Detail Information

Basic Information:


  VIRBase ID:  

HHID00091976

  Virus:  

Influenza A virus (A/California/07/2009(H1N1))

  Host:  

Homo sapiens

  Confidence Score:  

0.6002

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-138-5p:           ROCK2:      

      *It may take a few minutes to display results.

Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-138-5p ROCK2
miRBase
Accession/Entrez ID		 MIMAT0000430 9475
Organism Homo sapiens Homo sapiens
Category miRNA mRNA
Alias - ROCK-II

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-138-5p
rs1159226412 chr3:44114256    G/A
rs1331169318 chr3:44114250    C/A
rs1331169318 chr3:44114250    C/T
rs1466470291 chr3:44114249    T/A
rs748499444 chr3:44114243    T/C
rs1285034653 chr16:56858546    G/A
rs1389589086 chr16:56858539    G/A
rs1395610282 chr16:56858535    T/C
rs749468995 chr16:56858548    C/G
rs755213420 chr16:56858549    G/A
rs755213420 chr16:56858549    G/T

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR ROCK2
chr2:11411360(-) A-I      intronic
chr2:11321978(-) A-I      3'UTR
chr2:11321960(-) A-I      3'UTR
chr2:11321958(-) A-I      3'UTR
chr2:11425915(-) A-I      intronic
chr2:11425871(-) A-I      intronic
chr2:11321941(-) A-I      3'UTR
chr2:11328347(-) A-I      intronic
chr2:11328342(-) A-I      intronic
chr2:11411306(-) A-I      intronic
chr2:11411333(-) A-I      intronic
chr2:11411331(-) A-I      intronic
chr2:11411364(-) A-I      intronic
chr2:11411363(-) A-I      intronic
chr2:11411326(-) A-I      intronic
chr2:11434095(-) A-I      intronic
chr2:11409522(-) A-I      intronic
chr2:11411324(-) A-I      intronic
chr2:11411355(-) A-I      intronic
chr2:11411321(-) A-I      intronic
chr2:11411354(-) A-I      intronic
chr2:11411353(-) A-I      intronic
chr2:11411348(-) A-I      intronic
chr2:11411347(-) A-I      intronic
chr2:11411343(-) A-I      intronic
chr2:11411334(-) A-I      intronic
chr2:11321975(-) A-I      3'UTR
chr2:11411372(-) A-I      intronic
chr2:11478253(-) A-I      intronic
chr2:11425697(-) A-I      intronic
chr2:11425773(-) A-I      intronic
chr2:11425805(-) A-I      intronic
chr2:11425319(-) A-I      intronic
chr2:11425302(-) A-I      intronic
chr2:11425226(-) A-I      intronic
chr2:11425223(-) A-I      intronic
chr2:11422329(-) A-I      intronic
chr2:11422314(-) A-I      intronic
chr2:11434161(-) A-I      intronic
chr2:11435022(-) A-I      intronic
chr2:11435078(-) A-I      intronic
chr2:11435081(-) A-I      intronic
chr2:11435090(-) A-I      intronic
chr2:11422310(-) A-I      intronic
chr2:11422202(-) A-I      intronic
chr2:11435204(-) A-I      intronic
chr2:11408045(-) A-I      intronic
chr2:11409421(-) A-I      intronic
chr2:11409446(-) A-I      intronic
chr2:11409455(-) A-I      intronic
chr2:11409906(-) A-I      intronic
chr2:11409982(-) A-I      intronic
chr2:11415226(-) A-I      intronic
chr2:11415937(-) A-I      intronic
chr2:11418876(-) A-I      intronic
chr2:11418845(-) A-I      intronic
chr2:11418831(-) A-I      intronic
chr2:11418824(-) A-I      intronic
chr2:11418807(-) A-I      intronic
chr2:11435880(-) A-I      intronic
chr2:11389294(-) A-I      intronic
chr2:11388079(-) A-I      intronic
chr2:11384614(-) A-I      intronic
chr2:11378959(-) A-I      intronic
chr2:11372352(-) A-I      intronic
chr2:11360554(-) A-I      intronic
chr2:11346063(-) A-I      intronic
chr2:11360475(-) A-I      intronic
chr2:11360448(-) A-I      intronic
chr2:11360181(-) A-I      intronic
chr2:11359513(-) A-I      intronic
chr2:11359443(-) A-I      intronic
chr2:11359421(-) A-I      intronic
chr2:11352206(-) A-I      intronic
chr2:11352193(-) A-I      intronic
chr2:11352062(-) A-I      intronic
chr2:11346086(-) A-I      intronic
