Basic Information:

  VIRBase ID:  

HHID00076361

  Virus:  

Murid betaherpesvirus 1

  Host:  

Mus musculus

  Confidence Score:  

0.5711

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      mmu-miR-199a-3p:  MIMAT0000230          Uchl5:  NM_001159866     

      *It may take a few minutes to display results.

Interactor Information:

	Interactor1	Interactor2
Symbol	mmu-miR-199a-3p	Uchl5
miRBase Accession/Entrez ID	MIMAT0000230	56207
Organism	Mus musculus	Mus musculus
Category	miRNA	mRNA
Alias	-	5830413B11Rik//Uch37

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	Uchl5	chr1:143777397-143777398(+) m6A 5'UTR//exon       24981863//25569111 chr1:143777723-143777724(+) m6A intron       25412662//24981863//25569111//22608085 chr1:143777730-143777731(+) m6A intron       25412662//24981863//25569111//22608085 chr1:143777736-143777737(+) m6A intron       25412662//24981863//25569111//22608085 chr1:143777947-143777948(+) m6A intron       25456834//24981863//25569111//22608085 chr1:143777976-143777977(+) m6A intron       25456834//24981863//25569111//22608085 chr1:143778010-143778011(+) m6A intron       25456834//24981863//25569111//22608085 chr1:143778192-143778193(+) m6A intron       24981863//25456834//22608085 chr1:143778981-143778982(+) m6A intron       22608085 chr1:143780774-143780775(+) m6A intron       24981863 chr1:143780821-143780822(+) m6A intron       24981863 chr1:143780916-143780917(+) m6A intron       24981863 chr1:143783684-143783685(+) m6A exon//intron       24981863 chr1:143783696-143783697(+) m6A exon//intron       24981863 chr1:143786194-143786195(+) Y CDS//exon       26075521 chr1:143794707-143794708(+) m6A CDS//exon       22608085 chr1:143794775-143794776(+) m6A CDS//exon       24981863 chr1:143797047-143797048(+) m6A exon//intron       25412662//24981863 chr1:143798456-143798457(+) m6A CDS       25412662//24981863 chr1:143798480-143798481(+) m6A CDS       25412662//24981863 chr1:143799925-143799926(+) m6A CDS       25412662//24981863 chr1:143799987-143799988(+) m6A CDS       25412662//24981863 chr1:143802191-143802192(+) m6A CDS       - chr1:143803010-143803011(+) m6A 3'UTR//intron       - chr1:143803023-143803024(+) m6A 3'UTR//intron       - chr1:143803049-143803050(+) m6A 3'UTR//intron       - chr1:143803064-143803065(+) m6A 3'UTR//intron       25412662//24981863 chr1:143806694-143806695(+) m6A 3'UTR//CDS       25412662//24981863//22608085 chr1:143806719-143806720(+) m6A 3'UTR//CDS       25412662//24981863//22608085 chr1:143806736-143806737(+) Y 3'UTR//exon       26075521 chr1:143806775-143806776(+) m6A 3'UTR       25412662//24981863//25456834//25569111//22608085 chr1:143806794-143806795(+) m6A 3'UTR       25412662//24981863//25456834//25569111//22608085 chr1:143806801-143806802(+) m6A 3'UTR       25412662//24981863//25456834//25569111//22608085

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	mmu-miR-199a-3p	Exosome Conditioned medium of E13 SMG     28041903 Exosome B6 BMDCs     22031862
	Uchl5	Nucleus Neuroblastoma cell line (N2A)     22406755

Interaction Network (The top 100 interactions):

Interactor1: mmu-miR-199a-3p
Interactor2: Uchl5

Evidence Support:

Weak-Evidence	MiRNA microarray
Prediction-Evidence	Targetscan
Support Database	ViRBase

References:

PMID	20643939	Target region	None
Source	ViRBase	Interactor1 expression	Upregulation
Tissue or cell line	NIH3T3 cells	Interactor2 expression	Downregulation
Description	All of the regulated genes in Fig. 5B are down-regulated by miR-199a-3p mimic and up-regulated by miR-199a-3p inhibitor compared with the negative transfection control, with the exception of ITGA6, which is only up-regulated by the inhibitor (Dataset S3).