Detail Information

Basic Information:


  VIRBase ID:  

HHID00092260

  Virus:  

Influenza A virus (A/Puerto Rico/8/1934(H1N1))

  Host:  

Homo sapiens

  Confidence Score:  

0.8808

  Interaction Type:  

Host-Host interaction

Interactor Information:


Interactor1 Interactor2
Symbol lncRNA-155 IFNB1
miRBase
Accession/Entrez ID		 lncRNA-155 3456
Organism Homo sapiens Homo sapiens
Category lncRNA mRNA
Alias - IFB//IFF//IFN-beta//IFNB

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase IFNB1
chr9:21077198-21077199(-) m6A 3'UTR       27773535
chr9:21077273-21077274(-) m6A 3'UTR       27773535
chr9:21077278-21077279(-) m6A 3'UTR       27773535
chr9:21077308-21077309(-) m6A CDS       27773535
chr9:21077328-21077329(-) m6A CDS       27773535
chr9:21077347-21077348(-) m6A CDS       27773535
chr9:21077375-21077376(-) m6A CDS       27773535
chr9:21077592-21077593(-) m6A CDS       27773535
chr9:21077611-21077612(-) m6A CDS       27773535
chr9:21077695-21077696(-) m6A CDS       27773535
chr9:21077704-21077705(-) m6A CDS       27773535

Interaction Network (The top 100 interactions):


Interactor1: lncRNA-155
Interactor2: IFNB1

Evidence Support:


Strong-Evidence RT-PCR//RT-qPCR
Support Database ViRBase

References:


PMID 31045320 Target region None
Source ViRBase Interactor1 expression Upregulation
Tissue or cell line A549 cells Interactor2 expression None
Description We observed that silencing lncRNA‐155 resulted in a marked downregulation of IFN‐beta and Mx1 mRNA levels in IAV‐infected cells as compared with the control (Figure 3e).

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