Basic Information:

  VIRBase ID:  

HHID00076468

  Virus:  

Murid betaherpesvirus 1

  Host:  

Mus musculus

  Confidence Score:  

0.5711

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      mmu-miR-199a-3p:  MIMAT0000230          Ankrd13c:  NM_001359909     

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Interactor Information:

	Interactor1	Interactor2
Symbol	mmu-miR-199a-3p	Ankrd13c
miRBase Accession/Entrez ID	MIMAT0000230	433667
Organism	Mus musculus	Mus musculus
Category	miRNA	mRNA
Alias	-	AI505652//AU022220

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	Ankrd13c	chr3:157947394-157947395(+) m6A 5'UTR       25412662//24981863//25569111 chr3:157947560-157947561(+) m6A CDS//exon       25683224//25412662//24981863//25569111 chr3:157947657-157947658(+) m6A CDS//exon       25683224//25456834//25412662//24981863//25569111 chr3:157947906-157947907(+) m6A CDS//exon       25683224//25456834//24981863//25569111 chr3:157947939-157947940(+) m6A CDS//exon       25683224//25456834//24981863//25569111 chr3:157960986-157960987(+) m6A CDS//exon       25683224//24981863//25569111 chr3:157991782-157991783(+) m6A 3'UTR//CDS//exon       25412662//22608085 chr3:157991809-157991810(+) m6A 3'UTR//CDS//exon       25412662//22608085 chr3:157993704-157993705(+) m6A exon//intron       25683224//25412662//22608085 chr3:157994564-157994565(+) m6A exon//intron       25683224//25412662 chr3:157994609-157994610(+) m6A 3'UTR//CDS//exon       25683224//25412662 chr3:157994621-157994622(+) m6A 3'UTR//CDS//exon       25683224//25412662//24981863 chr3:157994640-157994641(+) m6A 3'UTR//CDS//exon       25683224//25412662//24981863 chr3:157994687-157994688(+) m6A 3'UTR//CDS//exon       25683224//25412662//24981863 chr3:157994699-157994700(+) m6A 3'UTR//CDS//exon       25683224//25412662//24981863 chr3:157998592-157998593(+) m6A exon//intron       24981863//22608085 chr3:157999667-157999668(+) m6A 3'UTR//CDS//exon       24981863 chr3:157999693-157999694(+) m6A 3'UTR//CDS//exon       24981863 chr3:158001094-158001095(+) m6A 3'UTR//CDS//exon       24981863//22608085 chr3:158001119-158001120(+) m6A 3'UTR//CDS//exon       24981863//22608085 chr3:158005832-158005833(+) m6A 3'UTR//CDS//exon       24981863//25569111 chr3:158005844-158005845(+) m6A 3'UTR//CDS//exon       24981863//25569111 chr3:158005955-158005956(+) m6A 3'UTR//exon       24981863//25456834//25569111 chr3:158005971-158005972(+) m6A 3'UTR//exon       24981863//25456834//25569111 chr3:158006057-158006058(+) m6A 3'UTR//exon       24981863//25456834//25569111

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	mmu-miR-199a-3p	Exosome Conditioned medium of E13 SMG     28041903 Exosome B6 BMDCs     22031862

Interaction Network (The top 100 interactions):

Interactor1: mmu-miR-199a-3p
Interactor2: Ankrd13c

Evidence Support:

Weak-Evidence	MiRNA microarray
Prediction-Evidence	Targetscan
Support Database	ViRBase

References:

PMID	20643939	Target region	None
Source	ViRBase	Interactor1 expression	Upregulation
Tissue or cell line	NIH3T3 cells	Interactor2 expression	Downregulation
Description	All of the regulated genes in Fig. 5B are down-regulated by miR-199a-3p mimic and up-regulated by miR-199a-3p inhibitor compared with the negative transfection control, with the exception of ITGA6, which is only up-regulated by the inhibitor (Dataset S3).