Basic Information:

  VIRBase ID:  

HHID00076062

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-101-2-5p:  MIMAT0037312          TGIF2:  NM_001199515     

      *It may take a few minutes to display results.

Interactor Information:

	Interactor1	Interactor2
Symbol	hsa-miR-101-2-5p	TGIF2
miRBase Accession/Entrez ID	MIMAT0037312	60436
Organism	Homo sapiens	Homo sapiens
Category	miRNA	mRNA
Alias	-	-

ncRNA SNP information:

Resource	Symbol	SNP ID	SNP Position	Ref/Alt
miRNASNP-v3	hsa-miR-101-2-5p	rs1189997653 chr9:4850323    C/G rs1411860402 chr9:4850328    G/C rs1472339708 chr9:4850325    G/A rs374692878 chr9:4850308    T/C rs752365347 chr9:4850320    G/C rs758036961 chr9:4850324    C/T rs777507775 chr9:4850326    A/G rs570832031 chr9:4850310    G/A rs570832031 chr9:4850310    G/T rs766953168 chr9:4850309    C/T rs779213487 chr9:4850315    T/C rs894878476 chr9:4850314    A/G

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	TGIF2	chr20:35205293(+) A-I      intronic chr20:35205996(+) A-I      intronic chr20:35206002(+) A-I      intronic chr20:35206045(+) A-I      intronic chr20:35209102(+) A-I      intronic chr20:35209116(+) A-I      intronic chr20:35213523(+) A-I      intronic chr20:35216414(+) A-I      intronic chr20:35209098(+) A-I      intronic chr20:35205220(+) A-I      intronic chr20:35205189(+) A-I      intronic chr20:35219285(+) A-I      intronic chr20:35205225(+) A-I      intronic chr20:35205244(+) A-I      intronic chr20:35205247(+) A-I      intronic chr20:35205270(+) A-I      intronic chr20:35216430(+) A-I      intronic chr20:35213669(+) A-I      intronic chr20:35211930(+) A-I      intronic chr20:35216455(+) A-I      intronic chr20:35216843(+) A-I      intronic chr20:35216921(+) A-I      intronic chr20:35217852(+) A-I      intronic chr20:35217895(+) A-I      intronic chr20:35217896(+) A-I      intronic chr20:35217979(+) A-I      intronic chr20:35217981(+) A-I      intronic chr20:35218005(+) A-I      intronic chr20:35218016(+) A-I      intronic chr20:35218017(+) A-I      intronic chr20:35218018(+) A-I      intronic chr20:35218056(+) A-I      intronic chr20:35218068(+) A-I      intronic chr20:35218159(+) A-I      intronic chr20:35218161(+) A-I      intronic chr20:35218209(+) A-I      intronic chr20:35218235(+) A-I      intronic chr20:35218237(+) A-I      intronic chr20:35218253(+) A-I      intronic chr20:35218621(+) A-I      intronic chr20:35218634(+) A-I      intronic chr20:35218774(+) A-I      intronic chr20:35218786(+) A-I      intronic chr20:35218812(+) A-I      intronic chr20:35218846(+) A-I      intronic chr20:35219018(+) A-I      intronic chr20:35219035(+) A-I      intronic chr20:35219047(+) A-I      intronic chr20:35219085(+) A-I      intronic chr20:35219097(+) A-I      intronic chr20:35219107(+) A-I      intronic chr20:35219171(+) A-I      intronic chr20:35212123(+) A-I      intronic chr20:35212124(+) A-I      intronic chr20:35212180(+) A-I      intronic chr20:35212359(+) A-I      intronic chr20:35212363(+) A-I      intronic chr20:35212382(+) A-I      intronic chr20:35212390(+) A-I      intronic chr20:35213043(+) A-I      intronic chr20:35213053(+) A-I      intronic chr20:35213223(+) A-I      intronic chr20:35213328(+) A-I      intronic chr20:35213336(+) A-I      intronic chr20:35213393(+) A-I      intronic chr20:35213404(+) A-I      intronic chr20:35213429(+) A-I      intronic chr20:35213438(+) A-I      intronic chr20:35213441(+) A-I      intronic chr20:35213485(+) A-I      intronic chr20:35213651(+) A-I      intronic chr20:35213662(+) A-I      intronic chr20:35213781(+) A-I      intronic chr20:35213817(+) A-I      intronic chr20:35211917(+) A-I      intronic chr20:35214873(+) A-I      intronic chr20:35214883(+) A-I      intronic chr20:35214912(+) A-I      intronic chr20:35214945(+) A-I      intronic chr20:35214946(+) A-I      intronic chr20:35215018(+) A-I      intronic chr20:35215019(+) A-I      intronic chr20:35215026(+) A-I      intronic chr20:35215039(+) A-I      