Detail Information

Basic Information:


  VIRBase ID:  

HHID00092013

  Virus:  

Influenza A virus (A/California/07/2009(H1N1))

  Host:  

Homo sapiens

  Confidence Score:  

0.6002

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-193b-5p:           HRAS:      

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Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-193b-5p HRAS
miRBase
Accession/Entrez ID		 MIMAT0004767 3265
Organism Homo sapiens Homo sapiens
Category miRNA mRNA
Alias - C-BAS/HAS//C-H-RAS//C-HA-RAS1//CTLO//H-RASIDX//HAMSV//HRAS1//p21ras//RASH1

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-193b-5p
rs1267267411 chr16:14303980    C/T
rs1282181138 chr16:14303999    TG/T
rs749491315 chr16:14303998    A/T
rs778011174 chr16:14303994    C/G
rs778011174 chr16:14303994    C/T
rs937569726 chr16:14303992    G/A
rs1178664690 chr16:14303984    G/A
rs769824339 chr16:14303981    G/C
rs890264882 chr16:14303983    G/A

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase HRAS
chr11:532326-532327(-) m6A 3'UTR//exon       24284625//24209618//25456834//24981863//28052920//27773535//27371828//27773536//22575960//22608085
chr11:532346-532347(-) m6A 3'UTR//exon       24284625//24209618//25456834//24981863//28052920//27773535//27371828//27773536//22575960//22608085
chr11:532356-532357(-) m6A 3'UTR//exon       24284625//24209618//25456834//24981863//28052920//27773535//27371828//27773536//22575960//22608085
chr11:532381-532382(-) m6A 3'UTR//exon       24284625//24209618//25456834//24981863//28052920//27773535//27371828//27773536//22575960//22608085
chr11:532404-532405(-) m6A 3'UTR//exon       24284625//24209618//25456834//24981863//28052920//27773535//27371828//27773536//22575960//22608085
chr11:532509-532510(-) m6A 3'UTR//exon       24284625//24209618//25456834//24981863//28052920//27773535//27371828//27773536//22575960//22608085
chr11:532620-532621(-) m6A 3'UTR//exon//intron       24284625//24209618//24981863//27773535//27371828//27773536//22575960//22608085
chr11:532690-532691(-) m6A 3'UTR//CDS//exon//intron       24209618//22608085
chr11:533304-533305(-) m6A CDS//exon//intron       24209618
chr11:533314-533315(-) m6A CDS//exon//intron       24209618
chr11:533324-533325(-) m6A CDS//exon//intron       24209618
chr11:533460-533461(-) m6A CDS//exon       24209618//27371828//27773536
chr11:533472-533473(-) m6A CDS//exon       24209618//27371828//27773536
chr11:533507-533508(-) m6A CDS//exon       24209618//27371828//27773536
chr11:533555-533556(-) m6A CDS//exon       24209618//27371828//27773536
chr11:533588-533589(-) m6A CDS//exon       24209618//27371828//27773536
chr11:533780-533781(-) m6A CDS//exon       27371828//27773536
chr11:533849-533850(-) m6A CDS//exon       24209618//27773535//22575960
chr11:533894-533895(-) m6A CDS//exon       24209618//27773535//22575960
chr11:534245-534246(-) m6A CDS//exon       24209618//27773535
chr11:534349-534350(-) m6A 5'UTR//exon       24209618//24981863
chr11:534362-534363(-) m6A 5'UTR//exon       24209618//24981863
chr11:535490-535491(-) m6A 5'UTR//intron       24209618
chr11:536874-536875(-) m6A exon       24981863
chr11:536883-536884(-) m6A exon       24981863
chr11:536990-536991(-) m6A exon       24981863
chr11:537035-537036(-) m6A exon       24981863
chr11:537043-537044(-) m6A exon       24981863

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-193b-5p
Exosome Jurkat-derived T cell line (J77cl20)     21505438
Exosome Plasma     23663360
Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     -
Microvesicle Seminal plasma     23539611
Microvesicle Follicular fluid     23666971
Microvesicle Fibroblasts|Mesenchymal stem cells|Urine     -
Mitochondrion Skeletal muscle cells     27563705
Mitochondrion Skeletal muscle myoblasts     21637849
Mitochondrion Cell line (HEK-293|HeLa)     22984580
HRAS
Cytosol Human myelogenous leukemia cell line (K-562)     21613539
Exosome Blood     -
Nucleolus K562 cells     -
Ribosome Colon cancer cells     24393600

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-193b-5p
Interactor2: HRAS

Evidence Support:


Weak-Evidence MiRNA microarray
Prediction-Evidence microRNA.org//PITA//Targetscan
Support Database ViRBase

References:


PMID 29059211 Target region 3'UTR
Source ViRBase Interactor1 expression None
Tissue or cell line HUVECs Interactor2 expression None
Description The differential miRNAs and their target genes in the above pathways were concluded in Table S1 and Table S2.

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