Basic Information:

  VIRBase ID:  

HHID00092015

  Virus:  

Influenza A virus (A/California/07/2009(H1N1))

  Host:  

Homo sapiens

  Confidence Score:  

0.6002

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-147b-3p:  MIMAT0004928          MYL9:  NM_006097     

      *It may take a few minutes to display results.

Interactor Information:

	Interactor1	Interactor2
Symbol	hsa-miR-147b-3p	MYL9
miRBase Accession/Entrez ID	MIMAT0004928	10398
Organism	Homo sapiens	Homo sapiens
Category	miRNA	mRNA
Alias	-	LC20//MLC-2C//MLC2//MRLC1//MYRL2

ncRNA SNP information:

Resource	Symbol	SNP ID	SNP Position	Ref/Alt
miRNASNP-v3	hsa-miR-147b-3p	rs1200410442 chr15:45433107    A/T rs752984903 chr15:45433111    C/T rs754846973 chr15:45433098    G/T rs757376786 chr15:45433118    T/C rs1053956663 chr15:45433104    G/A rs1262406913 chr15:45433103    CG/C rs1347541319 chr15:45433102    G/A rs376183261 chr15:45433101    T/G rs753817843 chr15:45433103    C/T

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	MYL9	chr20:35175750(+) A-I      intronic chr20:35173712(+) A-I      intronic chr20:35174056(+) A-I      intronic chr20:35175752(+) A-I      intronic chr20:35175759(+) A-I      intronic chr20:35175760(+) A-I      intronic chr20:35175764(+) A-I      intronic chr20:35175768(+) A-I      intronic chr20:35175772(+) A-I      intronic chr20:35175773(+) A-I      intronic chr20:35175782(+) A-I      intronic chr20:35175807(+) A-I      intronic chr20:35175810(+) A-I      intronic chr20:35175315(+) A-I      intronic chr20:35175811(+) A-I      intronic chr20:35176024(+) A-I      intronic chr20:35176036(+) A-I      intronic chr20:35175763(+) A-I      intronic chr20:35176045(+) A-I      intronic chr20:35176046(+) A-I      intronic chr20:35176050(+) A-I      intronic chr20:35174037(+) A-I      intronic chr20:35175739(+) A-I      intronic chr20:35175730(+) A-I      intronic chr20:35175731(+) A-I      intronic chr20:35175735(+) A-I      intronic chr20:35175740(+) A-I      intronic chr20:35173700(+) A-I      intronic chr20:35175271(+) A-I      intronic chr20:35175112(+) A-I      intronic chr20:35175074(+) A-I      intronic chr20:35175061(+) A-I      intronic chr20:35175039(+) A-I      intronic chr20:35174219(+) A-I      intronic chr20:35174148(+) A-I      intronic chr20:35174146(+) A-I      intronic chr20:35174084(+) A-I      intronic chr20:35175744(+) A-I      intronic chr20:35175106(+) A-I      intronic chr20:35175093(+) A-I      intronic chr20:35175087(+) A-I      intronic chr20:35175049(+) A-I      intronic chr20:35175043(+) A-I      intronic chr20:35175042(+) A-I      intronic chr20:35175037(+) A-I      intronic chr20:35174310(+) A-I      intronic chr20:35174273(+) A-I      intronic chr20:35174251(+) A-I      intronic chr20:35174244(+) A-I      intronic chr20:35174243(+) A-I      intronic chr20:35174212(+) A-I      intronic chr20:35174172(+) A-I      intronic chr20:35174171(+) A-I      intronic chr20:35174167(+) A-I      intronic chr20:35174155(+) A-I      intronic chr20:35175113(+) A-I      intronic chr20:35173651(+) A-I      intronic chr20:35173654(+) A-I      intronic chr20:35173715(+) A-I      intronic chr20:35173721(+) A-I      intronic chr20:35173722(+) A-I      intronic chr20:35173723(+) A-I      intronic chr20:35173734(+) A-I      intronic chr20:35173737(+) A-I      intronic chr20:35173738(+) A-I      intronic chr20:35173741(+) A-I      intronic chr20:35173743(+) A-I      intronic chr20:35173747(+) A-I      intronic chr20:35173748(+) A-I      intronic chr20:35173749(+) A-I      intronic chr20:35173750(+) A-I      intronic chr20:35173758(+) A-I      intronic chr20:35173789(+) A-I      intronic chr20:35173806(+) A-I      intronic chr20:35175274(+) A-I      intronic chr20:35175290(+) A-I      intronic chr20:35175287(+) A-I      intronic chr20:35175276(+) A-I      intronic chr20:35173740(+) A-I      intronic chr20:35174087(+) A-I      intronic chr20:35173820(+) A-I      intronic chr20:35173828(+) A-I      intronic chr20:35173895(+) A-I      intronic chr20:35174070(+) A-I      intronic chr20:35175265(+) A-I      intronic chr20:35175262(+) A-I      intronic chr20:35175261(+) A-I      intronic chr20:35175233(+) A-I      intronic chr20:35175222(+) A-I      intronic chr20:35175202(+) A-I      intronic chr20:35175187(+) A-I      intronic chr20:35175179(+) A-I      intronic chr20:35175178(+) A-I      intronic chr20:35175154(+) A-I      intronic chr20:35175130(+) A-I      intronic chr20:35175115(+) A-I      intronic chr20:35174079(+) A-I      intronic chr20:35174180(+) A-I      intronic chr20:35174272(+) A-I      intronic chr20:35174181(+) A-I      intronic chr20:35174156(+) A-I      intronic chr20:35174173(+) A-I      intronic chr20:35173713(+) A-I      intronic chr20:35174078(+) A-I      intronic chr20:35173753(+) A-I      intronic chr20:35174179(+) A-I      intronic chr20:35174170(+) A-I      intronic chr20:35174185(+) A-I      intronic chr20:35173821(+) A-I      intronic chr20:35174182(+) A-I      intronic chr20:35174176(+) A-I      intronic chr20:35175165(+) A-I      intronic chr20:35175142(+) A-I      intronic chr20:35175196(+) A-I      intronic chr20:35173637(+) A-I      intronic chr20:35173646(+) A-I      intronic

