Basic Information:

  VIRBase ID:  

HHID00076448

  Virus:  

Murid betaherpesvirus 1

  Host:  

Mus musculus

  Confidence Score:  

0.5711

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      mmu-miR-199a-3p:  MIMAT0000230          Lclat1:  NM_001081071     

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Interactor Information:

	Interactor1	Interactor2
Symbol	mmu-miR-199a-3p	Lclat1
miRBase Accession/Entrez ID	MIMAT0000230	225010
Organism	Mus musculus	Mus musculus
Category	miRNA	mRNA
Alias	-	1-AGPAT 8//AGP//Agpat8//AI181996//ALC//Alcat1//Gm91//Lyc//Lycat

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	Lclat1	chr17:73204256-73204257(+) m6A exon//intron       25569111 chr17:73204266-73204267(+) m6A exon//intron       25569111 chr17:73239723-73239724(+) m6A CDS//exon       24981863//25569111 chr17:73239776-73239777(+) m6A CDS//exon       24981863//25569111 chr17:73239801-73239802(+) m6A CDS//exon       25412662//24981863//25569111 chr17:73239870-73239871(+) m6A CDS//exon       25456834//25412662//24981863//25569111//22608085 chr17:73239945-73239946(+) m6A CDS//exon       25456834//25412662//24981863//25569111//22608085 chr17:73240144-73240145(+) m6A CDS//exon       25683224//25456834//24981863//25569111//22608085//22575960 chr17:73240159-73240160(+) m6A CDS//exon       25683224//25456834//24981863//25569111//22608085//22575960 chr17:73240241-73240242(+) m6A 3'UTR//exon       24981863//25456834//25569111 chr17:73240276-73240277(+) m6A 3'UTR//exon       24981863//25569111 chr17:73240465-73240466(+) m6A 3'UTR       24981863//25569111 chr17:73240485-73240486(+) m6A 3'UTR       24981863//25569111 chr17:73240510-73240511(+) m6A 3'UTR       24981863//25569111 chr17:73240529-73240530(+) m6A 3'UTR       24981863//25569111 chr17:73240562-73240563(+) m6A 3'UTR       24981863//25569111 chr17:73240612-73240613(+) m6A 3'UTR       24981863//25569111 chr17:73241980-73241981(+) m6A 3'UTR       24981863 chr17:73242596-73242597(+) m6A 3'UTR       24981863 chr17:73242614-73242615(+) m6A 3'UTR       24981863 chr17:73242646-73242647(+) m6A 3'UTR       24981863 chr17:73242682-73242683(+) m6A 3'UTR       24981863

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	mmu-miR-199a-3p	Exosome Conditioned medium of E13 SMG     28041903 Exosome B6 BMDCs     22031862

Interaction Network (The top 100 interactions):

Interactor1: mmu-miR-199a-3p
Interactor2: Lclat1

Evidence Support:

Weak-Evidence	MiRNA microarray
Prediction-Evidence	Targetscan
Support Database	ViRBase

References:

PMID	20643939	Target region	None
Source	ViRBase	Interactor1 expression	Upregulation
Tissue or cell line	NIH3T3 cells	Interactor2 expression	Downregulation
Description	All of the regulated genes in Fig. 5B are down-regulated by miR-199a-3p mimic and up-regulated by miR-199a-3p inhibitor compared with the negative transfection control, with the exception of ITGA6, which is only up-regulated by the inhibitor (Dataset S3).