Basic Information:

  VIRBase ID:  

HHID00076416

  Virus:  

Murid betaherpesvirus 1

  Host:  

Mus musculus

  Confidence Score:  

0.5711

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      mmu-miR-199a-3p:  MIMAT0000230          Cep55:  NM_028293     

      *It may take a few minutes to display results.

Interactor Information:

	Interactor1	Interactor2
Symbol	mmu-miR-199a-3p	Cep55
miRBase Accession/Entrez ID	MIMAT0000230	74107
Organism	Mus musculus	Mus musculus
Category	miRNA	mRNA
Alias	-	1200008O12Rik//2700032M20Rik

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	Cep55	chr19:38055122-38055123(+) m6A 5'UTR//intron       25569111 chr19:38055152-38055153(+) m6A 5'UTR//intron       25569111//22608085 chr19:38055157-38055158(+) m6A 5'UTR//intron       25569111//22608085 chr19:38055198-38055199(+) m6A 5'UTR//intron       25569111//22608085 chr19:38055228-38055229(+) m6A 5'UTR//intron       25569111//22608085 chr19:38055250-38055251(+) m6A 5'UTR//intron       25569111 chr19:38055309-38055310(+) m6A 5'UTR//intron       25569111 chr19:38057419-38057420(+) m6A 5'UTR//intron       25569111 chr19:38057491-38057492(+) m6A 5'UTR//intron       25569111 chr19:38057538-38057539(+) m6A 5'UTR//intron       25569111 chr19:38057870-38057871(+) m6A CDS       24981863//25569111 chr19:38057914-38057915(+) m6A CDS       25683224//25456834//25412662//24981863//25569111 chr19:38057973-38057974(+) m6A CDS       25683224//25456834//25412662//24981863//25569111 chr19:38060138-38060139(+) m6A CDS       25683224//25456834//25412662//24981863//25569111 chr19:38060154-38060155(+) m6A CDS       25683224//25456834//25412662//24981863//25569111 chr19:38060162-38060163(+) m6A CDS       25683224//25456834//25412662//24981863//25569111 chr19:38060218-38060219(+) m6A CDS       25683224//25456834//25412662//24981863//25569111 chr19:38060269-38060270(+) m6A CDS       25683224//25456834//25412662//24981863//25569111 chr19:38060285-38060286(+) m6A CDS       25683224//25456834//25412662//24981863//25569111 chr19:38060310-38060311(+) m6A CDS       25683224//25456834//25412662//24981863//25569111 chr19:38060319-38060320(+) m6A CDS       25683224//25456834//25412662//24981863//25569111 chr19:38062615-38062616(+) m6A CDS       25683224//25456834//25412662//24981863//25569111 chr19:38069092-38069093(+) m6A CDS       25456834//25412662//24981863//25569111 chr19:38069175-38069176(+) m6A CDS       24981863//25569111 chr19:38069181-38069182(+) m6A CDS       24981863//25569111 chr19:38069739-38069740(+) m6A CDS       25412662//24981863//25569111 chr19:38069789-38069790(+) m6A CDS       25412662//24981863 chr19:38069825-38069826(+) m6A CDS       25412662//24981863 chr19:38069846-38069847(+) m6A CDS       25412662//24981863 chr19:38071847-38071848(+) m6A CDS       24981863 chr19:38073350-38073351(+) m6A CDS       24981863 chr19:38073463-38073464(+) m6A CDS       24981863 chr19:38073595-38073596(+) m6A 3'UTR       25569111 chr19:38073739-38073740(+) m6A 3'UTR       25569111 chr19:38073800-38073801(+) m6A 3'UTR       25569111 chr19:38073853-38073854(+) m6A 3'UTR       25569111

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	mmu-miR-199a-3p	Exosome Conditioned medium of E13 SMG     28041903 Exosome B6 BMDCs     22031862
	Cep55	Nucleus Neuroblastoma cell line (N2A)     22406755

Interaction Network (The top 100 interactions):

Interactor1: mmu-miR-199a-3p
Interactor2: Cep55

Evidence Support:

Weak-Evidence	MiRNA microarray
Prediction-Evidence	Targetscan
Support Database	ViRBase

References:

PMID	20643939	Target region	None
Source	ViRBase	Interactor1 expression	Upregulation
Tissue or cell line	NIH3T3 cells	Interactor2 expression	Downregulation
Description	All of the regulated genes in Fig. 5B are down-regulated by miR-199a-3p mimic and up-regulated by miR-199a-3p inhibitor compared with the negative transfection control, with the exception of ITGA6, which is only up-regulated by the inhibitor (Dataset S3).