Basic Information:

  VIRBase ID:  

HHID00076431

  Virus:  

Murid betaherpesvirus 1

  Host:  

Mus musculus

  Confidence Score:  

0.5711

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      mmu-miR-199a-3p:  MIMAT0000230          Scamp1:  NM_001346609     

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Interactor Information:

	Interactor1	Interactor2
Symbol	mmu-miR-199a-3p	Scamp1
miRBase Accession/Entrez ID	MIMAT0000230	107767
Organism	Mus musculus	Mus musculus
Category	miRNA	mRNA
Alias	-	4930505M11Rik//AI415563//AW122395

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	Scamp1	chr13:94203097-94203098(-) m6A 3'UTR       24981863//22608085 chr13:94203568-94203569(-) m6A 3'UTR       24981863//22608085 chr13:94203617-94203618(-) m6A 3'UTR       24981863//22608085 chr13:94203629-94203630(-) m6A 3'UTR       24981863//22608085 chr13:94203850-94203851(-) m6A 3'UTR       24981863//22608085 chr13:94203859-94203860(-) m6A 3'UTR       24981863//25569111//22608085 chr13:94203914-94203915(-) m6A 3'UTR       24981863//25569111//22608085 chr13:94203965-94203966(-) m6A 3'UTR       24981863//25569111//26404942//22608085 chr13:94204072-94204073(-) m6A CDS       24981863//25569111//26404942//22608085 chr13:94204081-94204082(-) m6A CDS       24981863//25569111//26404942//22608085 chr13:94204154-94204155(-) m6A CDS       24981863//25569111//26404942//22608085 chr13:94232156-94232157(-) m6A CDS       24981863//22608085 chr13:94232177-94232178(-) m6A CDS       24981863//22608085 chr13:94233108-94233109(-) m6A CDS       24981863//22608085 chr13:94246472-94246473(-) m6A 5'UTR//intron       24981863 chr13:94246524-94246525(-) m6A 5'UTR//intron       24981863 chr13:94246541-94246542(-) m6A 5'UTR//intron       24981863 chr13:94253028-94253029(-) m6A 5'UTR//CDS       24981863

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	mmu-miR-199a-3p	Exosome Conditioned medium of E13 SMG     28041903 Exosome B6 BMDCs     22031862

Interaction Network (The top 100 interactions):

Interactor1: mmu-miR-199a-3p
Interactor2: Scamp1

Evidence Support:

Weak-Evidence	MiRNA microarray
Prediction-Evidence	Targetscan
Support Database	ViRBase

References:

PMID	20643939	Target region	None
Source	ViRBase	Interactor1 expression	Upregulation
Tissue or cell line	NIH3T3 cells	Interactor2 expression	Downregulation
Description	All of the regulated genes in Fig. 5B are down-regulated by miR-199a-3p mimic and up-regulated by miR-199a-3p inhibitor compared with the negative transfection control, with the exception of ITGA6, which is only up-regulated by the inhibitor (Dataset S3).