Basic Information:

  VIRBase ID:  

HHID00076449

  Virus:  

Murid betaherpesvirus 1

  Host:  

Mus musculus

  Confidence Score:  

0.5711

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      mmu-miR-199a-3p:  MIMAT0000230          Etf1:  NM_144866     

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Interactor Information:

	Interactor1	Interactor2
Symbol	mmu-miR-199a-3p	Etf1
miRBase Accession/Entrez ID	MIMAT0000230	225363
Organism	Mus musculus	Mus musculus
Category	miRNA	mRNA
Alias	-	AI463371//D6Ertd109//D6Ertd109e//ERF//ERF1//SUP4//SUP45L1//TB3-1

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	Etf1	chr18:34903627-34903628(-) m6A 3'UTR       24981863//22608085 chr18:34903637-34903638(-) m6A 3'UTR       24981863//22608085 chr18:34903651-34903652(-) m6A 3'UTR       24981863//22608085 chr18:34903687-34903688(-) m6A 3'UTR       24981863 chr18:34903735-34903736(-) m6A 3'UTR       24981863 chr18:34903839-34903840(-) m6A 3'UTR       25569111 chr18:34903946-34903947(-) m6A 3'UTR       25412662 chr18:34903978-34903979(-) m6A 3'UTR       25412662 chr18:34904347-34904348(-) m6A 3'UTR       24981863//25569111 chr18:34904387-34904388(-) m6A 3'UTR       24981863//25569111 chr18:34904478-34904479(-) m6A 3'UTR       24981863//25569111 chr18:34904512-34904513(-) m6A 3'UTR       24981863//25569111 chr18:34904626-34904627(-) m6A 3'UTR       24981863//25569111 chr18:34904751-34904752(-) m6A 3'UTR       25683224//25456834//24981863//25569111//26404942//22608085 chr18:34904825-34904826(-) m6A 3'UTR       25683224//25456834//24981863//25569111//26404942//22608085//22575960 chr18:34904830-34904831(-) m6A 3'UTR       25683224//25456834//24981863//25569111//26404942//22608085//22575960 chr18:34904835-34904836(-) m6A 3'UTR       25683224//25456834//24981863//25569111//26404942//22608085//22575960 chr18:34904875-34904876(-) m6A 3'UTR       25683224//25456834//24981863//25569111//26404942//22608085//22575960 chr18:34906111-34906112(-) m6A CDS       25412662//22608085 chr18:34906117-34906118(-) m6A CDS       25412662//22608085 chr18:34906123-34906124(-) m6A CDS       25412662//22608085 chr18:34907621-34907622(-) m6A CDS       25412662//22608085 chr18:34907650-34907651(-) m6A CDS       25412662//22608085 chr18:34908169-34908170(-) m6A CDS       24981863//22608085 chr18:34914012-34914013(-) m6A CDS       25569111//22608085 chr18:34914018-34914019(-) m6A CDS       25569111//22608085 chr18:34914054-34914055(-) Y CDS//exon       26075521 chr18:34914061-34914062(-) m6A CDS       25569111//22608085 chr18:34914089-34914090(-) m6A CDS       25569111//22608085 chr18:34914133-34914134(-) m6A CDS       24981863//25569111//22608085 chr18:34931845-34931846(-) m6A 5'UTR//CDS       25412662//24981863//25456834//25569111

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	mmu-miR-199a-3p	Exosome Conditioned medium of E13 SMG     28041903 Exosome B6 BMDCs     22031862
	Etf1	Nucleus Neuroblastoma cell line (N2A)     22406755

Interaction Network (The top 100 interactions):

Interactor1: mmu-miR-199a-3p
Interactor2: Etf1

Evidence Support:

Weak-Evidence	MiRNA microarray
Prediction-Evidence	Targetscan
Support Database	ViRBase

References:

PMID	20643939	Target region	None
Source	ViRBase	Interactor1 expression	Upregulation
Tissue or cell line	NIH3T3 cells	Interactor2 expression	Downregulation
Description	All of the regulated genes in Fig. 5B are down-regulated by miR-199a-3p mimic and up-regulated by miR-199a-3p inhibitor compared with the negative transfection control, with the exception of ITGA6, which is only up-regulated by the inhibitor (Dataset S3).