Basic Information:

  VIRBase ID:  

HHID00092503

  Virus:  

Influenza A virus (A/swine/Guangxi/3861/2011(H1N1))

  Host:  

Homo sapiens

  Confidence Score:  

0.6743

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-1915-3p:  MIMAT0007892          CXCL8:  NM_000584     

      *It may take a few minutes to display results.

Interactor Information:

	Interactor1	Interactor2
Symbol	hsa-miR-1915-3p	CXCL8
miRBase Accession/Entrez ID	MIMAT0007892	3576
Organism	Homo sapiens	Homo sapiens
Category	miRNA	mRNA
Alias	-	GCP-1//GCP1//IL8//LECT//LUCT//LYNAP//MDNCF//MONAP//NAF//NAP-1//NAP1//SCYB8

ncRNA SNP information:

Resource	Symbol	SNP ID	SNP Position	Ref/Alt
miRNASNP-v3	hsa-miR-1915-3p	rs1319660164 chr10:21496576    C/T rs1335396985 chr10:21496581    C/G rs1359100620 chr10:21496582    G/A rs1416262346 chr10:21496578    C/A rs540277336 chr10:21496579    G/A rs540277336 chr10:21496579    G/C rs983068182 chr10:21496591    T/G

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	CXCL8	chr4:74606289-74606290(+) m6A 5'UTR//exon       24981863//26404942 chr4:74606299-74606300(+) m6A 5'UTR//exon       24981863//26404942 chr4:74606324-74606325(+) m6A 5'UTR//exon       24981863//26404942//27773535 chr4:74606341-74606342(+) m6A 5'UTR//exon       24981863//26404942//27773535 chr4:74606354-74606355(+) m6A 5'UTR//exon       24981863//26404942//27773535 chr4:74606373-74606374(+) m6A 5'UTR//exon       24981863//26404942//27773535 chr4:74607286-74607287(+) m6A CDS//exon       27773535 chr4:74607308-74607309(+) m6A CDS//exon       27773535 chr4:74607319-74607320(+) m6A CDS//exon       26404942//27773535 chr4:74607346-74607347(+) m6A CDS//exon       26404942//27773535 chr4:74607367-74607368(+) m6A CDS//exon       26404942//27773535 chr4:74607434-74607435(+) m6A exon//intron       26404942 chr4:74608331-74608332(+) m6A 3'UTR       27773535 chr4:74608370-74608371(+) m6A 3'UTR       27773535 chr4:74608413-74608414(+) m6A 3'UTR       27773535 chr4:74608510-74608511(+) m6A 3'UTR       26404942//27773535 chr4:74608579-74608580(+) m6A 3'UTR       26404942//27773535

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	hsa-miR-1915-3p	Exosome Pooled sera     27278097 Exosome Breast cancer cell line (MCF-7)     20976003 Exosome Breast cancer cell lines (MCF-7|MDA-MB-231)     24468161 Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     - Microvesicle Seminal plasma     23539611 Microvesicle Cell lines(GBM46|GBM8|HaCaT|K562|MCF-10A|MCF-7|MGG75)|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocytes     -
	CXCL8	Exosome Blood     -

Interaction Network (The top 100 interactions):

Interactor1: hsa-miR-1915-3p
Interactor2: CXCL8

Evidence Support:

Weak-Evidence	MiRNA microarray//RNA-Seq
Prediction-Evidence	microRNA.org//PITA//Targetscan
Support Database	ViRBase

References:

PMID	30605755	Target region	None
Source	ViRBase	Interactor1 expression	Downregulation
Tissue or cell line	A549 cells	Interactor2 expression	Upregulation
Description	A. Relationships between miRNAs and inversely correlated mRNAs involved in the influenza A pathway.