Detail

Basic Information:

VIRBase ID:

HHID00076442

Virus:

Murid betaherpesvirus 1

Host:

Mus musculus

Confidence Score:

0.5711

Interaction Type:

Host-Host interaction

Predicted Binding:

*It may take a few minutes to display results.

Interactor Information:

	Interactor1	Interactor2
Symbol	mmu-miR-199a-3p	Enpp3
miRBase Accession/Entrez ID	MIMAT0000230	209558
Organism	Mus musculus	Mus musculus
Category	miRNA	mRNA
Alias	-	AI876438//CD203c

RNA Modification:

Resource

Symbol

ModificationPosition

Type

Genomic Context

PMID

RMBase

Enpp3

chr10:24793619-24793620(-)	m6A	CDS	25412662
chr10:24795786-24795787(-)	m6A	CDS	25412662
chr10:24795804-24795805(-)	m6A	CDS	25412662
chr10:24826201-24826202(-)	m6A	CDS	25683224//25412662
chr10:24826213-24826214(-)	m6A	CDS	25683224//25412662
chr10:24826257-24826258(-)	m6A	CDS	25412662
chr10:24831734-24831735(-)	m6A	CDS	25412662
chr10:24831743-24831744(-)	m6A	CDS	25412662
chr10:24831752-24831753(-)	m6A	CDS	25412662
chr10:24831758-24831759(-)	m6A	CDS	25412662
chr10:24836046-24836047(-)	m6A	CDS	25569111
chr10:24836095-24836096(-)	m6A	5'UTR	25569111

RNA Localization:

Resource

Symbol

Subcellular Localization

Tissue or Cell Line

PMID

RNALocate

mmu-miR-199a-3p

Exosome	Conditioned medium of E13 SMG	28041903
Exosome	B6 BMDCs	22031862

Enpp3

Nucleus

Neuroblastoma cell line (N2A)

22406755

Interaction Network (The top 100 interactions):

Interactor1: mmu-miR-199a-3p

Interactor2: Enpp3

Evidence Support:

Weak-Evidence	MiRNA microarray
Prediction-Evidence	Targetscan
Support Database	ViRBase

References:

PMID	20643939	Target region	None
Source	ViRBase	Interactor1 expression	Upregulation
Tissue or cell line	NIH3T3 cells	Interactor2 expression	Downregulation
Description	All of the regulated genes in Fig. 5B are down-regulated by miR-199a-3p mimic and up-regulated by miR-199a-3p inhibitor compared with the negative transfection control, with the exception of ITGA6, which is only up-regulated by the inhibitor (Dataset S3).