Detail Information

Basic Information:


  VIRBase ID:  

HHID00092610

  Virus:  

Influenza A virus (A/WSN/1933(H1N1))

  Host:  

Homo sapiens

  Confidence Score:  

0.9526

  Interaction Type:  

Host-Host interaction

Interactor Information:


Interactor1 Interactor2
Symbol lnc-MxA IFNB1
miRBase
Accession/Entrez ID		 lnc-MxA 3456
Organism Homo sapiens Homo sapiens
Category lncRNA mRNA
Alias - IFB//IFF//IFN-beta//IFNB

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase IFNB1
chr9:21077198-21077199(-) m6A 3'UTR       27773535
chr9:21077273-21077274(-) m6A 3'UTR       27773535
chr9:21077278-21077279(-) m6A 3'UTR       27773535
chr9:21077308-21077309(-) m6A CDS       27773535
chr9:21077328-21077329(-) m6A CDS       27773535
chr9:21077347-21077348(-) m6A CDS       27773535
chr9:21077375-21077376(-) m6A CDS       27773535
chr9:21077592-21077593(-) m6A CDS       27773535
chr9:21077611-21077612(-) m6A CDS       27773535
chr9:21077695-21077696(-) m6A CDS       27773535
chr9:21077704-21077705(-) m6A CDS       27773535

Interaction Network (The top 100 interactions):


Interactor1: lnc-MxA
Interactor2: IFNB1

Evidence Support:


Strong-Evidence Luciferase reporter assay//RT-qPCR//Western blot
Support Database ViRBase

References:


PMID 31434735 Target region None
Source ViRBase Interactor1 expression Upregulation
Tissue or cell line 293T cells Interactor2 expression Downregulation
Description The data showed that the levels of the NP and the M1 proteins in the lnc-MxA knockdown cells were lower than those in the control cells (Fig. 2E).

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