chr2:11346072(-) A-I      intronic
chr2:11478064(-) A-I      intronic
chr2:11441865(-) A-I      intronic
chr2:11329985(-) A-I      intronic
chr2:11328882(-) A-I      intronic
chr2:11467968(-) A-I      intronic
chr2:11325692(-) A-I      intronic
chr2:11325772(-) A-I      intronic
chr2:11360250(-) A-I      intronic
chr2:11328812(-) A-I      intronic
chr2:11328861(-) A-I      intronic
chr2:11328855(-) A-I      intronic
chr2:11328846(-) A-I      intronic
chr2:11476487(-) A-I      intronic
chr2:11477826(-) A-I      intronic
chr2:11477927(-) A-I      intronic
chr2:11328373(-) A-I      intronic
chr2:11425876(-) A-I      intronic
chr2:11328515(-) A-I      intronic
chr2:11328509(-) A-I      intronic
chr2:11328429(-) A-I      intronic
chr2:11476508(-) A-I      intronic
chr2:11330077(-) A-I      intronic
chr2:11464433(-) A-I      intronic
chr2:11328487(-) A-I      intronic
chr2:11328400(-) A-I      intronic
chr2:11389186(-) A-I      intronic
chr2:11328482(-) A-I      intronic
chr2:11359389(-) A-I      intronic
chr2:11329925(-) A-I      intronic
chr2:11418967(-) A-I      intronic
chr2:11407936(-) A-I      intronic
chr2:11345991(-) A-I      intronic
chr2:11422355(-) A-I      intronic
chr2:11328309(-) A-I      intronic
chr2:11425796(-) A-I      intronic
chr2:11330023(-) A-I      intronic
chr2:11425947(-) A-I      intronic
chr2:11329141(-) A-I      intronic
chr2:11359829(-) A-I      intronic
chr2:11415963(-) A-I      intronic
chr2:11328374(-) A-I      intronic
chr2:11418963(-) A-I      intronic
chr2:11330045(-) A-I      intronic
chr2:11412952(-) A-I      intronic
chr2:11329040(-) A-I      intronic
chr2:11328449(-) A-I      intronic
chr2:11328297(-) A-I      intronic
chr2:11328455(-) A-I      intronic
chr2:11360281(-) A-I      intronic
chr2:11360343(-) A-I      intronic
chr2:11419031(-) A-I      intronic
chr2:11410159(-) A-I      intronic
chr2:11412755(-) A-I      intronic
chr2:11328437(-) A-I      intronic
chr2:11419012(-) A-I      intronic
chr2:11478413(-) A-I      intronic
chr2:11328304(-) A-I      intronic
chr2:11442127(-) A-I      intronic
chr2:11329079(-) A-I      intronic
chr2:11321776(-) A-I      3'UTR
chr2:11325795(-) A-I      intronic
chr2:11425870(-) A-I      intronic
chr2:11423136(-) A-I      intronic
chr2:11442140(-) A-I      intronic
chr2:11330115(-) A-I      intronic
chr2:11360075(-) A-I      intronic
chr2:11360272(-) A-I      intronic
chr2:11461593(-) A-I      intronic
chr2:11360213(-) A-I      intronic
chr2:11425810(-) A-I      intronic
chr2:11442544(-) A-I      intronic
chr2:11387985(-) A-I      intronic
chr2:11412874(-) A-I      intronic
chr2:11410079(-) A-I      intronic
chr2:11388723(-) A-I      intronic
chr2:11388752(-) A-I      intronic
chr2:11467827(-) A-I      intronic
chr2:11442069(-) A-I      intronic
chr2:11389227(-) A-I      intronic
chr2:11477972(-) A-I      intronic
chr2:11415999(-) A-I      intronic
chr2:11325650(-) A-I      intronic
chr2:11329093(-) A-I      intronic
chr2:11418916(-) A-I      intronic
chr2:11345987(-) A-I      intronic
chr2:11412814(-) A-I      intronic
chr2:11373283(-) A-I      intronic
chr2:11352218(-) A-I      intronic
chr2:11388687(-) A-I      intronic
chr2:11329857(-) A-I      intronic
chr2:11478466(-) A-I      intronic
chr2:11442070(-) A-I      intronic
chr2:11442169(-) A-I      intronic
chr2:11359515(-) A-I      intronic
chr2:11329941(-) A-I      intronic
chr2:11435187(-) A-I      intronic
chr2:11325651(-) A-I      intronic
chr2:11477924(-) A-I      intronic
chr2:11418922(-) A-I      intronic
chr2:11425853(-) A-I      intronic
chr2:11388599(-) A-I      intronic
chr2:11329080(-) A-I      intronic
chr2:11346194(-) A-I      intronic
chr2:11435052(-) A-I      intronic
