Basic Information:

  VIRBase ID:  

HHID00076452

  Virus:  

Murid betaherpesvirus 1

  Host:  

Mus musculus

  Confidence Score:  

0.5711

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      mmu-miR-199a-3p:  MIMAT0000230          Ccnyl1:  NM_001097644     

      *It may take a few minutes to display results.

Interactor Information:

	Interactor1	Interactor2
Symbol	mmu-miR-199a-3p	Ccnyl1
miRBase Accession/Entrez ID	MIMAT0000230	227210
Organism	Mus musculus	Mus musculus
Category	miRNA	mRNA
Alias	-	9630037P07Rik//AW554339

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	Ccnyl1	chr1:64690516-64690517(+) m6A 5'UTR       25683224//24981863 chr1:64690537-64690538(+) m6A 5'UTR       25683224//24981863 chr1:64690577-64690578(+) m6A 5'UTR       25683224//24981863 chr1:64690605-64690606(+) m6A 5'UTR       25683224//24981863 chr1:64690632-64690633(+) m6A CDS       25683224//24981863 chr1:64690924-64690925(+) m6A 5'UTR//intron       25412662//24981863//25569111 chr1:64700986-64700987(+) m6A CDS       25412662 chr1:64708464-64708465(+) m6A CDS       24981863//22608085 chr1:64711449-64711450(+) m6A CDS       24981863//22608085 chr1:64713130-64713131(+) m6A CDS       24981863 chr1:64714609-64714610(+) m6A CDS       24981863 chr1:64718257-64718258(+) m6A CDS       24981863 chr1:64718278-64718279(+) m6A CDS       24981863 chr1:64718293-64718294(+) m6A CDS       - chr1:64721781-64721782(+) m6A CDS       25683224//25456834//24981863//25569111 chr1:64723544-64723545(+) m6A CDS       25683224//25456834//24981863//25569111//22608085 chr1:64723556-64723557(+) m6A CDS       25683224//25456834//24981863//25569111//22608085 chr1:64723646-64723647(+) m6A 3'UTR       25683224//25456834//25412662//24981863//25569111//22608085 chr1:64723661-64723662(+) m6A 3'UTR       25683224//25456834//25412662//24981863//25569111//22608085 chr1:64723670-64723671(+) m6A 3'UTR       25683224//25456834//25412662//24981863//25569111//22608085 chr1:64723681-64723682(+) m6A 3'UTR       25683224//25456834//25412662//24981863//25569111//22608085 chr1:64723731-64723732(+) m6A 3'UTR       25683224//25456834//25412662//24981863//25569111 chr1:64723749-64723750(+) m6A 3'UTR       25683224//25456834//25412662//24981863//25569111 chr1:64723765-64723766(+) m6A 3'UTR       25683224//25456834//25412662//24981863//25569111 chr1:64723772-64723773(+) m6A 3'UTR       25683224//25456834//25412662//24981863//25569111 chr1:64723805-64723806(+) m6A 3'UTR       25683224//25456834//24981863//25569111 chr1:64723857-64723858(+) m6A 3'UTR       25683224//25456834//24981863//25569111 chr1:64723954-64723955(+) m6A 3'UTR       25569111 chr1:64723967-64723968(+) m6A 3'UTR       25569111 chr1:64723999-64724000(+) m6A 3'UTR       25569111 chr1:64724028-64724029(+) m6A 3'UTR       - chr1:64724092-64724093(+) m6A 3'UTR       - chr1:64724898-64724899(+) m6A 3'UTR       25683224 chr1:64724901-64724902(+) Y 3'UTR//exon       26075521 chr1:64725140-64725141(+) m6A 3'UTR       25569111 chr1:64725165-64725166(+) m6A 3'UTR       25569111 chr1:64725251-64725252(+) m6A 3'UTR       25569111 chr1:64725451-64725452(+) m6A 3'UTR       25569111

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	mmu-miR-199a-3p	Exosome Conditioned medium of E13 SMG     28041903 Exosome B6 BMDCs     22031862
	Ccnyl1	Nucleus Neuroblastoma cell line (N2A)     22406755

Interaction Network (The top 100 interactions):

Interactor1: mmu-miR-199a-3p
Interactor2: Ccnyl1

Evidence Support:

Weak-Evidence	MiRNA microarray
Prediction-Evidence	Targetscan
Support Database	ViRBase

References:

PMID	20643939	Target region	None
Source	ViRBase	Interactor1 expression	Upregulation
Tissue or cell line	NIH3T3 cells	Interactor2 expression	Downregulation
Description	All of the regulated genes in Fig. 5B are down-regulated by miR-199a-3p mimic and up-regulated by miR-199a-3p inhibitor compared with the negative transfection control, with the exception of ITGA6, which is only up-regulated by the inhibitor (Dataset S3).