Basic Information:

  VIRBase ID:  

HHID00092276

  Virus:  

Influenza A virus (A/Puerto Rico/8/1934(H1N1))

  Host:  

Homo sapiens

  Confidence Score:  

0.5711

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-30a-3p:  MIMAT0000088          SLC7A6:  NM_003983     

      *It may take a few minutes to display results.

Interactor Information:

	Interactor1	Interactor2
Symbol	hsa-miR-30a-3p	SLC7A6
miRBase Accession/Entrez ID	MIMAT0000088	9057
Organism	Homo sapiens	Homo sapiens
Category	miRNA	mRNA
Alias	-	LAT-2//LAT3//y+LAT-2

ncRNA SNP information:

Resource	Symbol	SNP ID	SNP Position	Ref/Alt
miRNASNP-v3	hsa-miR-30a-3p	rs149150037 chr6:71403567    G/A rs149150037 chr6:71403567    G/C rs370184894 chr6:71403566    C/A rs370184894 chr6:71403566    C/T rs552541514 chr6:71403558    C/G rs745605208 chr6:71403563    ATCCG/A rs746505574 chr6:71403557    G/A rs746505574 chr6:71403557    G/T rs746965145 chr6:71403554    GCT/G rs750918072 chr6:71403564    T/C rs765735953 chr6:71403560    A/T rs770865356 chr6:71403559    A/AC rs776574456 chr6:71403560    A/AAGCTGGAGT rs368070339 chr6:71403571    G/A rs769702885 chr6:71403570    TG/T rs775921090 chr6:71403574    AGCC/A rs781617967 chr6:71403573    A/T

