Basic Information:

  VIRBase ID:  

HHID00076430

  Virus:  

Murid betaherpesvirus 1

  Host:  

Mus musculus

  Confidence Score:  

0.5711

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      mmu-miR-199a-3p:  MIMAT0000230          Ankrd1:  NM_013468     

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Interactor Information:

	Interactor1	Interactor2
Symbol	mmu-miR-199a-3p	Ankrd1
miRBase Accession/Entrez ID	MIMAT0000230	107765
Organism	Mus musculus	Mus musculus
Category	miRNA	mRNA
Alias	-	Alrp//C//CARP//Crap//MA//MARP1

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	Ankrd1	chr19:36111973-36111974(-) m6A 3'UTR       24981863 chr19:36112040-36112041(-) m6A 3'UTR       25683224//25412662//24981863//25569111 chr19:36112071-36112072(-) m6A 3'UTR       25683224//25412662//24981863//25569111 chr19:36112219-36112220(-) m6A 3'UTR       25683224//24981863//25569111 chr19:36112406-36112407(-) m6A 3'UTR       25683224//24981863//25569111 chr19:36112449-36112450(-) m6A 3'UTR       24981863//25569111 chr19:36112470-36112471(-) m6A 3'UTR       24981863//25569111 chr19:36112697-36112698(-) m6A 3'UTR       24981863//25569111 chr19:36112728-36112729(-) m6A CDS       24981863//25569111 chr19:36112771-36112772(-) m6A CDS       24981863//25569111 chr19:36112807-36112808(-) m6A CDS       25569111 chr19:36114980-36114981(-) m6A CDS       25569111 chr19:36114995-36114996(-) m6A CDS       25569111 chr19:36115037-36115038(-) m6A CDS       25569111 chr19:36117855-36117856(-) m6A CDS       25683224//24981863 chr19:36117861-36117862(-) m6A CDS       25683224//24981863 chr19:36117894-36117895(-) m6A CDS       25683224//24981863 chr19:36117935-36117936(-) m6A CDS       25683224//24981863 chr19:36118237-36118238(-) m6A CDS       25683224//24981863 chr19:36118266-36118267(-) m6A CDS       25683224//24981863 chr19:36118313-36118314(-) m6A CDS       25683224//24981863 chr19:36118322-36118323(-) m6A CDS       25683224//24981863 chr19:36118342-36118343(-) m6A CDS       25683224//24981863//25569111 chr19:36118348-36118349(-) m6A CDS       25683224//24981863//25569111 chr19:36119233-36119234(-) m6A CDS       25683224//24981863//25569111 chr19:36119251-36119252(-) m6A CDS       25683224//24981863//25569111 chr19:36119286-36119287(-) m6A CDS       25683224//24981863//25569111 chr19:36119294-36119295(-) m6A CDS       25683224//24981863//25569111 chr19:36119381-36119382(-) m6A CDS       25683224//24981863//25569111 chr19:36119796-36119797(-) m6A 5'UTR       25683224//24981863//25569111 chr19:36119802-36119803(-) m6A 5'UTR       25683224//24981863//25569111

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	mmu-miR-199a-3p	Exosome Conditioned medium of E13 SMG     28041903 Exosome B6 BMDCs     22031862

Interaction Network (The top 100 interactions):

Interactor1: mmu-miR-199a-3p
Interactor2: Ankrd1

Evidence Support:

Weak-Evidence	MiRNA microarray
Prediction-Evidence	Targetscan
Support Database	ViRBase

References:

PMID	20643939	Target region	None
Source	ViRBase	Interactor1 expression	Upregulation
Tissue or cell line	NIH3T3 cells	Interactor2 expression	Downregulation
Description	All of the regulated genes in Fig. 5B are down-regulated by miR-199a-3p mimic and up-regulated by miR-199a-3p inhibitor compared with the negative transfection control, with the exception of ITGA6, which is only up-regulated by the inhibitor (Dataset S3).