intronic chr20:35216190(+) A-I      intronic chr20:35216204(+) A-I      intronic chr20:35216212(+) A-I      intronic chr20:35216284(+) A-I      intronic chr20:35216291(+) A-I      intronic chr20:35216303(+) A-I      intronic chr20:35216393(+) A-I      intronic chr20:35216419(+) A-I      intronic chr20:35205232(+) A-I      intronic chr20:35205269(+) A-I      intronic chr20:35205317(+) A-I      intronic chr20:35205343(+) A-I      intronic chr20:35206609(+) A-I      intronic chr20:35206637(+) A-I      intronic chr20:35206662(+) A-I      intronic chr20:35206706(+) A-I      intronic chr20:35206710(+) A-I      intronic chr20:35206727(+) A-I      intronic chr20:35206728(+) A-I      intronic chr20:35206750(+) A-I      intronic chr20:35208965(+) A-I      intronic chr20:35208978(+) A-I      intronic chr20:35208981(+) A-I      intronic chr20:35208986(+) A-I      intronic chr20:35209294(+) A-I      intronic chr20:35209295(+) A-I      intronic chr20:35209326(+) A-I      intronic chr20:35209344(+) A-I      intronic chr20:35209436(+) A-I      intronic chr20:35209442(+) A-I      intronic chr20:35210161(+) A-I      intronic chr20:35210384(+) A-I      intronic chr20:35210443(+) A-I      intronic chr20:35210453(+) A-I      intronic chr20:35210478(+) A-I      intronic chr20:35210480(+) A-I      intronic chr20:35210592(+) A-I      intronic chr20:35211786(+) A-I      intronic chr20:35211810(+) A-I      intronic chr20:35211836(+) A-I      intronic chr20:35211909(+) A-I      intronic chr20:35209357(+) A-I      intronic chr20:35218275(+) A-I      intronic chr20:35213823(+) A-I      intronic chr20:35214842(+) A-I      intronic chr20:35209475(+) A-I      intronic chr20:35212427(+) A-I      intronic chr20:35218057(+) A-I      intronic chr20:35210101(+) A-I      intronic chr20:35209409(+) A-I      intronic chr20:35212250(+) A-I      intronic chr20:35206757(+) A-I      intronic chr20:35209451(+) A-I      intronic chr20:35209415(+) A-I      intronic chr20:35211914(+) A-I      intronic chr20:35211800(+) A-I      intronic chr20:35207639(+) A-I      intronic chr20:35210136(+) A-I      intronic chr20:35211585(+) A-I      intronic chr20:35213344(+) A-I      intronic chr20:35218221(+) A-I      intronic chr20:35213199(+) A-I      intronic chr20:35212256(+) A-I      intronic chr20:35214978(+) A-I      intronic chr20:35205273(+) A-I      intronic chr20:35205234(+) A-I      intronic chr20:35206736(+) A-I      intronic chr20:35213755(+) A-I      intronic chr20:35213424(+) A-I      intronic chr20:35213139(+) A-I      intronic chr20:35213809(+) A-I      intronic chr20:35207614(+) A-I      intronic chr20:35206552(+) A-I      intronic chr20:35216292(+) A-I      intronic chr20:35213209(+) A-I      intronic chr20:35211584(+) A-I      intronic chr20:35209426(+) A-I      intronic chr20:35213645(+) A-I      intronic chr20:35219094(+) A-I      intronic chr20:35213479(+) A-I      intronic chr20:35217827(+) A-I      intronic chr20:35206731(+) A-I      intronic chr20:35218166(+) A-I      intronic chr20:35213736(+) A-I      intronic chr20:35213342(+) A-I      intronic chr20:35209352(+) A-I      intronic chr20:35210111(+) A-I      intronic chr20:35210589(+) A-I      intronic chr20:35213786(+) A-I      intronic chr20:35205212(+) A-I      intronic chr20:35218507(+) A-I      intronic chr20:35221303(+) A-I      3'UTR chr20:35221292(+) A-I      3'UTR chr20:35212422(+) A-I      intronic chr20:35210603(+) A-I      intronic chr20:35215055(+) A-I      intronic chr20:35205207(+) A-I      intronic chr20:35212241(+) A-I      intronic chr20:35206048(+) A-I      intronic chr20:35216388(+) A-I      intronic chr20:35213818(+) A-I      intronic chr20:35206688(+) A-I      intronic chr20:35217925(+) A-I      intronic chr20:35213768(+) A-I      intronic chr20:35216903(+) A-I      intronic chr20:35209092(+) A-I      intronic chr20:35216213(+) A-I      intronic chr20:35212235(+) A-I      intronic chr20:35206696(+) A-I      intronic chr20:35213079(+) A-I      intronic