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	SLC7A6	chr16:68330078(+) A-I      intronic chr16:68299676(+) A-I      intronic chr16:68313535(+) A-I      intronic chr16:68313506(+) A-I      intronic chr16:68321164(+) A-I      intronic chr16:68321133(+) A-I      intronic chr16:68320915(+) A-I      intronic chr16:68316795(+) A-I      intronic chr16:68316782(+) A-I      intronic chr16:68316601(+) A-I      intronic chr16:68316262(+) A-I      intronic chr16:68316208(+) A-I      intronic chr16:68313608(+) A-I      intronic chr16:68313590(+) A-I      intronic chr16:68313583(+) A-I      intronic chr16:68313581(+) A-I      intronic chr16:68313571(+) A-I      intronic chr16:68313497(+) A-I      intronic chr16:68313453(+) A-I      intronic chr16:68313227(+) A-I      intronic chr16:68313194(+) A-I      intronic chr16:68313178(+) A-I      intronic chr16:68313141(+) A-I      intronic chr16:68313124(+) A-I      intronic chr16:68313019(+) A-I      intronic chr16:68311631(+) A-I      intronic chr16:68311175(+) A-I      intronic chr16:68311164(+) A-I      intronic chr16:68311091(+) A-I      intronic chr16:68311090(+) A-I      intronic chr16:68310863(+) A-I      intronic chr16:68310802(+) A-I      intronic chr16:68310651(+) A-I      intronic chr16:68309404(+) A-I      intronic chr16:68309312(+) A-I      intronic chr16:68309252(+) A-I      intronic chr16:68306121(+) A-I      intronic chr16:68306115(+) A-I      intronic chr16:68305958(+) A-I      intronic chr16:68305893(+) A-I      intronic chr16:68305846(+) A-I      intronic chr16:68305834(+) A-I      intronic chr16:68305798(+) A-I      intronic chr16:68305727(+) A-I      intronic chr16:68299935(+) A-I      intronic chr16:68318781(+) A-I      intronic chr16:68320925(+) A-I      intronic chr16:68313200(+) A-I      intronic chr16:68303536(+) A-I      intronic chr16:68305343(+) A-I      intronic chr16:68313080(+) A-I      intronic chr16:68305308(+) A-I      intronic chr16:68313653(+) A-I      intronic chr16:68310783(+) A-I      intronic chr16:68303887(+) A-I      intronic chr16:68322746(+) A-I      intronic chr16:68313170(+) A-I      intronic chr16:68309313(+) A-I      intronic chr16:68321020(+) A-I      intronic chr16:68316290(+) A-I      intronic chr16:68316225(+) A-I      intronic chr16:68319813(+) A-I      intronic chr16:68313230(+) A-I      intronic chr16:68300042(+) A-I      intronic chr16:68319766(+) A-I      intronic chr16:68303523(+) A-I      intronic chr16:68309342(+) A-I      intronic chr16:68316725(+) A-I      intronic chr16:68321155(+) A-I      intronic chr16:68313467(+) A-I      intronic chr16:68313130(+) A-I      intronic chr16:68311070(+) A-I      intronic chr16:68313614(+) A-I      intronic chr16:68305326(+) A-I      intronic chr16:68305928(+) A-I      intronic chr16:68309377(+) A-I      intronic chr16:68313465(+) A-I      intronic chr16:68305164(+) A-I      intronic chr16:68310741(+) A-I      intronic chr16:68306284(+) A-I      intronic chr16:68316239(+) A-I      intronic chr16:68309309(+) A-I      intronic chr16:68311129(+) A-I      intronic chr16:68312989(+) A-I      intronic chr16:68311587(+) A-I      intronic chr16:68311015(+) A-I      intronic chr16:68306277(+) A-I      intronic chr16:68310672(+) A-I      intronic chr16:68311013(+) A-I      intronic chr16:68310645(+) A-I      intronic chr16:68314843(+) A-I      intronic chr16:68310850(+) A-I      intronic chr16:68319806(+) A-I      intronic chr16:68321157(+) A-I      intronic chr16:68310623(+) A-I      intronic chr16:68310853(+) A-I      intronic chr16:68316723(+) A-I      intronic chr16:68316540(+) A-I      intronic chr16:68316737(+) A-I      intronic chr16:68313090(+) A-I      intronic chr16:68320974(+) A-I      intronic chr16:68303582(+) A-I      intronic chr16:68316293(+) A-I      intronic chr16:68313689(+) A-I      intronic chr16:68313461(+) A-I      intronic chr16:68303895(+) A-I      intronic chr16:68316243(+) A-I      intronic chr16:68305847(+) A-I      intronic chr16:68305779(+) A-I      intronic chr16:68306343(+) A-I      intronic chr16:68310847(+) A-I      intronic chr16:68303923(+) A-I      intronic chr16:68327057(+) A-I      intronic chr16:68310717(+) A-I      intronic chr16:68312984(+) A-I      intronic chr16:68311803(+) A-I      intronic chr16:68320966(+) A-I      intronic chr16:68309244(+) A-I      intronic chr16:68319785(+) A-I      intronic chr16:68303596(+) A-I      intronic chr16:68311046(+) A-I      intronic chr16:68316238(+) A-I      intronic chr16:68310743(+) A-I      intronic chr16:68311177(+) A-I      intronic chr16:68309334(+) A-I      intronic chr16:68326448(+) A-I      intronic chr16:68312040(+) A-I      intronic chr16:68306257(+) A-I      intronic chr16:68320980(+) A-I      intronic chr16:68303607(+) A-I      intronic chr16:68305785(+) A-I      intronic chr16:68310706(+) A-I      intronic chr16:68306315(+) A-I      intronic chr16:68311069(+) A-I      intronic chr16:68319983(+) A-I      intronic chr16:68319982(+) A-I      intronic chr16:68312967(+) A-I      intronic chr16:68306218(+) A-I      intronic chr16:68313134(+) A-I      intronic chr16:68322685(+) A-I      intronic chr16:68305170(+) A-I      intronic chr16:68310740(+) A-I      intronic chr16:68319742(+) A-I      intronic chr16:68310827(+) A-I      intronic chr16:68311997(+) A-I      intronic chr16:68316682(+) A-I      intronic chr16:68306292(+) A-I      intronic chr16:68306055(+) A-I      intronic chr16:68320955(+) A-I      intronic chr16:68319720(+) A-I      intronic chr16:68313568(+) A-I      intronic chr16:68316286(+) A-I      intronic chr16:68310759(+) A-I      intronic chr16:68311896(+) A-I      intronic chr16:68311170(+) A-I      intronic chr16:68309315(+) A-I      intronic chr16:68303578(+) A-I      intronic chr16:68310791(+) A-I      intronic chr16:68319909(+) A-I      intronic chr16:68321081(+) A-I      intronic chr16:68316660(+) A-I      intronic chr16:68310646(+) A-I      intronic chr16:68319726(+) A-I      intronic chr16:68321010(+) A-I      intronic chr16:68313029(+) A-I      intronic chr16:68322614(+) A-I      intronic chr16:68305822(+) A-I      intronic chr16:68311476(+) A-I      intronic chr16:68303514(+) A-I      intronic chr16:68312983(+) A-I      intronic chr16:68309423(+) A-I      intronic chr16:68319919(+) A-I      intronic chr16:68313639(+) A-I      intronic chr16:68305784(+) A-I      intronic chr16:68323179(+) A-I      intronic chr16:68313000(+) A-I      intronic chr16:68321143(+) A-I      intronic chr16:68306062(+) A-I      intronic chr16:68306194(+) A-I      intronic chr16:68319853(+) A-I      intronic chr16:68313567(+) A-I      intronic chr16:68311488(+) A-I      intronic chr16:68309243(+) A-I      intronic chr16:68311043(+) A-I      intronic chr16:68305729(+) A-I      intronic chr16:68313644(+) A-I      intronic chr16:68319889(+) A-I      intronic chr16:68303810(+) A-I      intronic chr16:68311131(+) A-I      intronic chr16:68310742(+) A-I      intronic chr16:68312120(+) A-I      intronic chr16:68313210(+) A-I      intronic chr16:68319892(+) A-I      intronic chr16:68310736(+) A-I      intronic chr16:68311009(+) A-I      intronic chr16:68305980(+) A-I      intronic chr16:68316216(+) A-I      intronic chr16:68320998(+) A-I      intronic chr16:68321022(+) A-I      intronic chr16:68311123(+) A-I      intronic chr16:68327272(+) A-I      intronic chr16:68312132(+) A-I      intronic chr16:68313622(+) A-I      intronic chr16:68313147(+) A-I      intronic chr16:68313006(+) A-I      intronic chr16:68311107(+) A-I      intronic chr16:68327064(+) A-I      intronic chr16:68306229(+) A-I      intronic chr16:68313677(+) A-I      intronic chr16:68311579(+) A-I      intronic chr16:68306203(+) A-I      intronic chr16:68311116(+) A-I      intronic chr16:68313702(+) A-I      intronic chr16:68313125(+) A-I      intronic chr16:68309378(+) A-I      intronic chr16:68313559(+) A-I      intronic chr16:68311119(+) A-I      intronic chr16:68320913(+) A-I      intronic chr16:68303729(+) A-I      intronic chr16:68316217(+) A-I      intronic chr16:68318842(+) A-I      intronic chr16:68310751(+) A-I      intronic chr16:68311959(+) A-I      intronic chr16:68305338(+) A-I      intronic chr16:68311051(+) A-I      intronic chr16:68313542(+) A-I      intronic chr16:68311960(+) A-I      intronic chr16:68311173(+) A-I      intronic chr16:68311611(+) A-I      intronic chr16:68317949(+) A-I      intronic chr16:68316194(+) A-I      intronic chr16:68309450(+) A-I      intronic chr16:68306361(+) A-I      intronic chr16:68317978(+) A-I      intronic chr16:68313220(+) A-I      intronic chr16:68320981(+) A-I      intronic chr16:68313625(+) A-I      intronic chr16:68309241(+) A-I      intronic chr16:68318788(+) A-I      intronic chr16:68321070(+) A-I      intronic chr16:68316783(+) A-I      intronic chr16:68306179(+) A-I      intronic chr16:68311200(+) A-I      intronic chr16:68311059(+) A-I      intronic chr16:68305769(+) A-I      intronic chr16:68307804(+) A-I      5'UTR chr16:68307767(+) A-I      5'UTR

