Detail Information

Basic Information:


  VIRBase ID:  

HHID00076080

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-101-2-5p:           TMEM123:      

      *It may take a few minutes to display results.

Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-101-2-5p TMEM123
miRBase
Accession/Entrez ID		 MIMAT0037312 114908
Organism Homo sapiens Homo sapiens
Category miRNA mRNA
Alias - KCT3//PORIMIN//PORMIN

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-101-2-5p
rs1189997653 chr9:4850323    C/G
rs1411860402 chr9:4850328    G/C
rs1472339708 chr9:4850325    G/A
rs374692878 chr9:4850308    T/C
rs752365347 chr9:4850320    G/C
rs758036961 chr9:4850324    C/T
rs777507775 chr9:4850326    A/G
rs570832031 chr9:4850310    G/A
rs570832031 chr9:4850310    G/T
rs766953168 chr9:4850309    C/T
rs779213487 chr9:4850315    T/C
rs894878476 chr9:4850314    A/G

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR TMEM123
chr11:102296483(-) A-I      intronic
chr11:102296423(-) A-I      intronic
chr11:102296412(-) A-I      intronic
chr11:102296490(-) A-I      intronic
chr11:102296488(-) A-I      intronic
chr11:102277381(-) A-I      intronic
chr11:102306289(-) A-I      intronic
chr11:102296484(-) A-I      intronic
chr11:102296485(-) A-I      intronic
chr11:102308175(-) A-I      intronic
chr11:102306962(-) A-I      intronic
chr11:102298335(-) A-I      intronic
chr11:102298457(-) A-I      intronic
chr11:102299161(-) A-I      intronic
chr11:102299171(-) A-I      intronic
chr11:102298362(-) A-I      intronic
chr11:102299234(-) A-I      intronic
chr11:102298388(-) A-I      intronic
chr11:102296429(-) A-I      intronic
chr11:102298486(-) A-I      intronic
chr11:102299170(-) A-I      intronic
chr11:102298572(-) A-I      intronic
chr11:102299181(-) A-I      intronic
chr11:102299317(-) A-I      intronic
chr11:102275918(-) A-I      intronic
chr11:102308136(-) A-I      intronic
chr11:102299085(-) A-I      intronic
chr11:102296507(-) A-I      intronic
chr11:102299131(-) A-I      intronic
chr11:102308908(-) A-I      intronic
chr11:102296533(-) A-I      intronic
chr11:102299068(-) A-I      intronic
chr11:102298313(-) A-I      intronic
chr11:102306961(-) A-I      intronic
chr11:102296537(-) A-I      intronic
chr11:102306048(-) A-I      intronic
chr11:102296517(-) A-I      intronic
chr11:102306225(-) A-I      intronic
chr11:102306022(-) A-I      intronic
chr11:102291692(-) A-I      intronic
chr11:102296393(-) A-I      intronic
chr11:102277453(-) A-I      intronic
chr11:102298566(-) A-I      intronic
chr11:102305115(-) A-I      intronic
chr11:102308870(-) A-I      intronic
chr11:102296479(-) A-I      intronic
chr11:102307069(-) A-I      intronic
chr11:102308137(-) A-I      intronic
chr11:102291609(-) A-I      intronic
chr11:102308153(-) A-I      intronic
chr11:102296532(-) A-I      intronic
chr11:102296453(-) A-I      intronic
chr11:102306298(-) A-I      intronic
chr11:102307058(-) A-I      intronic
chr11:102308916(-) A-I      intronic
chr11:102307032(-) A-I      intronic
chr11:102298447(-) A-I      intronic
chr11:102275409(-) A-I      intronic
chr11:102298383(-) A-I      intronic
chr11:102308961(-) A-I      intronic
chr11:102298396(-) A-I      intronic
chr11:102296417(-) A-I      intronic
chr11:102296463(-) A-I      intronic
chr11:102273997(-) A-I      intronic
chr11:102308957(-) A-I      intronic
chr11:102296591(-) A-I      intronic
chr11:102308106(-) A-I      intronic
chr11:102298402(-) A-I      intronic
chr11:102299311(-) A-I      intronic
chr11:102306267(-) A-I      intronic
chr11:102305119(-) A-I      intronic
chr11:102308183(-) A-I      intronic
chr11:102299233(-) A-I      intronic
chr11:102305111(-) A-I      intronic
chr11:102308818(-) A-I      intronic
chr11:102305167(-) A-I      intronic
chr11:102305107(-) A-I      intronic
Resource Symbol Editing Position Change SeqReg exReg PMID
DARNED TMEM123
chr11:102304997(-) A-I intron -    21960545
chr11:102306203(-) A-I intron -    21960545
chr11:102306225(-) A-I intron -    21960545
chr11:102306262(-) A-I intron -    21960545
chr11:102306267(-) A-I intron -    21960545
chr11:102306351(-) A-I intron -    21960545
chr11:102306352(-) A-I intron -    21960545
chr11:102305107(-) A-G intron -    22484847
chr11:102305111(-) A-G intron -    22484847
chr11:102305119(-) A-G intron -    22484847
chr11:102305167(-) A-G intron -    22484847
chr11:102306022(-) A-G intron -    22484847
chr11:102306048(-) A-G intron -    22484847
chr11:102306225(-) A-G intron -    22484847
chr11:102306298(-) A-G intron -    22484847
chr11:102296307(-) G-A intron -    22484847