chr2:11352322(-) A-I      intronic
chr2:11477870(-) A-I      intronic
chr2:11384802(-) A-I      intronic
chr2:11425791(-) A-I      intronic
chr2:11425770(-) A-I      intronic
chr2:11477247(-) A-I      intronic
chr2:11442572(-) A-I      intronic
chr2:11329086(-) A-I      intronic
chr2:11330082(-) A-I      intronic
chr2:11372486(-) A-I      intronic
chr2:11325874(-) A-I      intronic
chr2:11360362(-) A-I      intronic
chr2:11476620(-) A-I      intronic
chr2:11477892(-) A-I      intronic
chr2:11425349(-) A-I      intronic
chr2:11342903(-) A-I      intronic
chr2:11389197(-) A-I      intronic
chr2:11412788(-) A-I      intronic
chr2:11410015(-) A-I      intronic
chr2:11329149(-) A-I      intronic
chr2:11478267(-) A-I      intronic
chr2:11360249(-) A-I      intronic
chr2:11328279(-) A-I      intronic
chr2:11415217(-) A-I      intronic
chr2:11328888(-) A-I      intronic
chr2:11434028(-) A-I      intronic
chr2:11330018(-) A-I      intronic
chr2:11329137(-) A-I      intronic
chr2:11435068(-) A-I      intronic
chr2:11329062(-) A-I      intronic
chr2:11388713(-) A-I      intronic
chr2:11442562(-) A-I      intronic
chr2:11415261(-) A-I      intronic
chr2:11467888(-) A-I      intronic
chr2:11425694(-) A-I      intronic
chr2:11425877(-) A-I      intronic
chr2:11389176(-) A-I      intronic
chr2:11447708(-) A-I      intronic
chr2:11388065(-) A-I      intronic
chr2:11409580(-) A-I      intronic
chr2:11384800(-) A-I      intronic
chr2:11335916(-) A-I      intronic
chr2:11477249(-) A-I      intronic
Resource Symbol Editing Position Change SeqReg exReg PMID
DARNED ROCK2
chr2:11323239(-) A-I exon 3'UTR    19478186
chr2:11397668(-) A-I intron -    22327324
chr2:11328279(-) A-I intron -    22028664
chr2:11328297(-) A-I intron -    22028664
chr2:11328304(-) A-I intron -    22028664
chr2:11328309(-) A-I intron -    22028664
chr2:11328310(-) A-I intron -    22028664
chr2:11328373(-) A-I intron -    22028664
chr2:11328374(-) A-I intron -    22028664
chr2:11328400(-) A-I intron -    22028664
chr2:11328429(-) A-I intron -    22028664
chr2:11328437(-) A-I intron -    22028664
chr2:11328449(-) A-I intron -    22028664
chr2:11328455(-) A-I intron -    22028664
chr2:11328482(-) A-I intron -    22028664
chr2:11328487(-) A-I intron -    22028664
chr2:11328509(-) A-I intron -    22028664
chr2:11328515(-) A-I intron -    22028664
chr2:11329086(-) A-G intron -    22484847
chr2:11329137(-) A-G intron -    22484847
chr2:11329925(-) A-G intron -    22484847
chr2:11329991(-) A-G intron -    22484847
chr2:11329995(-) A-G intron -    22484847
chr2:11330071(-) A-G intron -    22484847
chr2:11330107(-) A-G intron -    22484847
chr2:11330115(-) A-G intron -    22484847
chr2:11359389(-) A-G intron -    22484847
chr2:11389159(-) A-G intron -    22484847
chr2:11389176(-) A-G intron -    22484847
chr2:11389186(-) A-G intron -    22484847
chr2:11389197(-) A-G intron -    22484847
chr2:11389227(-) A-G intron -    22484847
chr2:11412755(-) A-G intron -    22484847
chr2:11412788(-) A-G intron -    22484847
chr2:11415217(-) A-G intron -    22484847
chr2:11415261(-) A-G intron -    22484847
chr2:11418963(-) A-G intron -    22484847
chr2:11418967(-) A-G intron -    22484847
chr2:11425266(-) A-G intron -    22484847
chr2:11425349(-) A-G intron -    22484847
chr2:11442069(-) A-G intron -    22484847
chr2:11442070(-) A-G intron -    22484847
chr2:11442127(-) A-G intron -    22484847
chr2:11442140(-) A-G intron -    22484847
chr2:11442544(-) A-G intron -    22484847
chr2:11442562(-) A-G intron -    22484847
chr2:11447708(-) A-G intron -    22484847
chr2:11477247(-) A-G intron -    22484847
chr2:11477924(-) A-G intron -    22484847
chr2:11478267(-) A-G intron -    22484847