Resource	Symbol	Editing Position	Change	SeqReg	exReg	PMID
DARNED	SLC7A6	chr16:68310783(+) A-I intron -    22327324 chr16:68319853(+) A-I intron -    22327324 chr16:68317978(+) A-G intron -    22484847 chr16:68318078(+) T-C intron -    22484847 chr16:68300923(+) T-C intron -    22484847 chr16:68306203(+) A-G intron -    22484847 chr16:68306257(+) A-G intron -    22484847 chr16:68306277(+) A-G intron -    22484847 chr16:68307767(+) A-G exon 5'UTR    22484847 chr16:68309376(+) T-C intron -    22484847 chr16:68310751(+) A-G intron -    22484847 chr16:68310783(+) A-G intron -    22484847 chr16:68310850(+) A-G intron -    22484847 chr16:68311051(+) A-G intron -    22484847 chr16:68311070(+) A-G intron -    22484847 chr16:68316238(+) A-G intron -    22484847 chr16:68316243(+) A-G intron -    22484847 chr16:68318762(+) C-T intron -    22484847 chr16:68319747(+) T-C intron -    22484847 chr16:68319853(+) A-G intron -    22484847 chr16:68320925(+) A-G intron -    22484847 chr16:68320974(+) A-G intron -    22484847 chr16:68321143(+) A-G intron -    22484847

