Basic Information:

  VIRBase ID:  

HHID00076364

  Virus:  

Murid betaherpesvirus 1

  Host:  

Mus musculus

  Confidence Score:  

0.5711

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      mmu-miR-199a-3p:  MIMAT0000230          Dusp14:  NM_019819     

      *It may take a few minutes to display results.

Interactor Information:

	Interactor1	Interactor2
Symbol	mmu-miR-199a-3p	Dusp14
miRBase Accession/Entrez ID	MIMAT0000230	56405
Organism	Mus musculus	Mus musculus
Category	miRNA	mRNA
Alias	-	1110014C10Rik//2310042C07Rik//D11Ertd395//D11Ertd395e//Mkp//MKP-L//Mkp6

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	Dusp14	chr11:84048687-84048688(-) m6A CDS       25683224//25456834//24981863//25569111//22608085 chr11:84048734-84048735(-) m6A CDS       25683224//25456834//24981863//25569111//22608085 chr11:84048952-84048953(-) m6A CDS       25683224//25456834//24981863//25569111//22608085 chr11:84049145-84049146(-) m6A CDS       25683224//25456834//25412662//24981863//25569111//22608085 chr11:84049179-84049180(-) m6A CDS       25683224//25412662//24981863//25569111//22608085 chr11:84049270-84049271(-) m6A 5'UTR       25683224//25412662//24981863//25569111 chr11:84050865-84050866(-) m6A 5'UTR       25683224//25412662//24981863//25569111 chr11:84050880-84050881(-) m6A 5'UTR       25683224//25412662//24981863//25569111 chr11:84067007-84067008(-) m6A 5'UTR//intron       25412662//24981863//25569111 chr11:84068304-84068305(-) m6A 5'UTR//intron       25412662//24981863//25569111 chr11:84068521-84068522(-) m6A 5'UTR       24981863

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	mmu-miR-199a-3p	Exosome Conditioned medium of E13 SMG     28041903 Exosome B6 BMDCs     22031862

Interaction Network (The top 100 interactions):

Interactor1: mmu-miR-199a-3p
Interactor2: Dusp14

Evidence Support:

Weak-Evidence	MiRNA microarray
Prediction-Evidence	Targetscan
Support Database	ViRBase

References:

PMID	20643939	Target region	None
Source	ViRBase	Interactor1 expression	Upregulation
Tissue or cell line	NIH3T3 cells	Interactor2 expression	Downregulation
Description	All of the regulated genes in Fig. 5B are down-regulated by miR-199a-3p mimic and up-regulated by miR-199a-3p inhibitor compared with the negative transfection control, with the exception of ITGA6, which is only up-regulated by the inhibitor (Dataset S3).