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase ROCK2
chr2:11319898-11319899(-) m6A 3'UTR       27773535
chr2:11320056-11320057(-) m6A 3'UTR       24284625//27773535
chr2:11320163-11320164(-) m6A 3'UTR       24284625
chr2:11320185-11320186(-) m6A 3'UTR       24284625
chr2:11320315-11320316(-) m6A 3'UTR       24284625//24981863//22575960//22608085
chr2:11320337-11320338(-) m6A 3'UTR       24284625//24981863//22575960//22608085
chr2:11320343-11320344(-) m6A 3'UTR       24284625//24981863//22575960//22608085
chr2:11320434-11320435(-) m6A 3'UTR       24284625//24981863
chr2:11321297-11321298(-) m6A 3'UTR       27773535
chr2:11323047-11323048(-) m6A 3'UTR       26404942//27773535
chr2:11323106-11323107(-) m6A 3'UTR       24284625//24981863//26404942//27773535//22608085
chr2:11323236-11323237(-) m6A 3'UTR       24284625//24209618//25456834//24981863//26404942//27773535//27371828//22575960//22608085
chr2:11323315-11323316(-) m6A 3'UTR       24284625//24209618//24981863//26404942//27773535//27371828//22575960//22608085
chr2:11323341-11323342(-) m6A 3'UTR       24284625//24209618//24981863//26404942//27773535//22575960//22608085
chr2:11323363-11323364(-) m6A 3'UTR       24284625//24209618//24981863//26404942//27773535//22575960//22608085
chr2:11323451-11323452(-) m6A 3'UTR       24284625//24209618//24981863//26404942//27773535//22575960//22608085
chr2:11323502-11323503(-) m6A 3'UTR       24284625//24209618//24981863//26404942//27773535//22575960//22608085
chr2:11323507-11323508(-) m6A 3'UTR       24284625//24209618//24981863//26404942//27773535//22575960//22608085
chr2:11332278-11332279(-) m6A CDS       24284625//24209618//24981863//27773535//22575960
chr2:11332282-11332283(-) m6A CDS       24284625//24209618//24981863//26404942//27773535//22608085
chr2:11332321-11332322(-) m6A CDS       24284625//24209618//24981863//26404942//27773535//22608085
chr2:11332343-11332344(-) m6A CDS       24284625//24209618//26404942//27773535
chr2:11332369-11332370(-) m6A CDS       24284625//27773535
chr2:11332745-11332746(-) m6A CDS       26404942
chr2:11332802-11332803(-) m6A CDS//exon       24981863//26404942//27773535
chr2:11333951-11333952(-) m6A CDS//exon       24981863//27773535//22575960
chr2:11334413-11334414(-) m6A CDS//exon       26404942
chr2:11334425-11334426(-) m6A CDS//exon       26404942
chr2:11335111-11335112(-) m6A CDS//exon       26404942
chr2:11337415-11337416(-) m6A CDS       24981863//26404942//27773535
chr2:11337424-11337425(-) m6A CDS       24981863//26404942//27773535//22575960
chr2:11337441-11337442(-) m6A CDS       24981863//26404942//27773535//22575960
chr2:11337669-11337670(-) m6A CDS       24981863//26404942//27773535//22575960
chr2:11337792-11337793(-) m6A CDS       24981863//27773535//22575960
chr2:11338621-11338622(-) m6A CDS       24981863//27773535//22575960
chr2:11338630-11338631(-) m6A CDS       24981863//27773535//22575960
chr2:11338881-11338882(-) m6A CDS       24981863//27773535//22575960
chr2:11338890-11338891(-) m6A CDS       24981863//27773535//22575960
chr2:11341112-11341113(-) m6A CDS       24981863//27773535//22575960
chr2:11341118-11341119(-) m6A CDS       24981863//27773535//22575960
chr2:11341124-11341125(-) m6A CDS       24981863//27773535//22575960
chr2:11341165-11341166(-) Am CDS       -
chr2:11341190-11341191(-) m6A CDS       24981863//27773535
chr2:11341266-11341267(-) m6A CDS       24981863//27773535
chr2:11341455-11341456(-) m6A CDS       24981863//27773535
chr2:11341482-11341483(-) m6A CDS       24981863//27773535//22575960
