Detail Information

Basic Information:


  VIRBase ID:  

HHID00092009

  Virus:  

Influenza A virus (A/California/07/2009(H1N1))

  Host:  

Homo sapiens

  Confidence Score:  

0.6002

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-92a-1-5p:           HRAS:      

      *It may take a few minutes to display results.

Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-92a-1-5p HRAS
miRBase
Accession/Entrez ID		 MIMAT0004507 3265
Organism Homo sapiens Homo sapiens
Category miRNA mRNA
Alias - C-BAS/HAS//C-H-RAS//C-HA-RAS1//CTLO//H-RASIDX//HAMSV//HRAS1//p21ras//RASH1

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-92a-1-5p
rs1418785003 chr13:91351346    T/C
rs72631821 chr13:91351334    C/G
rs72631821 chr13:91351334    C/T
rs778492035 chr13:91351342    A/G
rs9589207 chr13:91351335    G/A
rs9589207 chr13:91351335    G/C
rs887397729 chr13:91351327    T/C

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase HRAS
chr11:532326-532327(-) m6A 3'UTR//exon       24284625//24209618//25456834//24981863//28052920//27773535//27371828//27773536//22575960//22608085
chr11:532346-532347(-) m6A 3'UTR//exon       24284625//24209618//25456834//24981863//28052920//27773535//27371828//27773536//22575960//22608085
chr11:532356-532357(-) m6A 3'UTR//exon       24284625//24209618//25456834//24981863//28052920//27773535//27371828//27773536//22575960//22608085
chr11:532381-532382(-) m6A 3'UTR//exon       24284625//24209618//25456834//24981863//28052920//27773535//27371828//27773536//22575960//22608085
chr11:532404-532405(-) m6A 3'UTR//exon       24284625//24209618//25456834//24981863//28052920//27773535//27371828//27773536//22575960//22608085
chr11:532509-532510(-) m6A 3'UTR//exon       24284625//24209618//25456834//24981863//28052920//27773535//27371828//27773536//22575960//22608085
chr11:532620-532621(-) m6A 3'UTR//exon//intron       24284625//24209618//24981863//27773535//27371828//27773536//22575960//22608085
chr11:532690-532691(-) m6A 3'UTR//CDS//exon//intron       24209618//22608085
chr11:533304-533305(-) m6A CDS//exon//intron       24209618
chr11:533314-533315(-) m6A CDS//exon//intron       24209618
chr11:533324-533325(-) m6A CDS//exon//intron       24209618
chr11:533460-533461(-) m6A CDS//exon       24209618//27371828//27773536
chr11:533472-533473(-) m6A CDS//exon       24209618//27371828//27773536
chr11:533507-533508(-) m6A CDS//exon       24209618//27371828//27773536
chr11:533555-533556(-) m6A CDS//exon       24209618//27371828//27773536
chr11:533588-533589(-) m6A CDS//exon       24209618//27371828//27773536
chr11:533780-533781(-) m6A CDS//exon       27371828//27773536
chr11:533849-533850(-) m6A CDS//exon       24209618//27773535//22575960
chr11:533894-533895(-) m6A CDS//exon       24209618//27773535//22575960
chr11:534245-534246(-) m6A CDS//exon       24209618//27773535
chr11:534349-534350(-) m6A 5'UTR//exon       24209618//24981863
chr11:534362-534363(-) m6A 5'UTR//exon       24209618//24981863
chr11:535490-535491(-) m6A 5'UTR//intron       24209618
chr11:536874-536875(-) m6A exon       24981863
chr11:536883-536884(-) m6A exon       24981863
chr11:536990-536991(-) m6A exon       24981863
chr11:537035-537036(-) m6A exon       24981863
chr11:537043-537044(-) m6A exon       24981863

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-92a-1-5p
Exosome Breast milk     22211110
Exosome Plasma     23663360
Exosome B cell lymphoma cell lines|EBV-transformed lymphoblastoid B cells     25242326
Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     -
Microvesicle Colon cancer cell line (LIM1863)|Fibroblasts|Mesenchymal stem cells     -
Mitochondrion Skeletal muscle myoblasts     21637849
Mitochondrion Cell line (HEK-293|HeLa)     22984580
HRAS
Cytosol Human myelogenous leukemia cell line (K-562)     21613539
Exosome Blood     -
Nucleolus K562 cells     -
Ribosome Colon cancer cells     24393600

Related Drug Information:


Resource Symbol Drug Name PubChem
ID		 Function Link  
RNAInter hsa-miR-92a-1-5p
Curcumin 969516 Drug interaction    RC00006826
Diethylstilbestrol 448537 Drug interaction    RC00006825
cis-Diaminedichloroplatinum 2767 Drug interaction    RC00006824
N-(3-(5-Chloro-1H-pyrrolo[2,3-b]pyridine-3-carbonyl)-2,4-difluorophenyl)propane-1-sulfonamide 24180719 Drug interaction    RC00006827
Resource Symbol Drug Name PubChem ID PMID
NoncoRNA hsa-miR-92a-1-5p
Cisplatin 5702198       26676926
N-(3-(5-Chloro-1H-pyrrolo[2,3-b]pyridine-3-carbonyl)-2,4-difluorophenyl)propane-1-sulfonamide 24180719       26456124

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-92a-1-5p
Interactor2: HRAS

Evidence Support:


Weak-Evidence MiRNA microarray
Prediction-Evidence microRNA.org//PITA//Targetscan
Support Database ViRBase

References:


PMID 29059211 Target region 3'UTR
Source ViRBase Interactor1 expression None
Tissue or cell line HUVECs Interactor2 expression None
Description The differential miRNAs and their target genes in the above pathways were concluded in Table S1 and Table S2.

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