Basic Information:

  VIRBase ID:  

HHID00076428

  Virus:  

Murid betaherpesvirus 1

  Host:  

Mus musculus

  Confidence Score:  

0.5711

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      mmu-miR-199a-3p:  MIMAT0000230          Oaf:  NM_178644     

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Interactor Information:

	Interactor1	Interactor2
Symbol	mmu-miR-199a-3p	Oaf
miRBase Accession/Entrez ID	MIMAT0000230	102644
Organism	Mus musculus	Mus musculus
Category	miRNA	mRNA
Alias	-	AL024221//D130038B21Rik//D9Ucl//D9Ucla1

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	Oaf	chr9:43221637-43221638(-) m6A 3'UTR       25412662 chr9:43221686-43221687(-) m6A 3'UTR       25412662 chr9:43221725-43221726(-) m6A 3'UTR       25412662 chr9:43221743-43221744(-) m6A 3'UTR       25412662 chr9:43221976-43221977(-) m6A 3'UTR       25683224//25456834//25412662//24981863//25569111//22608085//22575960 chr9:43222032-43222033(-) m6A 3'UTR       25683224//25456834//25412662//24981863//25569111//22608085//22575960 chr9:43222078-43222079(-) m6A 3'UTR       25683224//25456834//25412662//24981863//25569111//22608085//22575960 chr9:43222102-43222103(-) m6A 3'UTR       25683224//25456834//25412662//24981863//25569111//26404942//22575960 chr9:43222185-43222186(-) m6A 3'UTR       25683224//25456834//25412662//24981863//25569111//26404942//22575960 chr9:43222195-43222196(-) m6A 3'UTR       25683224//25456834//25412662//24981863//25569111//26404942//22575960 chr9:43222206-43222207(-) m6A 3'UTR       25683224//25456834//25412662//24981863//25569111//26404942//22575960 chr9:43222256-43222257(-) m6A 3'UTR       25683224//25412662//24981863//25569111//26404942//22575960 chr9:43222556-43222557(-) m6A 3'UTR       25683224//25456834//25412662//24981863//25569111//26404942//22608085//22575960 chr9:43222563-43222564(-) m6A 3'UTR       25683224//25456834//25412662//24981863//25569111//26404942//22608085//22575960 chr9:43222580-43222581(-) m6A CDS       25683224//25456834//25412662//24981863//25569111//26404942//22608085//22575960 chr9:43222795-43222796(-) m6A CDS       25683224//25456834//25412662//24981863//25569111//26404942//22608085//22575960 chr9:43222832-43222833(-) m6A CDS       25412662//24981863//25569111//26404942 chr9:43223905-43223906(-) m6A CDS       25412662//24981863//25569111//26404942 chr9:43224072-43224073(-) m6A CDS       25412662 chr9:43239348-43239349(-) m6A CDS       25683224//25412662//25569111 chr9:43239373-43239374(-) m6A CDS       25683224//25412662//25569111 chr9:43239385-43239386(-) m6A CDS       25683224//25412662//25569111 chr9:43239426-43239427(-) m6A CDS       25683224//25412662//25569111 chr9:43239624-43239625(-) m6A 5'UTR       25683224//25412662//24981863//25569111 chr9:43239642-43239643(-) m6A 5'UTR       25683224//25412662//24981863//25569111//22575960 chr9:43239647-43239648(-) m6A 5'UTR       25683224//25412662//24981863//25569111//22575960 chr9:43239665-43239666(-) m6A 5'UTR       25683224//25412662//24981863//25569111//22575960 chr9:43239700-43239701(-) m6A 5'UTR       25683224//25412662//24981863//25569111//22575960 chr9:43239755-43239756(-) m6A 5'UTR       25683224//25412662//24981863//25569111//22575960 chr9:43239780-43239781(-) m6A 5'UTR       25683224//25412662//24981863//25569111//22575960

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	mmu-miR-199a-3p	Exosome Conditioned medium of E13 SMG     28041903 Exosome B6 BMDCs     22031862

Interaction Network (The top 100 interactions):

Interactor1: mmu-miR-199a-3p
Interactor2: Oaf

Evidence Support:

Weak-Evidence	MiRNA microarray
Prediction-Evidence	Targetscan
Support Database	ViRBase

References:

PMID	20643939	Target region	None
Source	ViRBase	Interactor1 expression	Upregulation
Tissue or cell line	NIH3T3 cells	Interactor2 expression	Downregulation
Description	All of the regulated genes in Fig. 5B are down-regulated by miR-199a-3p mimic and up-regulated by miR-199a-3p inhibitor compared with the negative transfection control, with the exception of ITGA6, which is only up-regulated by the inhibitor (Dataset S3).