chr2:11341487-11341488(-) m6A CDS       24981863//27773535//22575960
chr2:11341526-11341527(-) m6A CDS       24981863//27773535//22575960
chr2:11342189-11342190(-) m6A CDS       24981863//27773535//22575960
chr2:11347859-11347860(-) m6A CDS       24981863//27773535//22575960
chr2:11347871-11347872(-) m6A CDS       24981863//27773535//22575960
chr2:11347881-11347882(-) m6A CDS       24981863//27773535//22575960
chr2:11347960-11347961(-) m6A CDS       24981863//27773535//22608085
chr2:11348002-11348003(-) m6A CDS       24981863//27773535//22608085
chr2:11348028-11348029(-) m6A CDS       24284625//24981863//27773535//22608085
chr2:11348436-11348437(-) m6A CDS       24284625//24981863//27773535//22608085
chr2:11348469-11348470(-) m6A CDS       24284625//24981863//27773535//22608085
chr2:11348482-11348483(-) m6A CDS       24284625//24981863//27773535//22608085
chr2:11348521-11348522(-) m6A CDS       24284625//24981863//27773535//22608085
chr2:11348535-11348536(-) m6A CDS       24284625//24981863//27773535//22608085
chr2:11348543-11348544(-) m6A CDS       24284625//24981863//27773535//22608085
chr2:11351888-11351889(-) m6A CDS       24284625//24981863//27773535//22575960//22608085
chr2:11351903-11351904(-) m6A CDS       24284625//24981863//27773535//22575960//22608085
chr2:11354515-11354516(-) m6A 5'UTR//CDS       24981863//27773535//22575960//22608085
chr2:11354527-11354528(-) m6A 5'UTR//CDS       24981863//27773535//22575960//22608085
chr2:11354998-11354999(-) m6A 5'UTR//CDS       24981863//27773535
chr2:11355056-11355057(-) m6A 5'UTR//CDS       24981863//27773535
chr2:11355070-11355071(-) m6A 5'UTR//CDS       24981863//27773535
chr2:11355084-11355085(-) m6A 5'UTR//CDS       24981863//27773535
chr2:11355131-11355132(-) m6A 5'UTR//CDS       24981863
chr2:11355151-11355152(-) m6A 5'UTR//CDS       24981863
chr2:11355184-11355185(-) m6A 5'UTR//CDS       24981863
chr2:11355202-11355203(-) m6A 5'UTR//CDS       24981863
chr2:11355449-11355450(-) m6A 5'UTR//CDS       24981863
chr2:11355489-11355490(-) m6A 3'UTR//5'UTR//CDS       24981863
chr2:11355661-11355662(-) m6A 3'UTR//5'UTR//CDS       24981863
chr2:11355735-11355736(-) m6A 3'UTR//5'UTR//CDS       24981863//22575960
chr2:11356306-11356307(-) m6A 3'UTR//5'UTR//CDS       24981863//22575960
chr2:11357226-11357227(-) m6A 3'UTR//5'UTR//CDS       24981863//22575960
chr2:11357232-11357233(-) m6A 3'UTR//5'UTR//CDS       24981863//22575960
chr2:11357265-11357266(-) m6A 3'UTR//5'UTR//CDS       24981863//22575960
chr2:11357283-11357284(-) m6A 3'UTR//5'UTR//CDS       24981863//22575960
chr2:11367490-11367491(-) m6A 5'UTR//CDS       22575960
chr2:11484155-11484156(-) m6A 5'UTR//CDS//intron       27773536
chr2:11484216-11484217(-) m6A 5'UTR//CDS//intron       24209618//27371828//27773536
chr2:11484304-11484305(-) m6A 5'UTR//intron       24284625//24209618//27371828//27773536//22575960
chr2:11484399-11484400(-) m6A 5'UTR//intron       24284625//24209618//27371828//27773536//22575960
chr2:11484411-11484412(-) m6A 5'UTR//intron       24284625//24209618//27371828//27773536//22575960
chr2:11484536-11484537(-) m6A 5'UTR//intron       24209618//24981863//27371828//27773536//22575960//22608085
chr2:11484544-11484545(-) m6A 5'UTR//intron       24209618//24981863//27371828//27773536//22575960//22608085
chr2:11484567-11484568(-) m6A 5'UTR//intron       24209618//24981863//27371828//27773536//22575960//22608085
chr2:11488322-11488323(-) m6A exon       24209618//24981863//27371828//27773536//22575960
chr2:11488340-11488341(-) m6A exon       24209618//24981863//22575960