chr20:35211954(+) A-I      intronic chr20:35209082(+) A-I      intronic chr20:35206102(+) A-I      intronic chr20:35214922(+) A-I      intronic chr20:35206737(+) A-I      intronic chr20:35213527(+) A-I      intronic chr20:35210237(+) A-I      intronic chr20:35213050(+) A-I      intronic chr20:35211598(+) A-I      intronic chr20:35214977(+) A-I      intronic chr20:35210477(+) A-I      intronic chr20:35216898(+) A-I      intronic chr20:35211727(+) A-I      intronic chr20:35214848(+) A-I      intronic chr20:35219019(+) A-I      intronic chr20:35210112(+) A-I      intronic chr20:35216392(+) A-I      intronic chr20:35219037(+) A-I      intronic chr20:35210561(+) A-I      intronic chr20:35210211(+) A-I      intronic chr20:35216893(+) A-I      intronic chr20:35206613(+) A-I      intronic chr20:35213691(+) A-I      intronic chr20:35210419(+) A-I      intronic chr20:35210531(+) A-I      intronic chr20:35205330(+) A-I      intronic chr20:35212179(+) A-I      intronic chr20:35206766(+) A-I      intronic chr20:35218354(+) A-I      intronic chr20:35208953(+) A-I      intronic chr20:35214938(+) A-I      intronic chr20:35212377(+) A-I      intronic chr20:35213147(+) A-I      intronic chr20:35218123(+) A-I      intronic chr20:35219236(+) A-I      intronic chr20:35211464(+) A-I      intronic chr20:35218218(+) A-I      intronic chr20:35213414(+) A-I      intronic chr20:35218249(+) A-I      intronic chr20:35211762(+) A-I      intronic chr20:35209516(+) A-I      intronic chr20:35213493(+) A-I      intronic chr20:35213646(+) A-I      intronic chr20:35218595(+) A-I      intronic chr20:35216334(+) A-I      intronic chr20:35212343(+) A-I      intronic chr20:35217814(+) A-I      intronic chr20:35218840(+) A-I      intronic chr20:35214866(+) A-I      intronic chr20:35205305(+) A-I      intronic chr20:35207714(+) A-I      intronic chr20:35218116(+) A-I      intronic chr20:35213150(+) A-I      intronic chr20:35214942(+) A-I      intronic chr20:35205983(+) A-I      intronic chr20:35205208(+) A-I      intronic chr20:35210131(+) A-I      intronic chr20:35218471(+) A-I      intronic chr20:35206674(+) A-I      intronic chr20:35206591(+) A-I      intronic chr20:35209137(+) A-I      intronic chr20:35206741(+) A-I      intronic chr20:35216868(+) A-I      intronic chr20:35205888(+) A-I      intronic chr20:35218425(+) A-I      intronic chr20:35214864(+) A-I      intronic chr20:35213435(+) A-I      intronic chr20:35216342(+) A-I      intronic chr20:35216832(+) A-I      intronic chr20:35218488(+) A-I      intronic chr20:35211424(+) A-I      intronic chr20:35216872(+) A-I      intronic chr20:35205282(+) A-I      intronic chr20:35210267(+) A-I      intronic chr20:35204352(+) A-I      intronic chr20:35212450(+) A-I      intronic chr20:35206099(+) A-I      intronic chr20:35210270(+) A-I      intronic chr20:35213338(+) A-I      intronic chr20:35218281(+) A-I      intronic chr20:35208973(+) A-I      intronic chr20:35210132(+) A-I      intronic chr20:35218301(+) A-I      intronic chr20:35205291(+) A-I      intronic chr20:35210438(+) A-I      intronic chr20:35213423(+) A-I      intronic chr20:35213410(+) A-I      intronic chr20:35219224(+) A-I      intronic chr20:35206185(+) A-I      intronic chr20:35205626(+) A-I      intronic chr20:35213014(+) A-I      intronic chr20:35216412(+) A-I      intronic chr20:35217921(+) A-I      intronic chr20:35206614(+) A-I      intronic chr20:35206538(+) A-I      intronic chr20:35213124(+) A-I      intronic chr20:35213769(+) A-I      intronic chr20:35206765(+) A-I      intronic chr20:35218560(+) A-I      intronic chr20:35206639(+) A-I      intronic chr20:35212090(+) A-I      intronic chr20:35210491(+) A-I      intronic chr20:35213030(+) A-I      intronic chr20:35218226(+) A-I      intronic chr20:35214921(+) A-I      intronic chr20:35217876(+) A-I      intronic chr20:35217899(+) A-I      intronic chr20:35206756(+) A-I      intronic chr20:35206751(+) A-I      intronic chr20:35210468(+) A-I      intronic

