Basic Information:

  VIRBase ID:  

HHID00076434

  Virus:  

Murid betaherpesvirus 1

  Host:  

Mus musculus

  Confidence Score:  

0.5711

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      mmu-miR-199a-3p:  MIMAT0000230          Pgd:  NM_001356332     

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Interactor Information:

	Interactor1	Interactor2
Symbol	mmu-miR-199a-3p	Pgd
miRBase Accession/Entrez ID	MIMAT0000230	110208
Organism	Mus musculus	Mus musculus
Category	miRNA	mRNA
Alias	-	0610042A05Rik//AU019875//C78335

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	Pgd	chr4:149149997-149149998(-) m6A 3'UTR       25683224//24981863//25569111 chr4:149150005-149150006(-) m6A 3'UTR       25683224//24981863//25569111 chr4:149150142-149150143(-) m6A 3'UTR       25683224//25456834//24981863//25569111//26404942 chr4:149150147-149150148(-) m6A 3'UTR       25683224//25456834//24981863//25569111//26404942 chr4:149150159-149150160(-) m6A 3'UTR       25683224//25456834//24981863//25569111//26404942 chr4:149150316-149150317(-) m6A 3'UTR       25683224//25456834//25412662//24981863//25569111//22575960 chr4:149150379-149150380(-) m6A 3'UTR       25683224//25456834//25412662//24981863//25569111//22575960 chr4:149150384-149150385(-) m6A 3'UTR       25683224//25456834//25412662//24981863//25569111//22608085//22575960 chr4:149150465-149150466(-) m6A 3'UTR       25683224//25456834//25412662//24981863//25569111//22608085//22575960 chr4:149150504-149150505(-) m6A 3'UTR       25683224//25456834//24981863//25569111 chr4:149150530-149150531(-) m1A 3'UTR       26863196 chr4:149150607-149150608(-) m6A 3'UTR       25683224//25456834//24981863//25569111 chr4:149150715-149150716(-) m6A CDS       25683224//24981863//25456834//25569111//26404942 chr4:149150727-149150728(-) m6A CDS       25683224//24981863//25456834//25569111//26404942 chr4:149150862-149150863(-) m6A CDS       24981863//25569111//26404942 chr4:149150882-149150883(-) m6A CDS       24981863//25569111//26404942 chr4:149155198-149155199(-) m6A exon//intron       25412662 chr4:149155210-149155211(-) m6A exon//intron       25412662 chr4:149155268-149155269(-) m6A exon//intron       25412662 chr4:149156651-149156652(-) m6A CDS//exon       25683224//25412662 chr4:149156683-149156684(-) m6A CDS//exon       25683224//25412662 chr4:149156719-149156720(-) m6A CDS//exon       25683224//25412662 chr4:149156764-149156765(-) m6A CDS//exon       25683224//25412662 chr4:149156774-149156775(-) m6A CDS//exon       25683224//25412662 chr4:149156779-149156780(-) m6A CDS//exon       25683224//25412662 chr4:149158033-149158034(-) m6A CDS//exon       25683224//25412662//24981863 chr4:149158145-149158146(-) m6A exon//intron       25683224//25412662//24981863 chr4:149158194-149158195(-) m6A exon//intron       25683224//25412662 chr4:149160016-149160017(-) m6A exon//intron       25683224//25412662 chr4:149160073-149160074(-) m6A CDS//exon       25683224//25412662 chr4:149160081-149160082(-) m6A CDS//exon       25683224//25412662 chr4:149160438-149160439(-) m6A exon//intron       25412662 chr4:149160846-149160847(-) m6A CDS//exon       25683224//25412662 chr4:149160939-149160940(-) m6A CDS//exon       25683224//25412662 chr4:149161451-149161452(-) m6A exon//intron       25683224//25412662 chr4:149161479-149161480(-) m6A exon//intron       25683224//25412662 chr4:149165210-149165211(-) m6A CDS//exon       25569111 chr4:149166028-149166029(-) m6A CDS//exon       25683224//24981863//25456834//25569111 chr4:149166040-149166041(-) m6A CDS//exon       25683224//24981863//25456834//25569111 chr4:149166060-149166061(-) m6A CDS//exon       25683224//24981863//25456834//25569111 chr4:149166669-149166670(-) m6A 5'UTR//exon       25683224//24981863//25456834//25569111

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	mmu-miR-199a-3p	Exosome Conditioned medium of E13 SMG     28041903 Exosome B6 BMDCs     22031862

Interaction Network (The top 100 interactions):

Interactor1: mmu-miR-199a-3p
Interactor2: Pgd

Evidence Support:

Weak-Evidence	MiRNA microarray
Prediction-Evidence	Targetscan
Support Database	ViRBase

References:

PMID	20643939	Target region	None
Source	ViRBase	Interactor1 expression	Upregulation
Tissue or cell line	NIH3T3 cells	Interactor2 expression	Downregulation
Description	All of the regulated genes in Fig. 5B are down-regulated by miR-199a-3p mimic and up-regulated by miR-199a-3p inhibitor compared with the negative transfection control, with the exception of ITGA6, which is only up-regulated by the inhibitor (Dataset S3).