Basic Information:

  VIRBase ID:  

HHID00076445

  Virus:  

Murid betaherpesvirus 1

  Host:  

Mus musculus

  Confidence Score:  

0.5711

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      mmu-miR-199a-3p:  MIMAT0000230          Trib2:  NM_144551     

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Interactor Information:

	Interactor1	Interactor2
Symbol	mmu-miR-199a-3p	Trib2
miRBase Accession/Entrez ID	MIMAT0000230	217410
Organism	Mus musculus	Mus musculus
Category	miRNA	mRNA
Alias	-	AW319517//TRB//TRB-2//TRB2

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	Trib2	chr12:15791814-15791815(-) m6A 3'UTR       25683224//24981863//22608085 chr12:15791829-15791830(-) m6A 3'UTR       25683224//24981863//22608085 chr12:15791887-15791888(-) m6A 3'UTR       25683224//24981863//25569111//26404942//22608085 chr12:15791984-15791985(-) m6A 3'UTR       25683224//24981863//25569111//22608085 chr12:15792010-15792011(-) m6A 3'UTR       25683224//25456834//24981863//25569111//22608085 chr12:15792060-15792061(-) m6A 3'UTR       25683224//25456834//24981863//25569111//22608085 chr12:15792123-15792124(-) m6A 3'UTR       25683224//24981863//25569111//22608085 chr12:15792229-15792230(-) m6A 3'UTR       25683224//24981863 chr12:15792640-15792641(-) m6A 3'UTR       25683224//22608085 chr12:15792654-15792655(-) m6A 3'UTR       25683224//22608085 chr12:15792766-15792767(-) m6A 3'UTR       25683224//22608085 chr12:15792873-15792874(-) m6A 3'UTR       25683224//24981863 chr12:15792888-15792889(-) m6A 3'UTR       25683224//24981863 chr12:15793065-15793066(-) m6A 3'UTR       25683224//24981863//26404942 chr12:15793076-15793077(-) m6A 3'UTR       25683224//24981863//26404942 chr12:15793089-15793090(-) m6A 3'UTR       25683224//24981863//26404942 chr12:15793100-15793101(-) m6A 3'UTR       25683224//24981863//26404942 chr12:15793168-15793169(-) m6A 3'UTR       25683224//24981863//26404942 chr12:15793202-15793203(-) m6A 3'UTR       25683224//24981863//26404942 chr12:15793261-15793262(-) m6A 3'UTR       25683224//24981863 chr12:15793276-15793277(-) m6A 3'UTR       25683224//24981863 chr12:15793435-15793436(-) m6A 3'UTR       25683224//25456834//24981863//25569111//22608085 chr12:15793450-15793451(-) m6A 3'UTR       25683224//25456834//24981863//25569111//26404942//22608085 chr12:15793509-15793510(-) m6A 3'UTR       25683224//25456834//25412662//24981863//25569111//26404942//22608085//22575960 chr12:15793540-15793541(-) m6A 3'UTR       25683224//25456834//25412662//24981863//25569111//26404942//22608085//22575960 chr12:15793591-15793592(-) m6A 3'UTR       25683224//25456834//25412662//24981863//25569111//26404942//22608085//22575960 chr12:15793623-15793624(-) m6A CDS       25683224//25456834//25412662//24981863//25569111//26404942//22608085//22575960 chr12:15793629-15793630(-) m6A CDS       25683224//25456834//25412662//24981863//25569111//26404942//22608085//22575960 chr12:15793728-15793729(-) m6A CDS       25683224//25456834//25412662//24981863//25569111//22608085 chr12:15793813-15793814(-) m6A CDS       25683224//25412662//24981863//25569111//22608085 chr12:15793965-15793966(-) m6A CDS       25683224//25412662//24981863//25569111//22608085 chr12:15809851-15809852(-) m6A CDS       25683224//24981863//25569111//22608085 chr12:15809888-15809889(-) m6A CDS       25683224//24981863//25569111//22608085 chr12:15815282-15815283(-) m6A CDS       25683224//24981863//25569111 chr12:15815342-15815343(-) m6A CDS       25683224//25412662//24981863//25569111//22608085 chr12:15815349-15815350(-) m6A CDS       25683224//25456834//25412662//24981863//25569111//22608085 chr12:15815375-15815376(-) m6A CDS       25683224//25456834//25412662//24981863//25569111//22608085 chr12:15815439-15815440(-) m6A CDS       25683224//25456834//25412662//24981863//25569111//22608085 chr12:15815444-15815445(-) m6A CDS       25683224//25456834//25412662//24981863//25569111//22608085 chr12:15815495-15815496(-) m6A CDS       25683224//24981863//25569111//22608085 chr12:15815690-15815691(-) m6A 5'UTR       25683224//25412662//24981863//25569111 chr12:15815743-15815744(-) m6A 5'UTR       25683224//25412662//24981863//25569111 chr12:15815802-15815803(-) m6A 5'UTR       25683224//25412662//24981863//25569111//22608085 chr12:15815808-15815809(-) m6A 5'UTR       25683224//25412662//24981863//25569111//22608085 chr12:15815926-15815927(-) m6A 5'UTR//exon       25683224//25412662//24981863//25569111 chr12:15815935-15815936(-) m6A 5'UTR//exon       25683224//25412662//24981863//25569111 chr12:15816013-15816014(-) m6A 5'UTR//exon       25683224//24981863//25569111 chr12:15816123-15816124(-) m6A 5'UTR//exon       25683224//24981863//25569111 chr12:15816172-15816173(-) m6A 5'UTR//exon       25683224//24981863//25569111 chr12:15816446-15816447(-) m6A 5'UTR//exon       25683224//25412662 chr12:15816521-15816522(-) m6A 5'UTR//exon       25683224//25412662 chr12:15816556-15816557(-) m6A 5'UTR//exon       25683224//24981863//25569111 chr12:15816592-15816593(-) m6A 5'UTR//exon       25683224//24981863//25569111 chr12:15816627-15816628(-) m6A 5'UTR//intron       25683224//24981863//25569111 chr12:15816859-15816860(-) m6A exon       25683224//24981863

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	mmu-miR-199a-3p	Exosome Conditioned medium of E13 SMG     28041903 Exosome B6 BMDCs     22031862
	Trib2	Nucleus Neuroblastoma cell line (N2A)     22406755

Interaction Network (The top 100 interactions):

Interactor1: mmu-miR-199a-3p
Interactor2: Trib2

Evidence Support:

Weak-Evidence	MiRNA microarray
Prediction-Evidence	Targetscan
Support Database	ViRBase

References:

PMID	20643939	Target region	None
Source	ViRBase	Interactor1 expression	Upregulation
Tissue or cell line	NIH3T3 cells	Interactor2 expression	Downregulation
Description	All of the regulated genes in Fig. 5B are down-regulated by miR-199a-3p mimic and up-regulated by miR-199a-3p inhibitor compared with the negative transfection control, with the exception of ITGA6, which is only up-regulated by the inhibitor (Dataset S3).