Basic Information:

  VIRBase ID:  

HHID00076295

  Virus:  

Murid betaherpesvirus 1

  Host:  

Mus musculus

  Confidence Score:  

0.5711

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      mmu-miR-199a-3p:  MIMAT0000230          Serpine1:  NM_008871     

      *It may take a few minutes to display results.

Interactor Information:

	Interactor1	Interactor2
Symbol	mmu-miR-199a-3p	Serpine1
miRBase Accession/Entrez ID	MIMAT0000230	18787
Organism	Mus musculus	Mus musculus
Category	miRNA	mRNA
Alias	-	P//PA//PAI-1//PAI1//Pl//Planh1

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	Serpine1	chr5:137062689-137062690(-) m6A 3'UTR       24981863//25569111 chr5:137062899-137062900(-) m6A 3'UTR       25683224//25456834//25412662//24981863//25569111//22575960 chr5:137062936-137062937(-) m6A 3'UTR       25683224//25456834//25412662//24981863//25569111//22575960 chr5:137062944-137062945(-) m6A 3'UTR       25683224//25456834//25412662//24981863//25569111//22575960 chr5:137063011-137063012(-) m6A 3'UTR       25683224//25456834//24981863//25569111//22575960 chr5:137063018-137063019(-) m6A 3'UTR       25683224//25456834//24981863//25569111//22575960 chr5:137063091-137063092(-) m6A 3'UTR       25683224//25456834//24981863//25569111//22575960 chr5:137063118-137063119(-) m6A 3'UTR       25683224//25456834//24981863//25569111 chr5:137063140-137063141(-) m6A 3'UTR       25683224//25456834//24981863//25569111 chr5:137063208-137063209(-) m6A CDS       25456834//24981863//25569111 chr5:137063518-137063519(-) m6A CDS       25569111 chr5:137069374-137069375(-) m6A CDS       24981863//25569111 chr5:137069382-137069383(-) m6A CDS       25569111 chr5:137069393-137069394(-) m6A CDS       25569111 chr5:137069443-137069444(-) m6A CDS       25569111 chr5:137069488-137069489(-) m6A CDS       25569111 chr5:137070190-137070191(-) m6A exon//intron       25569111 chr5:137070892-137070893(-) m6A exon//intron       25412662 chr5:137070963-137070964(-) m6A exon//intron       25412662 chr5:137070975-137070976(-) m6A exon//intron       25412662//25569111 chr5:137071074-137071075(-) m6A CDS//exon       25569111 chr5:137071148-137071149(-) m6A CDS//exon       25569111 chr5:137072219-137072220(-) m6A 5'UTR//exon       24981863//25569111

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	mmu-miR-199a-3p	Exosome Conditioned medium of E13 SMG     28041903 Exosome B6 BMDCs     22031862

Interaction Network (The top 100 interactions):

Interactor1: mmu-miR-199a-3p
Interactor2: Serpine1

Evidence Support:

Weak-Evidence	MiRNA microarray
Prediction-Evidence	Targetscan
Support Database	ViRBase

References:

PMID	20643939	Target region	None
Source	ViRBase	Interactor1 expression	Upregulation
Tissue or cell line	NIH3T3 cells	Interactor2 expression	Downregulation
Description	All of the regulated genes in Fig. 5B are down-regulated by miR-199a-3p mimic and up-regulated by miR-199a-3p inhibitor compared with the negative transfection control, with the exception of ITGA6, which is only up-regulated by the inhibitor (Dataset S3).