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase TMEM123
chr11:102267156-102267157(-) Y 3'UTR       26075521
chr11:102267301-102267302(-) m6A 3'UTR       26404942
chr11:102267320-102267321(-) Y 3'UTR       26075521
chr11:102268026-102268027(-) m6A 3'UTR       26404942
chr11:102268059-102268060(-) m6A 3'UTR       26404942
chr11:102268375-102268376(-) m6A 3'UTR       26404942
chr11:102268539-102268540(-) m6A 3'UTR       26404942
chr11:102268581-102268582(-) m6A 3'UTR       26404942
chr11:102268606-102268607(-) m6A 3'UTR       26404942
chr11:102268630-102268631(-) m6A 3'UTR       26404942
chr11:102268654-102268655(-) m6A 3'UTR       26404942
chr11:102268700-102268701(-) m6A 3'UTR       26404942
chr11:102269615-102269616(-) m6A CDS       26404942
chr11:102272273-102272274(-) m6A CDS       26404942
chr11:102272723-102272724(-) m6A CDS//exon       24981863//26404942//27773535
chr11:102272742-102272743(-) m6A CDS//exon       24981863//26404942//27773535
chr11:102272824-102272825(-) m6A CDS//exon       24981863//26404942//27773535
chr11:102272855-102272856(-) m6A 5'UTR//CDS//exon       24981863//26404942//27773535
chr11:102272878-102272879(-) m6A 5'UTR//CDS//exon       24981863//26404942//27773535
chr11:102272898-102272899(-) m6A 5'UTR//CDS//exon       24981863//26404942//27773535
chr11:102272934-102272935(-) m6A 5'UTR//CDS//exon       24981863//26404942//27773535
chr11:102319005-102319006(-) m6A 5'UTR//intron       27773535
chr11:102319051-102319052(-) m6A 5'UTR//intron       27773535
chr11:102323088-102323089(-) m6A 5'UTR//intron       27371828//27773536
chr11:102323348-102323349(-) m6A CDS//intron       24284625//25456834//24981863//28052920//27371828//27773536//22575960
chr11:102323356-102323357(-) m6A 5'UTR//intron       24284625//25456834//24981863//28052920//27371828//27773536//22575960
chr11:102323592-102323593(-) m6A 5'UTR//intron       24981863//27371828//27773536
chr11:102323690-102323691(-) m6A 5'UTR//intron       24981863//27371828//27773536
chr11:102323698-102323699(-) m6A 5'UTR//intron       24981863//27371828//27773536

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate TMEM123
Chromatin K562 cells     -
Cytosol HCC cell line (HepG2)|HeLa-S3 cells     -
Exosome Blood     -
Insoluble cytoplasm HCC cell line (HepG2)     -
Membrane HCC cell line (HepG2)     -
Nucleolus K562 cells     -
Nucleoplasm K562 cells     -
Nucleus HCC cell line (HepG2)|K562 cells     -

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-101-2-5p
Interactor2: TMEM123

Evidence Support:


Weak-Evidence PAR-CLIP
Support Database ViRBase

References:


PMID 22291592 Target region CDS
Source ViRBase Interactor1 expression None
Tissue or cell line EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells Interactor2 expression None
Description We identified 7, 827 miRNA-interaction sites in 3, 492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.

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