Basic Information:

  VIRBase ID:  

HHID00076460

  Virus:  

Murid betaherpesvirus 1

  Host:  

Mus musculus

  Confidence Score:  

0.5711

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      mmu-miR-199a-3p:  MIMAT0000230          Dusp5:  NM_001085390     

      *It may take a few minutes to display results.

Interactor Information:

	Interactor1	Interactor2
Symbol	mmu-miR-199a-3p	Dusp5
miRBase Accession/Entrez ID	MIMAT0000230	240672
Organism	Mus musculus	Mus musculus
Category	miRNA	mRNA
Alias	-	Gm337

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	Dusp5	chr19:53529585-53529586(+) m6A CDS       25412662//25569111 chr19:53533836-53533837(+) m6A CDS       25412662//25569111 chr19:53533958-53533959(+) m6A CDS       25412662//25569111//22608085 chr19:53537570-53537571(+) m6A CDS       25412662//24981863//25569111 chr19:53537622-53537623(+) m6A CDS       25412662//24981863//25569111 chr19:53541007-53541008(+) m6A CDS       25683224//25456834//25412662//24981863//25569111//22608085 chr19:53541090-53541091(+) m6A CDS       25683224//25456834//25412662//24981863//25569111//22608085 chr19:53541196-53541197(+) m6A CDS       25683224//25456834//25412662//24981863//25569111//22608085 chr19:53541323-53541324(+) m6A 3'UTR       25683224//25456834//25412662//24981863//25569111//22608085 chr19:53541395-53541396(+) m6A 3'UTR       25683224//25456834//25412662//24981863//25569111//22608085 chr19:53541403-53541404(+) m6A 3'UTR       25683224//25456834//25412662//24981863//25569111//22608085 chr19:53541430-53541431(+) m6A 3'UTR       25683224//25456834//25412662//24981863//25569111//22608085 chr19:53541492-53541493(+) m6A 3'UTR       25683224//25456834//25412662//24981863//25569111//22608085//22575960 chr19:53541518-53541519(+) m6A 3'UTR       25683224//25456834//25412662//24981863//25569111//22608085//22575960 chr19:53541579-53541580(+) m6A 3'UTR       25683224//25456834//25412662//24981863//25569111//22608085 chr19:53541596-53541597(+) m6A 3'UTR       25683224//25456834//25412662//24981863//25569111//22608085 chr19:53541692-53541693(+) m6A 3'UTR       25683224//25456834//25412662//24981863//25569111//22608085 chr19:53541751-53541752(+) m6A 3'UTR       25683224//25456834//25412662//24981863//25569111//22608085 chr19:53541761-53541762(+) m6A 3'UTR       25683224//25456834//25412662//24981863//25569111//22608085 chr19:53541794-53541795(+) m6A 3'UTR       25683224//25456834//25412662//24981863//25569111//22608085//22575960 chr19:53541842-53541843(+) m6A 3'UTR       25683224//25456834//25412662//24981863//25569111//22608085 chr19:53541865-53541866(+) m6A 3'UTR       25683224//25456834//25412662//24981863//25569111//22608085 chr19:53541906-53541907(+) m6A 3'UTR       25683224//25456834//25412662//24981863//25569111//22608085 chr19:53541978-53541979(+) m6A 3'UTR       25683224//25456834//25412662//24981863//25569111//22608085 chr19:53542067-53542068(+) m6A 3'UTR       24981863//25569111 chr19:53542074-53542075(+) m6A 3'UTR       24981863//25569111 chr19:53542219-53542220(+) m6A 3'UTR       25569111

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	mmu-miR-199a-3p	Exosome Conditioned medium of E13 SMG     28041903 Exosome B6 BMDCs     22031862

Interaction Network (The top 100 interactions):

Interactor1: mmu-miR-199a-3p
Interactor2: Dusp5

Evidence Support:

Weak-Evidence	MiRNA microarray
Prediction-Evidence	Targetscan
Support Database	ViRBase

References:

PMID	20643939	Target region	None
Source	ViRBase	Interactor1 expression	Upregulation
Tissue or cell line	NIH3T3 cells	Interactor2 expression	Downregulation
Description	All of the regulated genes in Fig. 5B are down-regulated by miR-199a-3p mimic and up-regulated by miR-199a-3p inhibitor compared with the negative transfection control, with the exception of ITGA6, which is only up-regulated by the inhibitor (Dataset S3).