Basic Information:

  VIRBase ID:  

HHID00076234

  Virus:  

Murid betaherpesvirus 1

  Host:  

Mus musculus

  Confidence Score:  

0.5711

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      mmu-miR-199a-3p:  MIMAT0000230          Cmas:  NM_009908     

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Interactor Information:

	Interactor1	Interactor2
Symbol	mmu-miR-199a-3p	Cmas
miRBase Accession/Entrez ID	MIMAT0000230	12764
Organism	Mus musculus	Mus musculus
Category	miRNA	mRNA
Alias	-	AW208911//CMPNeu5Ac//D6Bwg0250e

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	Cmas	chr6:142756950-142756951(+) m6A CDS       25412662//25569111//22608085 chr6:142767909-142767910(+) m6A 3'UTR//CDS//intron       24981863//22608085 chr6:142770001-142770002(+) m6A exon//intron       24981863 chr6:142770016-142770017(+) m6A exon//intron       24981863 chr6:142770043-142770044(+) m6A exon//intron       25683224 chr6:142770082-142770083(+) m6A exon//intron       25683224 chr6:142770580-142770581(+) m6A 3'UTR//CDS//exon       24981863//22608085 chr6:142771263-142771264(+) m6A 3'UTR//CDS//exon       22608085 chr6:142772172-142772173(+) m6A 3'UTR//CDS       22608085 chr6:142772180-142772181(+) m6A 3'UTR//CDS       22608085 chr6:142772636-142772637(+) m6A 3'UTR//intron       25683224//24981863//25569111 chr6:142772817-142772818(+) m6A 3'UTR//intron       25683224//25456834//24981863//25569111 chr6:142772826-142772827(+) m6A 3'UTR//intron       25683224//25456834//24981863//25569111 chr6:142772895-142772896(+) m6A 3'UTR//intron       25683224//25456834//24981863//25569111 chr6:142772978-142772979(+) m6A 3'UTR//intron       25683224//24981863//25569111 chr6:142773099-142773100(+) m6A 3'UTR//intron       25683224//25456834//24981863//25569111 chr6:142773105-142773106(+) m6A 3'UTR//intron       25683224//25456834//24981863//25569111 chr6:142773186-142773187(+) m6A 3'UTR//intron       25683224//25456834//24981863//25569111 chr6:142773316-142773317(+) m6A 3'UTR//intron       25683224//25456834//24981863//25569111 chr6:142773340-142773341(+) m6A 3'UTR//intron       25683224//25456834//24981863//25569111 chr6:142773365-142773366(+) m6A 3'UTR//intron       25683224//25456834//24981863//25569111 chr6:142773401-142773402(+) m6A 3'UTR//intron       24981863//25569111 chr6:142774364-142774365(+) m6A 3'UTR//intron       25683224 chr6:142774397-142774398(+) m6A 3'UTR//intron       25683224//24981863//25569111 chr6:142774441-142774442(+) m6A 3'UTR//intron       25683224//25412662//24981863//25569111 chr6:142774549-142774550(+) m6A 3'UTR//intron       25683224//25412662//24981863//25569111

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	mmu-miR-199a-3p	Exosome Conditioned medium of E13 SMG     28041903 Exosome B6 BMDCs     22031862
	Cmas	Exosome Mast cells     17486113

Interaction Network (The top 100 interactions):

Interactor1: mmu-miR-199a-3p
Interactor2: Cmas

Evidence Support:

Weak-Evidence	MiRNA microarray
Prediction-Evidence	Targetscan
Support Database	ViRBase

References:

PMID	20643939	Target region	None
Source	ViRBase	Interactor1 expression	Upregulation
Tissue or cell line	NIH3T3 cells	Interactor2 expression	Downregulation
Description	All of the regulated genes in Fig. 5B are down-regulated by miR-199a-3p mimic and up-regulated by miR-199a-3p inhibitor compared with the negative transfection control, with the exception of ITGA6, which is only up-regulated by the inhibitor (Dataset S3).