The database microT-CDS (http://diana.imis.athena-innovation.gr/DianaTools/index.php r=microT_CDS/index), the positional relationships between miRNAs, and genomic annotation sets were used for the prediction of targets of the 130 DE miRNAs.To explore the regulatory roles of the DE miRNAs from this study, web prediction programs were used to predict their putative target genes (S3 Table).