Basic Information:

  VIRBase ID:  

HHID00076228

  Virus:  

Murid betaherpesvirus 1

  Host:  

Mus musculus

  Confidence Score:  

0.5711

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      mmu-miR-199a-3p:  MIMAT0000230          Cd2ap:  NM_009847     

      *It may take a few minutes to display results.

Interactor Information:

	Interactor1	Interactor2
Symbol	mmu-miR-199a-3p	Cd2ap
miRBase Accession/Entrez ID	MIMAT0000230	12488
Organism	Mus musculus	Mus musculus
Category	miRNA	mRNA
Alias	-	AL024079//C78928//Mets//METS-//METS-1//Mets1

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	Cd2ap	chr17:42793387-42793388(-) m6A 3'UTR       24981863 chr17:42793416-42793417(-) m6A 3'UTR       24981863 chr17:42793469-42793470(-) m6A 3'UTR       24981863 chr17:42795438-42795439(-) Y 3'UTR//exon       26075521 chr17:42795898-42795899(-) Y 3'UTR//exon       26075521 chr17:42795972-42795973(-) m6A 3'UTR       24981863 chr17:42796119-42796120(-) m6A 3'UTR       25683224//25412662//24981863//25456834//25569111 chr17:42796229-42796230(-) m6A 3'UTR       25683224//25456834//25412662//24981863//25569111//22608085//22575960 chr17:42796235-42796236(-) m6A 3'UTR       25683224//25456834//25412662//24981863//25569111//22608085//22575960 chr17:42796271-42796272(-) m6A 3'UTR       25683224//25456834//25412662//24981863//25569111//22608085//22575960 chr17:42796291-42796292(-) m6A 3'UTR       25683224//25456834//25412662//24981863//25569111//22608085 chr17:42796316-42796317(-) m6A 3'UTR       25683224//25456834//25412662//24981863//25569111//22608085 chr17:42798651-42798652(-) m6A CDS       25683224//25456834//24981863//25569111 chr17:42805218-42805219(-) m6A CDS       25569111 chr17:42805269-42805270(-) m6A CDS       25569111//22608085 chr17:42807993-42807994(-) m6A CDS       22608085 chr17:42808781-42808782(-) m6A CDS       - chr17:42808806-42808807(-) m6A CDS       - chr17:42816557-42816558(-) m6A CDS       25683224//25412662//24981863 chr17:42816566-42816567(-) m6A CDS       25683224//25412662//24981863 chr17:42816572-42816573(-) m6A CDS       25683224//25412662//24981863 chr17:42822373-42822374(-) m6A CDS       25683224//24981863 chr17:42822382-42822383(-) m6A CDS       25683224//24981863 chr17:42824480-42824481(-) m6A CDS       25683224//24981863 chr17:42824491-42824492(-) m6A CDS       25683224//24981863 chr17:42824545-42824546(-) m6A CDS       24981863 chr17:42824574-42824575(-) m6A CDS       24981863 chr17:42825878-42825879(-) m6A CDS       24981863 chr17:42825892-42825893(-) m6A CDS       24981863//22608085 chr17:42825913-42825914(-) m6A CDS       24981863//22608085 chr17:42826305-42826306(-) m6A CDS       24981863//22608085 chr17:42829993-42829994(-) m6A CDS       22608085 chr17:42830049-42830050(-) m6A CDS       22608085 chr17:42834188-42834189(-) m6A CDS       - chr17:42834226-42834227(-) m6A CDS       24981863 chr17:42834240-42834241(-) m6A CDS       24981863 chr17:42834253-42834254(-) m6A CDS       24981863 chr17:42834260-42834261(-) m6A CDS       24981863 chr17:42838743-42838744(-) m6A CDS       24981863 chr17:42852439-42852440(-) m6A CDS       24981863

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	mmu-miR-199a-3p	Exosome Conditioned medium of E13 SMG     28041903 Exosome B6 BMDCs     22031862

Interaction Network (The top 100 interactions):

Interactor1: mmu-miR-199a-3p
Interactor2: Cd2ap

Evidence Support:

Weak-Evidence	MiRNA microarray
Prediction-Evidence	Targetscan
Support Database	ViRBase

References:

PMID	20643939	Target region	None
Source	ViRBase	Interactor1 expression	Upregulation
Tissue or cell line	NIH3T3 cells	Interactor2 expression	Downregulation
Description	All of the regulated genes in Fig. 5B are down-regulated by miR-199a-3p mimic and up-regulated by miR-199a-3p inhibitor compared with the negative transfection control, with the exception of ITGA6, which is only up-regulated by the inhibitor (Dataset S3).