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-138-5p
Exosome Brain tissue     23382797
Exosome Plasma     23663360
Exosome Blood|Endothelial cells     -
Microvesicle Cerebrospinal fluid     24797360
Microvesicle Blood|Fibroblasts|Mesenchymal stem cells|Urine     -
Mitochondrion Skeletal muscle myoblasts     21637849
Mitochondrion Cell line (HEK-293|HeLa)     22984580
ROCK2
Chromatin HCC cell line (HepG2)|K562 cells     -
Cytosol Human myelogenous leukemia cell line (K-562)     21613539
Cytosol HCC cell line (HepG2)|K562 cells     -
Exosome Blood     -
Insoluble cytoplasm HCC cell line (HepG2)     -
Membrane HCC cell line (HepG2)|K562 cells     -
Nucleoplasm K562 cells     -
Nucleus Colon cancer cells     24393600
Nucleus HCC cell line (HepG2)|HeLa-S3 cells|K562 cells     -
Ribosome HEK-293 cells     22199352

Related Drug Information:


Resource Symbol Drug Name PubChem
ID		 Function
ncDR hsa-miR-138-5p
Fludarabine 657237 Drug sensitive
Pyrazolo[1,5-b]pyridazine deriv. 22 6539364 Drug resistant
Psammaplin A 6400741 Drug sensitive
Melampodin B acetate 5359212 Drug resistant
4-Cycloheptyl-N-(1-pyridin-2-ylethylideneamino)piperazine-1-carbothioamide 5351332 Drug resistant
Reumycin 5351216 Drug sensitive
Streptonigrin 5298 Drug sensitive
Ayanin 5280682 Drug sensitive
10-Hydroxy-1,2,6a,6b,9,9,12a-heptamethyl-2,3,4,5,6,6a,7,8,8a,10,11,12-dodecahydro-1H-picene-4a-carboxylic acid 495604 Drug sensitive
Formycin A 447199 Drug sensitive
Triacetyl crambescidin 800 hydrochloride 400721 Drug resistant
Massoia lactone 39914 Drug resistant
2-(2-(Dimethylamino)ethylamino)naphthazarin 376950 Drug resistant
5,8-Dihydroxy-2-[4-[2-(2-hydroxyethoxy)ethyl]piperazin-1-yl]naphthalene-1,4-dione 376948 Drug resistant
Antineoplastic-642316 369949 Drug resistant
6-(Dimethylarsanylsulfanylmethyl)oxane-2,3,4,5-tetrol 311912 Drug resistant
N-[1-(Biphenyl-4-yl)ethyl]-3,4-dichlorobenzamide 305114 Drug sensitive
2,4,6-Trichloro-5-ethylpyrimidine 249455 Drug resistant
N-(3-(1-Aziridinyl)propyl)-1,4-butanediamine 160394 Drug sensitive
[(1R,2R,4R,6E,9R,10S)-2,7-Dimethyl-5,8,14-trioxo-10-prop-1-en-2-yl-15-oxatricyclo[11.2.1.02,4]hexadeca-6,13(16)-dien-9-yl] acetate 15384977 Drug resistant
4-[[(1-Benzylpyrazolo[3,4-d]pyrimidin-4-yl)hydrazinylidene]methyl]-2-methoxyphenol 136091540 Drug sensitive
2,4-Dihydroxybenzaldehyde 2-pyridylhydrazone 135509512 Drug sensitive
DTIC-Dome 135398738 Drug sensitive
Litmomycin 12310334 Drug resistant
Binimetinib 10288191 Drug resistant
(3Z,4R)-4-Hydroxy-3-[2-[(1S,3R)-3-[2-[(1S,3S,3'R,4S)-1-hydroxy-4,6,6-trimethylspiro[2,5-dioxabicyclo[2.2.2]octane-3,6'-oxane]-3'-yl]ethyl]-2,2-dimethyl-6-methylidenecyclohexyl]ethylidene]oxolan-2-one 101206903 Drug resistant
12h-benzoxazolo[2,3-b]quinazolin-12-one, 3-nitro- - Drug resistant
