(-) A-I      intronic
chr5:146881224(-) A-I      intronic
chr5:146836400(-) A-I      intronic
chr5:146844544(-) A-I      intronic
chr5:146836399(-) A-I      intronic
chr5:146881238(-) A-I      intronic
chr5:146881293(-) A-I      intronic
chr5:146836282(-) A-I      intronic
chr5:146882296(-) A-I      intronic
chr5:146813590(-) A-I      intronic
chr5:146844608(-) A-I      intronic
chr5:146880065(-) A-I      intronic
chr5:146880077(-) A-I      intronic
Resource Symbol Editing Position Change SeqReg exReg PMID
DARNED DPYSL3
chr5:146868748(-) A-I intron -    19478186
chr5:146868749(-) A-I intron -    19478186
chr5:146868750(-) A-I intron -    19478186

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase DPYSL3
chr5:146771219-146771220(-) m6A 3'UTR       24981863
chr5:146771352-146771353(-) m6A 3'UTR       27773535
chr5:146773242-146773243(-) m6A 3'UTR       24981863//27773535
chr5:146773271-146773272(-) m6A 3'UTR       24981863//27773535
chr5:146773348-146773349(-) m6A 3'UTR       27773535
chr5:146833127-146833128(-) m6A CDS//exon//intron       24209618//25456834//24981863//27773536
chr5:146833346-146833347(-) m6A 5'UTR//intron       25456834//24981863
chr5:146833405-146833406(-) m6A 5'UTR//intron       25456834//24981863
chr5:146833410-146833411(-) m6A 5'UTR//intron       25456834//24981863
chr5:146833748-146833749(-) m6A 5'UTR//intron       25456834
chr5:146833765-146833766(-) m6A 5'UTR//intron       25456834
chr5:146852861-146852862(-) m6A exon//intron       24209618
chr5:146852891-146852892(-) m6A exon//intron       24209618//27773536
chr5:146889044-146889045(-) m6A CDS//exon       24209618//27773536
chr5:146889059-146889060(-) m6A CDS//exon       24209618//25456834//27773536
chr5:146889170-146889171(-) m6A CDS       24209618//25456834//24981863//27773536
chr5:146889231-146889232(-) m6A CDS       24209618//25456834//27773536
chr5:146889341-146889342(-) m6A CDS       24209618//24981863//27773536
chr5:146889395-146889396(-) m6A CDS       24209618//25456834//24981863//27773536
chr5:146889423-146889424(-) m6A 5'UTR       24209618//25456834//24981863//27773536
chr5:146889448-146889449(-) m6A 5'UTR       25456834//24981863//27773536
chr5:146889573-146889574(-) m6A 5'UTR       24981863//27773536

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-1275
Exosome Breast cancer cell line (MCF-7)     20976003
Exosome B cell lymphoma cell lines|EBV-transformed lymphoblastoid B cells     25242326
Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     -
Microvesicle Seminal plasma     23539611
Microvesicle Colon cancer cell line (LIM1863)|Mesenchymal stem cells     -
Mitochondrion HeLa cells     27396686
Mitochondrion HeLa cells     27563705
Mitochondrion Cell line (HeLa)     21695135
Mitochondrion Cell line (HEK-293|HeLa)     22984580
Nucleolus HeLa cells     23940654
DPYSL3
Cytosol HeLa-S3 cells     -
Exosome Blood     -

Related Drug Information:


Resource Symbol Drug Name PubChem
ID		 Function Link  
RNAInter hsa-miR-1275
Gemcitabine 60750 Drug interaction    RC00007825
Vincristine 5978 Drug interaction    RC00007823
Eloxatine 5310940 Drug interaction    RC00007826
Paclitaxel 36314 Drug interaction    RC00007824
5-Fluorouracil 3385 Drug interaction    RC00007822
cis-Diaminedichloroplatinum 2767 Drug interaction    RC00007821
Marine fungal metabolite 1386A - Drug interaction    RC00007827
Resource Symbol Drug Name PubChem ID
RNAactDrug hsa-miR-1275
l-685,458       5479543

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-1275
Interactor2: DPYSL3

Evidence Support:


Weak-Evidence Microarray
Prediction-Evidence miRWalk//Targetscan
Support Database ViRBase

References:


PMID 22822053 Target region 3'UTR
Source ViRBase Interactor1 expression Upregulation
Tissue or cell line A549 cells//BEAS-2B cells//Vero cells Interactor2 expression Downregulation
Description Gene expression profiling identified 26 cellular mRNAs targeted by these miRNAs, including IRAK1, MAPK3, and other components of innate immune signaling systems.

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