Basic Information:

  VIRBase ID:  

HHID00076440

  Virus:  

Murid betaherpesvirus 1

  Host:  

Mus musculus

  Confidence Score:  

0.5711

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      mmu-miR-199a-3p:  MIMAT0000230          Tmem199:  NM_199199     

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Interactor Information:

	Interactor1	Interactor2
Symbol	mmu-miR-199a-3p	Tmem199
miRBase Accession/Entrez ID	MIMAT0000230	195040
Organism	Mus musculus	Mus musculus
Category	miRNA	mRNA
Alias	-	AI316787//AI848469//R74819

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	Tmem199	chr11:78507297-78507298(-) m6A 3'UTR//exon       26404942 chr11:78507320-78507321(-) m6A 3'UTR//exon       26404942 chr11:78507341-78507342(-) m6A 3'UTR//exon       26404942 chr11:78507361-78507362(-) m6A 3'UTR//exon       26404942 chr11:78507376-78507377(-) m6A 3'UTR//exon       26404942 chr11:78507399-78507400(-) m6A 3'UTR//exon       24981863//26404942 chr11:78507498-78507499(-) m6A 3'UTR//exon       24981863//25569111 chr11:78507507-78507508(-) m6A 3'UTR//exon       24981863//25569111 chr11:78507523-78507524(-) m6A 3'UTR//exon       24981863//25569111 chr11:78507591-78507592(-) m6A 3'UTR//exon       24981863//25569111 chr11:78507643-78507644(-) m6A 3'UTR//exon       24981863//25569111 chr11:78507662-78507663(-) m6A 3'UTR//exon       24981863//25569111 chr11:78507724-78507725(-) m6A CDS//exon       24981863//25569111//22608085 chr11:78507757-78507758(-) m6A CDS//exon       24981863//25569111//22608085 chr11:78511957-78511958(-) m6A CDS//exon       25412662//24981863//25569111 chr11:78511984-78511985(-) m6A CDS//exon       25412662//24981863//25569111 chr11:78512047-78512048(-) m6A CDS//exon       25412662//24981863//25456834//25569111

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	mmu-miR-199a-3p	Exosome Conditioned medium of E13 SMG     28041903 Exosome B6 BMDCs     22031862

Interaction Network (The top 100 interactions):

Interactor1: mmu-miR-199a-3p
Interactor2: Tmem199

Evidence Support:

Weak-Evidence	MiRNA microarray
Prediction-Evidence	Targetscan
Support Database	ViRBase

References:

PMID	20643939	Target region	None
Source	ViRBase	Interactor1 expression	Upregulation
Tissue or cell line	NIH3T3 cells	Interactor2 expression	Downregulation
Description	All of the regulated genes in Fig. 5B are down-regulated by miR-199a-3p mimic and up-regulated by miR-199a-3p inhibitor compared with the negative transfection control, with the exception of ITGA6, which is only up-regulated by the inhibitor (Dataset S3).