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	SLC7A6	chr16:68308603-68308604(+) m6A 5'UTR       24284625 chr16:68308619-68308620(+) m6A 5'UTR       24284625 chr16:68308740-68308741(+) m6A CDS       24284625 chr16:68308935-68308936(+) m6A CDS//intron       24284625//22608085 chr16:68330648-68330649(+) Y 3'UTR//CDS//exon       26075521 chr16:68331222-68331223(+) m6A 3'UTR//CDS//exon       24284625//24209618//25456834//24981863//27773535//22608085 chr16:68331293-68331294(+) m6A 3'UTR//exon       24284625//24209618//25456834//24981863//22575960//22608085 chr16:68331393-68331394(+) m6A 3'UTR//intron       24284625//24981863//22608085 chr16:68331939-68331940(+) m6A 3'UTR//intron       24981863//22608085 chr16:68332034-68332035(+) m6A 3'UTR//intron       24284625//24981863//22575960//22608085 chr16:68332042-68332043(+) m6A 3'UTR//intron       24284625//24981863//22575960//22608085 chr16:68332087-68332088(+) m6A 3'UTR//intron       24284625//24981863//27773535//22575960//22608085 chr16:68332109-68332110(+) m6A 3'UTR//intron       24284625//24981863//27773535//22575960//22608085 chr16:68332160-68332161(+) m6A 3'UTR//intron       24284625//24981863//27773535//22608085 chr16:68332177-68332178(+) m6A 3'UTR//intron       24284625//24981863//27773535//22608085 chr16:68332233-68332234(+) m6A 3'UTR//intron       24284625//22608085 chr16:68332293-68332294(+) m6A 3'UTR//intron       24284625 chr16:68332305-68332306(+) m6A 3'UTR//intron       24284625 chr16:68332352-68332353(+) m6A 3'UTR//intron       24284625//24209618 chr16:68332435-68332436(+) m6A 3'UTR       24284625//24209618//25456834//24981863//27371828//22575960//22608085 chr16:68332517-68332518(+) m6A 3'UTR       24284625//24209618//25456834//24981863//27371828//22575960//22608085 chr16:68332550-68332551(+) m6A 3'UTR       24284625//24209618//25456834//24981863//22575960//22608085 chr16:68332733-68332734(+) m6A 3'UTR       24284625//24209618//24981863//26404942//22575960//22608085 chr16:68332758-68332759(+) m6A 3'UTR       24284625//24209618//24981863//22575960//22608085 chr16:68333344-68333345(+) m6A 3'UTR       27773535 chr16:68333795-68333796(+) m6A 3'UTR       27773535 chr16:68333844-68333845(+) m6A 3'UTR       24981863//27773535 chr16:68334362-68334363(+) m6A 3'UTR       27773535 chr16:68334448-68334449(+) m6A 3'UTR       27773535 chr16:68334545-68334546(+) m6A 3'UTR       27773535 chr16:68334912-68334913(+) m6A 3'UTR       24284625 chr16:68334946-68334947(+) m6A 3'UTR       24284625//22575960 chr16:68334999-68335000(+) m6A 3'UTR       24284625//24981863//27773535//22575960//22608085 chr16:68335090-68335091(+) m6A 3'UTR       24284625//24209618//25456834//24981863//26404942//27773535//22575960//22608085 chr16:68335125-68335126(+) m6A 3'UTR       24284625//24209618//25456834//24981863//26404942//27773535//22575960//22608085 chr16:68335154-68335155(+) m6A 3'UTR       24284625//24209618//25456834//24981863//26404942//27773535//22575960//22608085 chr16:68335163-68335164(+) m6A 3'UTR       24284625//24209618//25456834//24981863//26404942//27773535//27371828//22575960//22608085 chr16:68335173-68335174(+) m6A 3'UTR       24284625//24209618//25456834//24981863//26404942//27773535//27371828//22575960//22608085 chr16:68335215-68335216(+) m6A 3'UTR       24284625//24209618//25456834//24981863//26404942//27773535//27371828//22575960//22608085 chr16:68335647-68335648(+) m6A 3'UTR       27773535

