Detail Information

Basic Information:


  VIRBase ID:  

HHID00092614

  Virus:  

Influenza A virus (A/WSN/1933(H1N1))

  Host:  

Homo sapiens

  Confidence Score:  

0.8589

  Interaction Type:  

Host-Host interaction

Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-1975 IFNB1
miRBase
Accession/Entrez ID		 hsa-miR-1975 3456
Organism Homo sapiens Homo sapiens
Category miRNA mRNA
Alias - IFB//IFF//IFN-beta//IFNB

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase IFNB1
chr9:21077198-21077199(-) m6A 3'UTR       27773535
chr9:21077273-21077274(-) m6A 3'UTR       27773535
chr9:21077278-21077279(-) m6A 3'UTR       27773535
chr9:21077308-21077309(-) m6A CDS       27773535
chr9:21077328-21077329(-) m6A CDS       27773535
chr9:21077347-21077348(-) m6A CDS       27773535
chr9:21077375-21077376(-) m6A CDS       27773535
chr9:21077592-21077593(-) m6A CDS       27773535
chr9:21077611-21077612(-) m6A CDS       27773535
chr9:21077695-21077696(-) m6A CDS       27773535
chr9:21077704-21077705(-) m6A CDS       27773535

Related Drug Information:


Resource Symbol Drug Name PubChem ID
RNAactDrug hsa-miR-1975
l-685,458       5479543

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-1975
Interactor2: IFNB1

Evidence Support:


Strong-Evidence RT-qPCR
Weak-Evidence Small RNA sequencing
Support Database ViRBase

References:


PMID 31416454 Target region None
Source ViRBase Interactor1 expression None
Tissue or cell line None Interactor2 expression None
Description These results imply that activation of IFNB gene expression may account for the effect of hsa-miR-1975. Together, these data demonstrated that hsa-miR-1975 induces interferon production, suggesting its role in host cell's antiviral response.

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