Detail Information

Basic Information:


  VIRBase ID:  

HHID00092425

  Virus:  

Influenza A virus (A/Puerto Rico/8/1934(H1N1))

  Host:  

Homo sapiens

  Confidence Score:  

0.6002

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-501-3p:           HRAS:      

      *It may take a few minutes to display results.

Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-501-3p HRAS
miRBase
Accession/Entrez ID		 MIMAT0004774 3265
Organism Homo sapiens Homo sapiens
Category miRNA mRNA
Alias - C-BAS/HAS//C-H-RAS//C-HA-RAS1//CTLO//H-RASIDX//HAMSV//HRAS1//p21ras//RASH1

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-501-3p
rs112489955 chrX:50009781    G/A
rs112489955 chrX:50009781    G/T
rs1557182212 chrX:50009793    T/C
rs376696825 chrX:50009787    G/A
rs376696825 chrX:50009787    G/T
rs781947379 chrX:50009780    C/T
rs782814071 chrX:50009784    C/T
rs149912461 chrX:50009773    A/G
rs1557182197 chrX:50009774    T/C
rs367629841 chrX:50009778    C/T
rs782056456 chrX:50009775    G/A

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase HRAS
chr11:532326-532327(-) m6A 3'UTR//exon       24284625//24209618//25456834//24981863//28052920//27773535//27371828//27773536//22575960//22608085
chr11:532346-532347(-) m6A 3'UTR//exon       24284625//24209618//25456834//24981863//28052920//27773535//27371828//27773536//22575960//22608085
chr11:532356-532357(-) m6A 3'UTR//exon       24284625//24209618//25456834//24981863//28052920//27773535//27371828//27773536//22575960//22608085
chr11:532381-532382(-) m6A 3'UTR//exon       24284625//24209618//25456834//24981863//28052920//27773535//27371828//27773536//22575960//22608085
chr11:532404-532405(-) m6A 3'UTR//exon       24284625//24209618//25456834//24981863//28052920//27773535//27371828//27773536//22575960//22608085
chr11:532509-532510(-) m6A 3'UTR//exon       24284625//24209618//25456834//24981863//28052920//27773535//27371828//27773536//22575960//22608085
chr11:532620-532621(-) m6A 3'UTR//exon//intron       24284625//24209618//24981863//27773535//27371828//27773536//22575960//22608085
chr11:532690-532691(-) m6A 3'UTR//CDS//exon//intron       24209618//22608085
chr11:533304-533305(-) m6A CDS//exon//intron       24209618
chr11:533314-533315(-) m6A CDS//exon//intron       24209618
chr11:533324-533325(-) m6A CDS//exon//intron       24209618
chr11:533460-533461(-) m6A CDS//exon       24209618//27371828//27773536
chr11:533472-533473(-) m6A CDS//exon       24209618//27371828//27773536
chr11:533507-533508(-) m6A CDS//exon       24209618//27371828//27773536
chr11:533555-533556(-) m6A CDS//exon       24209618//27371828//27773536
chr11:533588-533589(-) m6A CDS//exon       24209618//27371828//27773536
chr11:533780-533781(-) m6A CDS//exon       27371828//27773536
chr11:533849-533850(-) m6A CDS//exon       24209618//27773535//22575960
chr11:533894-533895(-) m6A CDS//exon       24209618//27773535//22575960
chr11:534245-534246(-) m6A CDS//exon       24209618//27773535
chr11:534349-534350(-) m6A 5'UTR//exon       24209618//24981863
chr11:534362-534363(-) m6A 5'UTR//exon       24209618//24981863
chr11:535490-535491(-) m6A 5'UTR//intron       24209618
chr11:536874-536875(-) m6A exon       24981863
chr11:536883-536884(-) m6A exon       24981863
chr11:536990-536991(-) m6A exon       24981863
chr11:537035-537036(-) m6A exon       24981863
chr11:537043-537044(-) m6A exon       24981863

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-501-3p
Exosome Primary dendritic cells     21505438
Exosome Plasma     23663360
Exosome Human mast cell line (HMC-1)     24009880
Exosome Blood     -
Microvesicle Seminal plasma     23539611
Microvesicle Colon cancer cell line (LIM1863)|Fibroblasts|Mesenchymal stem cells     -
Mitochondrion Myotube     27396686
Mitochondrion Skeletal muscle cells     27563705
Mitochondrion Skeletal muscle myoblasts     21637849
Mitochondrion Cell line (HEK-293|HeLa)     22984580
HRAS
Cytosol Human myelogenous leukemia cell line (K-562)     21613539
Exosome Blood     -
Nucleolus K562 cells     -
Ribosome Colon cancer cells     24393600

Related Drug Information:


Resource Symbol Drug Name PubChem ID PMID
NoncoRNA hsa-miR-501-3p
Cisplatin 5702198       30221699

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-501-3p
Interactor2: HRAS

Evidence Support:


Weak-Evidence MiRNA microarray
Prediction-Evidence microRNA.org//PITA//Targetscan
Support Database ViRBase

References:


PMID 29059211 Target region 3'UTR
Source ViRBase Interactor1 expression Downregulation
Tissue or cell line HUVECs Interactor2 expression None
Description The differential miRNAs and their target genes in the above pathways were concluded in Table S1 and Table S2.

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