Basic Information:

  VIRBase ID:  

HHID00076417

  Virus:  

Murid betaherpesvirus 1

  Host:  

Mus musculus

  Confidence Score:  

0.5711

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      mmu-miR-199a-3p:  MIMAT0000230          Errfi1:  NM_133753     

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Interactor Information:

	Interactor1	Interactor2
Symbol	mmu-miR-199a-3p	Errfi1
miRBase Accession/Entrez ID	MIMAT0000230	74155
Organism	Mus musculus	Mus musculus
Category	miRNA	mRNA
Alias	-	1300002F13Rik//AI788755//Mig-//Mig-6//Mig6//R//RALT

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	Errfi1	chr4:150854081-150854082(+) m6A 5'UTR       25412662 chr4:150854090-150854091(+) m6A 5'UTR       25412662 chr4:150855231-150855232(+) m6A 5'UTR//exon//intron       25412662//24981863//25569111 chr4:150855533-150855534(+) m6A exon//intron       25412662 chr4:150865407-150865408(+) m6A CDS       22575960 chr4:150866424-150866425(+) m6A CDS       25683224//25456834//25412662//24981863//25569111//22608085//22575960 chr4:150866463-150866464(+) m6A CDS       25683224//25456834//25412662//24981863//25569111//22608085//22575960 chr4:150866594-150866595(+) m6A CDS       25683224//25456834//25412662//24981863//25569111//22608085//22575960 chr4:150866648-150866649(+) m6A CDS       25683224//25456834//25412662//24981863//25569111//26404942//22608085//22575960 chr4:150866654-150866655(+) m6A CDS       25683224//25456834//25412662//24981863//25569111//26404942//22608085//22575960 chr4:150866669-150866670(+) m6A CDS       25683224//25456834//25412662//24981863//25569111//26404942//22608085//22575960 chr4:150866801-150866802(+) m6A CDS       25683224//25456834//25412662//24981863//25569111//26404942//22608085//22575960 chr4:150866816-150866817(+) m6A CDS       25683224//25456834//25412662//24981863//25569111//26404942//22608085//22575960 chr4:150866822-150866823(+) m6A CDS       25683224//25456834//25412662//24981863//25569111//26404942//22608085//22575960 chr4:150866871-150866872(+) m6A CDS       25683224//25456834//25412662//24981863//25569111//26404942//22608085//22575960 chr4:150866948-150866949(+) m6A CDS       25683224//25456834//25412662//24981863//25569111//26404942//22608085//22575960 chr4:150867002-150867003(+) m6A CDS       25683224//25456834//25412662//24981863//25569111//26404942//22608085//22575960 chr4:150867081-150867082(+) m6A CDS       25683224//25456834//25412662//24981863//25569111//26404942//22608085//22575960 chr4:150867210-150867211(+) m6A CDS       25456834//24981863//25569111//26404942//22608085//22575960 chr4:150867326-150867327(+) m6A CDS       25456834//24981863//25569111//26404942//22608085//22575960 chr4:150867361-150867362(+) m6A CDS       25456834//24981863//25569111//26404942//22608085//22575960 chr4:150867474-150867475(+) m6A CDS       25456834//24981863//25569111//26404942//22608085//22575960 chr4:150867575-150867576(+) m6A 3'UTR       25683224//25456834//24981863//25569111//26404942//22608085//22575960 chr4:150867606-150867607(+) m6A 3'UTR       25683224//25456834//24981863//25569111//26404942//22575960 chr4:150867788-150867789(+) m6A 3'UTR       26404942 chr4:150867841-150867842(+) m6A 3'UTR       26404942 chr4:150867850-150867851(+) m6A 3'UTR       26404942 chr4:150867863-150867864(+) m6A 3'UTR       26404942 chr4:150868112-150868113(+) m6A 3'UTR       26404942 chr4:150868126-150868127(+) m6A 3'UTR       26404942//22608085 chr4:150868221-150868222(+) m6A 3'UTR       26404942//22608085 chr4:150868301-150868302(+) m6A 3'UTR       22608085 chr4:150868564-150868565(+) m6A 3'UTR       22575960 chr4:150868620-150868621(+) m6A 3'UTR       24981863//22575960 chr4:150868649-150868650(+) m6A 3'UTR       25456834//24981863//25569111//26404942//22575960 chr4:150868686-150868687(+) m6A 3'UTR       25456834//24981863//25569111//26404942//22575960 chr4:150868734-150868735(+) m6A 3'UTR       25456834//24981863//25569111//26404942//22575960 chr4:150868751-150868752(+) m6A 3'UTR       25456834//24981863//25569111//26404942//22575960 chr4:150868801-150868802(+) m6A 3'UTR       25456834//24981863//25569111//22575960

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	mmu-miR-199a-3p	Exosome Conditioned medium of E13 SMG     28041903 Exosome B6 BMDCs     22031862

Interaction Network (The top 100 interactions):

Interactor1: mmu-miR-199a-3p
Interactor2: Errfi1

Evidence Support:

Weak-Evidence	MiRNA microarray
Prediction-Evidence	Targetscan
Support Database	ViRBase

References:

PMID	20643939	Target region	None
Source	ViRBase	Interactor1 expression	Upregulation
Tissue or cell line	NIH3T3 cells	Interactor2 expression	Downregulation
Description	All of the regulated genes in Fig. 5B are down-regulated by miR-199a-3p mimic and up-regulated by miR-199a-3p inhibitor compared with the negative transfection control, with the exception of ITGA6, which is only up-regulated by the inhibitor (Dataset S3).