Basic Information:

  VIRBase ID:  

HHID00076450

  Virus:  

Murid betaherpesvirus 1

  Host:  

Mus musculus

  Confidence Score:  

0.5711

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      mmu-miR-199a-3p:  MIMAT0000230          D030056L22Rik:  NM_177640     

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Interactor Information:

	Interactor1	Interactor2
Symbol	mmu-miR-199a-3p	D030056L22Rik
miRBase Accession/Entrez ID	MIMAT0000230	225995
Organism	Mus musculus	Mus musculus
Category	miRNA	mRNA
Alias	-	-

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	D030056L22Rik	chr19:18713208-18713209(+) m6A 5'UTR       25412662//24981863//25456834//25569111 chr19:18713258-18713259(+) m6A 5'UTR       25683224//25412662//24981863//25456834//25569111 chr19:18713523-18713524(+) m6A CDS       25683224//25412662//24981863//25569111 chr19:18713583-18713584(+) m6A CDS       25683224//25412662//24981863//25569111 chr19:18717264-18717265(+) m6A CDS       25683224//25456834//25412662//24981863//25569111//22608085 chr19:18717312-18717313(+) m6A CDS       25683224//25456834//25412662//24981863//25569111//22608085 chr19:18717326-18717327(+) m6A CDS       25683224//25456834//25412662//24981863//25569111//22608085 chr19:18717336-18717337(+) m6A CDS       25683224//25456834//25412662//24981863//25569111//22608085 chr19:18717463-18717464(+) m6A 3'UTR       25683224//25456834//25412662//24981863//25569111//22608085 chr19:18717471-18717472(+) m6A 3'UTR       25683224//25456834//25412662//24981863//25569111//22608085 chr19:18717543-18717544(+) m6A 3'UTR       25683224//25456834//24981863//25569111//22608085 chr19:18717553-18717554(+) m6A 3'UTR       25683224//25456834//24981863//25569111//22608085

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	mmu-miR-199a-3p	Exosome Conditioned medium of E13 SMG     28041903 Exosome B6 BMDCs     22031862

Interaction Network (The top 100 interactions):

Interactor1: mmu-miR-199a-3p
Interactor2: D030056L22Rik

Evidence Support:

Weak-Evidence	MiRNA microarray
Prediction-Evidence	Targetscan
Support Database	ViRBase

References:

PMID	20643939	Target region	None
Source	ViRBase	Interactor1 expression	Upregulation
Tissue or cell line	NIH3T3 cells	Interactor2 expression	Downregulation
Description	All of the regulated genes in Fig. 5B are down-regulated by miR-199a-3p mimic and up-regulated by miR-199a-3p inhibitor compared with the negative transfection control, with the exception of ITGA6, which is only up-regulated by the inhibitor (Dataset S3).