Detail Information

Basic Information:


  VIRBase ID:  

HHID00092109

  Virus:  

Influenza A virus (A/Mexico/InDRE4487/2009(H1N1))

  Host:  

Homo sapiens

  Confidence Score:  

0.8847

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-138-1-3p:           STC1:      

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Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-138-1-3p STC1
miRBase
Accession/Entrez ID		 MIMAT0004607 6781
Organism Homo sapiens Homo sapiens
Category miRNA mRNA
Alias - STC

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-138-1-3p
rs1215016527 chr3:44114288    C/T
rs759234321 chr3:44114292    G/A
rs759234321 chr3:44114292    G/C
rs770499543 chr3:44114276    T/C
rs773680447 chr3:44114278    C/A
rs892673276 chr3:44114281    C/T

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase STC1
chr8:23701976-23701977(-) m6A 3'UTR       24981863
chr8:23701983-23701984(-) m6A 3'UTR       24981863
chr8:23701994-23701995(-) m6A 3'UTR       24981863
chr8:23702325-23702326(-) m6A CDS       24284625//25456834//24981863
chr8:23702343-23702344(-) m6A CDS       24284625//25456834//24981863
chr8:23702413-23702414(-) m6A CDS       24284625//25456834//24981863//26404942//27773536
chr8:23702431-23702432(-) m6A CDS       24284625//25456834//24981863//26404942//27773536
chr8:23702487-23702488(-) m6A CDS       24284625//25456834//24981863//26404942
chr8:23702508-23702509(-) m6A CDS       24284625//25456834//24981863//26404942
chr8:23702540-23702541(-) m6A CDS       25456834//24981863
chr8:23708883-23708884(-) m6A CDS       -
chr8:23712066-23712067(-) m6A 5'UTR       27773536

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-138-1-3p
Exosome Plasma     23663360
Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     -
Microvesicle Fibroblasts|Mesenchymal stem cells     -
STC1
Exosome Blood     -

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-138-1-3p
Interactor2: STC1

Evidence Support:


Strong-Evidence qRT-PCR
Weak-Evidence Microarray
Prediction-Evidence miRanda
Support Database ViRBase

References:


PMID 22438559 Target region None
Source ViRBase Interactor1 expression Upregulation
Tissue or cell line A549 cells Interactor2 expression Downregulation
Description Fig 3 The 8-hpi network shows a number of deregulated miRNAs and their predicted targets, including miR-766, that is consistently upregulated throughout infection with H1N1.

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