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	hsa-miR-30a-3p	Exosome Brain tissue     23382797 Exosome Plasma     23663360 Exosome Breast milk|Endothelial cells|Epithelial cells|Tongue tissue     - Microvesicle Seminal plasma     23539611 Microvesicle Follicular fluid     23666971 Microvesicle Serum     24797360 Microvesicle Fibroblasts|Mesenchymal stem cells|Urine     - Mitochondrion Skeletal muscle myoblasts     21637849 Mitochondrion Cell line (HEK-293|HeLa)     22984580
	SLC7A6	Chromatin K562 cells     - Cytosol HCC cell line (HepG2)|HeLa-S3 cells|K562 cells     - Exosome Blood     - Membrane HCC cell line (HepG2)     - Nucleolus K562 cells     - Nucleoplasm K562 cells     - Nucleus K562 cells     - Ribosome HEK-293 cells     22199352

Related Drug Information:

Resource	Symbol	Drug Name	PubChem ID	Function	Link
RNAInter	hsa-miR-30a-3p	Sorafenib 216239 Drug interaction    RC00000903

Resource	Symbol	Drug Name	PubChem ID	PMID
NoncoRNA	hsa-miR-30a-3p	Imatinib 5291       25349971

Interaction Network (The top 100 interactions):

Interactor1: hsa-miR-30a-3p
Interactor2: SLC7A6

Evidence Support:

Weak-Evidence	RNA-Seq
Prediction-Evidence	DIANA
Support Database	ViRBase

References:

PMID	31985023	Target region	None
Source	ViRBase	Interactor1 expression	None
Tissue or cell line	None	Interactor2 expression	None
Description	In the predication analysis, NEAT1 targeted 144 mRNAs through miRNAs (Table III).