Basic Information:

  VIRBase ID:  

HHID00076439

  Virus:  

Murid betaherpesvirus 1

  Host:  

Mus musculus

  Confidence Score:  

0.5711

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      mmu-miR-199a-3p:  MIMAT0000230          Mcfd2:  NM_139295     

      *It may take a few minutes to display results.

Interactor Information:

	Interactor1	Interactor2
Symbol	mmu-miR-199a-3p	Mcfd2
miRBase Accession/Entrez ID	MIMAT0000230	193813
Organism	Mus musculus	Mus musculus
Category	miRNA	mRNA
Alias	-	1810021C21Rik//F5f8d//LM//Lman1ip//Sdnsf

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	Mcfd2	chr17:87254785-87254786(-) m6A 3'UTR       24981863//25569111 chr17:87254818-87254819(-) m6A 3'UTR       24981863//25569111//26404942 chr17:87254895-87254896(-) m6A 3'UTR       24981863//25569111//26404942 chr17:87254957-87254958(-) m6A 3'UTR       25569111//26404942 chr17:87255118-87255119(-) m6A 3'UTR       24981863//25569111//26404942//22575960 chr17:87255152-87255153(-) m6A 3'UTR       24981863//25569111//26404942//22575960 chr17:87255178-87255179(-) m6A 3'UTR       24981863//25569111//26404942//22575960 chr17:87255279-87255280(-) m6A 3'UTR       25569111//22608085//22575960 chr17:87255567-87255568(-) m6A 3'UTR       25456834//24981863//25569111//26404942//22608085//22575960 chr17:87255580-87255581(-) m6A 3'UTR       25683224//25456834//24981863//25569111//26404942//22608085//22575960 chr17:87255601-87255602(-) m6A 3'UTR       25683224//25456834//24981863//25569111//26404942//22608085//22575960 chr17:87255755-87255756(-) m6A 3'UTR       25683224//25456834//25412662//24981863//25569111//26404942//22608085//22575960 chr17:87255856-87255857(-) m6A 3'UTR       25683224//25456834//24981863//25569111//26404942//22608085//22575960 chr17:87255924-87255925(-) m6A 3'UTR       25456834//24981863//25569111//26404942//22575960 chr17:87255974-87255975(-) m6A CDS       25456834//24981863//25569111//26404942//22575960 chr17:87256774-87256775(-) m6A 3'UTR//intron       25569111 chr17:87258799-87258800(-) m6A 5'UTR//exon//intron       24981863//25569111 chr17:87265825-87265826(-) m6A 5'UTR//intron       24981863//25569111 chr17:87265920-87265921(-) m6A 5'UTR       24981863//25569111

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	mmu-miR-199a-3p	Exosome Conditioned medium of E13 SMG     28041903 Exosome B6 BMDCs     22031862
	Mcfd2	Nucleus Neuroblastoma cell line (N2A)     22406755 Nucleus Neuroblastoma cell line (N2A)     22406755

Interaction Network (The top 100 interactions):

Interactor1: mmu-miR-199a-3p
Interactor2: Mcfd2

Evidence Support:

Weak-Evidence	MiRNA microarray
Prediction-Evidence	Targetscan
Support Database	ViRBase

References:

PMID	20643939	Target region	None
Source	ViRBase	Interactor1 expression	Upregulation
Tissue or cell line	NIH3T3 cells	Interactor2 expression	Downregulation
Description	All of the regulated genes in Fig. 5B are down-regulated by miR-199a-3p mimic and up-regulated by miR-199a-3p inhibitor compared with the negative transfection control, with the exception of ITGA6, which is only up-regulated by the inhibitor (Dataset S3).