2,4-pentanedionato(1,5-cyclooctadiene)rhodium - Drug resistant
21h,23h-porphine, pyridinium deriv., silver complex - Drug resistant
4-morpholinecarbodithioic acid, antimony complex - Drug resistant
7-n,n-dimethylamino brefeldin a hydrochloride - Drug resistant
benzo[b]naphtho[2,3-d]furan-6,11-dione, 4-chloro-3-hydroxy - Drug resistant
pyrimidine, 2,4,5-trichloro-6-isopropyl- - Drug resistant
2-(1-(4-chlorophenylsulfonyl)-1H-indol-3-yl)-2-oxo-N-(pyridin-4-yl)acetamide - Drug resistant
9-methoxy-5-hydroxycamptothecin - Drug resistant
antineoplastic-625543 - Drug resistant
b705009k098 - Drug resistant
bis(2-nitrophenyl)sulfilimine - Drug resistant
ERB-38 Immunotoxin - Drug resistant
(z) 4-acetoxy-(3,4',5)-trimethoxystilbene - Drug sensitive
1-naphthalenecarboxamide, n,n'-1,8-(octanediyl)bis- - Drug sensitive
3',4',5'-trimethoxy-3-hydroxy flavone - Drug sensitive
5.alpha.,25d-spirostan-3.beta.-ol glycoside - Drug sensitive
9h-quino[4,3,2-de][1,10]phenanthrolin-9-one, 10-methoxy- - Drug sensitive
breast chalone, glycoprotein fraction - Drug sensitive
phosphinic acid, bis(1-aziridinyl)-, 2-naphthyl ester - Drug sensitive
(-)-furodysinin - Drug sensitive
CI-921: amsacrine derivative - Drug sensitive
crotoxin cd - Drug sensitive
insulin-methotrexate conjugate - Drug sensitive
protein toxin c 10 - mw approx. 6700 - Drug sensitive
staurosporin analog kt 5944 - Drug sensitive
Resource Symbol Drug Name PubChem
ID		 Function Link  
RNAInter hsa-miR-138-5p
Gemcitabine 60750 Drug interaction    RC00002766
Vincristine 5978 Drug interaction    RC00002763
D-Glucose 5793 Drug interaction    RC00002762
Diethylstilbestrol 448537 Drug interaction    RC00002771
Cyclopamine 442972 Drug interaction    RC00002770
Paclitaxel 36314 Drug interaction    RC00002765
5-Fluorouracil 3385 Drug interaction    RC00002761
Doxorubicin 31703 Drug interaction    RC00002764
cis-Diaminedichloroplatinum 2767 Drug interaction    RC00002760
Docetaxel 148124 Drug interaction    RC00002769
Gefitinib 123631 Drug interaction    RC00002768
Ginsenoside Rh2 119307 Drug interaction    RC00002767
Y15 - Drug interaction    RC00002773
FAK inhibitor - Drug interaction    RC00002772
Resource Symbol Drug Name PubChem ID PMID
NoncoRNA hsa-miR-138-5p
Cisplatin 5702198       30535472
Gefitinib 123631       24582749

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-138-5p
Interactor2: ROCK2

Evidence Support:


Weak-Evidence MiRNA microarray
Prediction-Evidence microRNA.org//PITA//Targetscan
Support Database ViRBase

References:


PMID 29059211 Target region 3'UTR
Source ViRBase Interactor1 expression None
Tissue or cell line HUVECs Interactor2 expression None
Description The differential miRNAs and their target genes in the above pathways were concluded in Table S1 and Table S2.

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