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	TGIF2	chr20:35202127-35202128(+) m6A 5'UTR//intron       - chr20:35202986-35202987(+) m6A 5'UTR//intron       - chr20:35203007-35203008(+) m6A 5'UTR//intron       - chr20:35203012-35203013(+) m6A 5'UTR//intron       - chr20:35203030-35203031(+) m6A 5'UTR//intron       - chr20:35203233-35203234(+) m6A 5'UTR//intron       - chr20:35207184-35207185(+) m6A CDS       24284625 chr20:35207247-35207248(+) m6A CDS       24284625 chr20:35207280-35207281(+) m6A CDS       24284625 chr20:35207344-35207345(+) m6A CDS       24284625 chr20:35219355-35219356(+) m6A CDS//intron       24284625 chr20:35219379-35219380(+) m6A CDS//intron       24284625 chr20:35219653-35219654(+) m6A CDS//intron       24284625//24209618//25456834//24981863//27773535//22575960//22608085 chr20:35219691-35219692(+) m6A CDS//intron       24284625//24209618//25456834//24981863//27773535//22575960//22608085 chr20:35219700-35219701(+) m6A CDS//intron       24284625//24209618//25456834//24981863//27773535//22575960//22608085 chr20:35219775-35219776(+) m6A CDS//intron       24284625//24209618//25456834//24981863//26404942//22575960//22608085 chr20:35219932-35219933(+) m6A 3'UTR//CDS//intron       24284625//24209618//25456834//24981863//22608085 chr20:35220060-35220061(+) m6A 3'UTR       24284625//24209618//25456834//24981863//22608085 chr20:35220075-35220076(+) m6A 3'UTR       24284625//24209618//25456834//24981863//22608085 chr20:35220123-35220124(+) m6A 3'UTR       24284625//24209618//25456834//24981863//22608085 chr20:35220233-35220234(+) m6A 3'UTR       24284625//24209618//25456834//24981863//22608085 chr20:35220256-35220257(+) m6A 3'UTR       24284625//24209618//24981863//22608085 chr20:35220272-35220273(+) m6A 3'UTR       24284625//24981863//22608085 chr20:35220291-35220292(+) m6A 3'UTR       24284625//24981863//22608085 chr20:35220325-35220326(+) m6A 3'UTR       24284625//24981863//22608085 chr20:35220435-35220436(+) m6A 3'UTR       24284625//24981863//22608085 chr20:35220491-35220492(+) m6A 3'UTR       24981863//27773535//22608085 chr20:35220584-35220585(+) m6A 3'UTR       24209618//24981863//27773535//22608085 chr20:35220661-35220662(+) m6A 3'UTR       24209618//24981863//22608085 chr20:35220769-35220770(+) m6A 3'UTR       24981863 chr20:35220998-35220999(+) m6A 3'UTR       25456834 chr20:35221039-35221040(+) m6A 3'UTR       - chr20:35222070-35222071(+) Y 3'UTR       26075521

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	TGIF2	Cytoplasm Nasopharyngeal carcinoma cells     20498841 Exosome Blood     - Nucleolus K562 cells     - Nucleus Nasopharyngeal carcinoma cells     20498841

Interaction Network (The top 100 interactions):

Interactor1: hsa-miR-101-2-5p
Interactor2: TGIF2

Evidence Support:

Weak-Evidence	PAR-CLIP
Support Database	ViRBase

References:

PMID	22291592	Target region	3'UTR
Source	ViRBase	Interactor1 expression	None
Tissue or cell line	EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells	Interactor2 expression	None
Description	We identified 7, 827 miRNA-interaction sites in 3, 492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.