Resource	Symbol	Editing Position	Change	SeqReg	exReg	PMID
DARNED	MYL9	chr20:35170667(+) A-I intron -    15342557 chr20:35173637(+) A-I intron -    15258596 chr20:35173645(+) A-I intron -    15342557   //15258596 chr20:35173646(+) A-I intron -    15342557   //15258596 chr20:35173667(+) A-I intron -    15258596 chr20:35173713(+) A-I intron -    15342557   //15258596 chr20:35173753(+) A-I intron -    15342557 chr20:35173779(+) A-I intron -    15342557 chr20:35173785(+) A-I intron -    15342557 chr20:35173821(+) A-I intron -    15342557 chr20:35175142(+) A-I intron -    15258596 chr20:35175152(+) A-I intron -    15258596 chr20:35175165(+) A-I intron -    15258596 chr20:35175193(+) A-I intron -    15258596 chr20:35175196(+) A-I intron -    15258596 chr20:35175213(+) A-I intron -    15258596 chr20:35175283(+) A-I intron -    15258596

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	MYL9	chr20:35169905-35169906(+) m6A 5'UTR       24284625//25456834//24981863 chr20:35173314-35173315(+) m6A CDS       24284625//25456834//24981863//22575960 chr20:35173417-35173418(+) m6A CDS       24284625//24981863//22575960 chr20:35173444-35173445(+) m6A CDS       24284625//24981863 chr20:35176440-35176441(+) m6A CDS//intron       24284625 chr20:35177791-35177792(+) m6A 3'UTR       24284625//22575960 chr20:35177884-35177885(+) m6A 3'UTR       24284625//25456834//22575960 chr20:35177898-35177899(+) m6A 3'UTR       24284625//25456834//22575960 chr20:35177917-35177918(+) m6A 3'UTR       24284625//25456834//22575960 chr20:35178025-35178026(+) m6A 3'UTR       24284625//25456834//22575960 chr20:35178176-35178177(+) m6A 3'UTR       24284625//24981863//22575960 chr20:35178213-35178214(+) m6A 3'UTR       24284625//24981863 chr20:35179578-35179579(+) m6A 3'UTR       - chr20:35179604-35179605(+) m6A 3'UTR       - chr20:35179672-35179673(+) m6A 3'UTR       - chr20:35179689-35179690(+) m6A 3'UTR       - chr20:35179703-35179704(+) m6A 3'UTR       - chr20:35179712-35179713(+) m6A 3'UTR       - chr20:35179733-35179734(+) m6A 3'UTR       -

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	hsa-miR-147b-3p	Exosome Plasma     23663360 Microvesicle Colon cancer cell line (LIM1863)|Fibroblasts|Mesenchymal stem cells     -
	MYL9	Cytosol Human myelogenous leukemia cell line (K-562)     21613539 Exosome Blood     -

Interaction Network (The top 100 interactions):

Interactor1: hsa-miR-147b-3p
Interactor2: MYL9

Evidence Support:

Weak-Evidence	MiRNA microarray
Prediction-Evidence	microRNA.org//PITA//Targetscan
Support Database	ViRBase

References:

PMID	29059211	Target region	3'UTR
Source	ViRBase	Interactor1 expression	Downregulation
Tissue or cell line	HUVECs	Interactor2 expression	None
Description	The differential miRNAs and their target genes in the above pathways were concluded in Table S1 and Table S2.