Detail Information

Basic Information:


  VIRBase ID:  

HHID00091949

  Virus:  

Influenza A virus (A/California/07/2009(H1N1))

  Host:  

Homo sapiens

  Confidence Score:  

0.9124

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-30a-3p:           SCARB2:      

      *It may take a few minutes to display results.

Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-30a-3p SCARB2
miRBase
Accession/Entrez ID		 MIMAT0000088 950
Organism Homo sapiens Homo sapiens
Category miRNA mRNA
Alias - AMRF//CD36L2//EPM4//HLGP85//LGP85//LIMP-2//LIMPII//SR-BII

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-30a-3p
rs149150037 chr6:71403567    G/A
rs149150037 chr6:71403567    G/C
rs370184894 chr6:71403566    C/A
rs370184894 chr6:71403566    C/T
rs552541514 chr6:71403558    C/G
rs745605208 chr6:71403563    ATCCG/A
rs746505574 chr6:71403557    G/A
rs746505574 chr6:71403557    G/T
rs746965145 chr6:71403554    GCT/G
rs750918072 chr6:71403564    T/C
rs765735953 chr6:71403560    A/T
rs770865356 chr6:71403559    A/AC
rs776574456 chr6:71403560    A/AAGCTGGAGT
rs368070339 chr6:71403571    G/A
rs769702885 chr6:71403570    TG/T
rs775921090 chr6:71403574    AGCC/A
rs781617967 chr6:71403573    A/T

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR SCARB2
chr4:77111405(-) A-I      intronic
chr4:77113040(-) A-I      intronic
chr4:77113062(-) A-I      intronic
chr4:77113068(-) A-I      intronic
chr4:77113080(-) A-I      intronic
chr4:77113103(-) A-I      intronic
chr4:77111362(-) A-I      intronic
chr4:77113905(-) A-I      intronic
chr4:77113961(-) A-I      intronic
chr4:77113972(-) A-I      intronic
chr4:77104068(-) A-I      intronic
chr4:77104052(-) A-I      intronic
chr4:77104044(-) A-I      intronic
chr4:77111381(-) A-I      intronic
chr4:77104043(-) A-I      intronic
chr4:77111359(-) A-I      intronic
chr4:77111358(-) A-I      intronic
chr4:77105878(-) A-I      intronic
chr4:77105867(-) A-I      intronic
chr4:77105866(-) A-I      intronic
chr4:77113948(-) A-I      intronic
chr4:77113923(-) A-I      intronic
chr4:77113175(-) A-I      intronic
chr4:77111861(-) A-I      intronic
chr4:77105901(-) A-I      intronic
chr4:77105872(-) A-I      intronic
chr4:77104038(-) A-I      intronic
chr4:77110867(-) A-I      intronic
chr4:77115394(-) A-I      intronic
chr4:77080712(-) A-I      3'UTR
chr4:77080695(-) A-I      3'UTR
chr4:77080692(-) A-I      3'UTR
chr4:77080683(-) A-I      3'UTR
chr4:77080642(-) A-I      3'UTR
chr4:77100433(-) A-I      intronic
chr4:77110871(-) A-I      intronic
chr4:77113197(-) A-I      intronic
chr4:77111290(-) A-I      intronic
chr4:77110752(-) A-I      intronic
chr4:77105852(-) A-I      intronic
chr4:77080860(-) A-I      3'UTR
chr4:77110732(-) A-I      intronic
chr4:77110683(-) A-I      intronic
chr4:77113191(-) A-I      intronic
chr4:77111344(-) A-I      intronic
chr4:77113196(-) A-I      intronic
chr4:77102991(-) A-I      intronic
chr4:77111438(-) A-I      intronic
chr4:77105853(-) A-I      intronic
chr4:77111395(-) A-I      intronic
chr4:77111435(-) A-I      intronic
chr4:77116511(-) A-I      intronic
chr4:77102975(-) A-I      intronic
chr4:77105928(-) A-I      intronic
chr4:77113093(-) A-I      intronic
chr4:77105927(-) A-I      intronic
chr4:77110880(-) A-I      intronic
chr4:77124260(-) A-I      intronic
chr4:77102790(-) A-I      intronic
Resource Symbol Editing Position Change SeqReg exReg PMID
DARNED SCARB2
chr4:77080771(-) A-T exon 3'UTR    21725310
chr4:77115309(-) A-G intron -    22484847
chr4:77102991(-) A-G intron -    22484847
chr4:77103005(-) A-G intron -    22484847
chr4:77110823(-) A-G intron -    22484847
chr4:77111837(-) A-G intron -    22484847
chr4:77113889(-) A-G intron -    22484847
chr4:77113974(-) A-G intron -    22484847
chr4:77116511(-) A-G intron -    22484847

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase SCARB2
chr4:77082728-77082729(-) m6A 3'UTR       24981863
chr4:77082752-77082753(-) m6A 3'UTR       24981863
chr4:77082800-77082801(-) m6A 3'UTR       24981863//27371828
chr4:77082840-77082841(-) m6A 3'UTR       27371828
chr4:77134591-77134592(-) Gm CDS       -
chr4:77134828-77134829(-) m6A 5'UTR       27773536
chr4:77134921-77134922(-) m6A 5'UTR       24981863//27773536
chr4:77134927-77134928(-) m6A 5'UTR       24981863//27773536

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-30a-3p
Exosome Brain tissue     23382797
Exosome Plasma     23663360
Exosome Breast milk|Endothelial cells|Epithelial cells|Tongue tissue     -
Microvesicle Seminal plasma     23539611
Microvesicle Follicular fluid     23666971
Microvesicle Serum     24797360
Microvesicle Fibroblasts|Mesenchymal stem cells|Urine     -
Mitochondrion Skeletal muscle myoblasts     21637849
Mitochondrion Cell line (HEK-293|HeLa)     22984580
SCARB2
Cytoplasm Nasopharyngeal carcinoma cells     20498841
Endoplasmic reticulum Human myelogenous leukemia cell line (K-562)     21613539
Exosome Blood     -
Nucleus Nasopharyngeal carcinoma cells     20498841
Ribosome HEK-293 cells     22199352
Ribosome Colon cancer cells     24393600

Related Drug Information:


Resource Symbol Drug Name PubChem
ID		 Function Link  
RNAInter hsa-miR-30a-3p
Sorafenib 216239 Drug interaction    RC00000903
Resource Symbol Drug Name PubChem ID PMID
NoncoRNA hsa-miR-30a-3p
Imatinib 5291       25349971

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-30a-3p
Interactor2: SCARB2

Evidence Support:


Strong-Evidence qRT-PCR
Weak-Evidence Deep sequencing//Microarray
Prediction-Evidence microRNA.org//PITA//Targetscan
Support Database ViRBase

References:


PMID 31207403 Target region None
Source ViRBase Interactor1 expression None
Tissue or cell line None Interactor2 expression None
Description Relationships between 4 miRNAs and 5 inversely correlated target genes selected in qRT-PCR.

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