Detail Information

Basic Information:


  VIRBase ID:  

HHID00076050

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-101-2-5p:           LIN7C:      

      *It may take a few minutes to display results.

Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-101-2-5p LIN7C
miRBase
Accession/Entrez ID		 MIMAT0037312 55327
Organism Homo sapiens Homo sapiens
Category miRNA mRNA
Alias - LIN-7-C//LIN-7C//MALS-3//MALS3//VELI3

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-101-2-5p
rs1189997653 chr9:4850323    C/G
rs1411860402 chr9:4850328    G/C
rs1472339708 chr9:4850325    G/A
rs374692878 chr9:4850308    T/C
rs752365347 chr9:4850320    G/C
rs758036961 chr9:4850324    C/T
rs777507775 chr9:4850326    A/G
rs570832031 chr9:4850310    G/A
rs570832031 chr9:4850310    G/T
rs766953168 chr9:4850309    C/T
rs779213487 chr9:4850315    T/C
rs894878476 chr9:4850314    A/G

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR LIN7C
chr11:27524615(-) A-I      intronic
chr11:27525279(-) A-I      intronic
chr11:27525199(-) A-I      intronic
chr11:27525185(-) A-I      intronic
chr11:27526714(-) A-I      intronic
chr11:27525314(-) A-I      intronic
chr11:27525288(-) A-I      intronic
chr11:27525234(-) A-I      intronic
chr11:27525231(-) A-I      intronic
chr11:27525230(-) A-I      intronic
chr11:27526796(-) A-I      intronic
chr11:27526767(-) A-I      intronic
chr11:27525513(-) A-I      intronic
chr11:27525467(-) A-I      intronic
chr11:27525403(-) A-I      intronic
chr11:27525332(-) A-I      intronic
chr11:27525331(-) A-I      intronic
chr11:27516825(-) A-I      3'UTR
chr11:27525326(-) A-I      intronic
chr11:27525198(-) A-I      intronic
chr11:27525610(-) A-I      intronic
chr11:27525432(-) A-I      intronic
chr11:27525509(-) A-I      intronic
chr11:27524550(-) A-I      intronic
chr11:27517444(-) A-I      3'UTR

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase LIN7C
chr11:27520100-27520101(-) m6A 3'UTR       24981863//27773535
chr11:27520183-27520184(-) m6A 3'UTR       24284625//24981863//27773535//22608085
chr11:27520200-27520201(-) m6A CDS       24284625//24981863//27773535//27371828//22608085
chr11:27520315-27520316(-) m6A CDS       24284625//24209618//24981863//28052920//27773535//27371828//22608085
chr11:27520336-27520337(-) m6A CDS       24284625//24209618//24981863//27773535//27371828//22608085
chr11:27520953-27520954(-) m6A CDS       24284625//24209618//24981863//27773535//27371828//22608085
chr11:27521002-27521003(-) m6A CDS       24284625//24209618//24981863//27773535//27371828//22608085
chr11:27521007-27521008(-) m6A CDS       24209618//24981863//27773535//22608085
chr11:27521048-27521049(-) m6A CDS       24209618//27773535
chr11:27521082-27521083(-) m6A CDS       24209618//27773535
chr11:27523084-27523085(-) m6A CDS//intron       24209618//27773535
chr11:27523091-27523092(-) m6A CDS//intron       24209618//27773535
chr11:27523104-27523105(-) m6A CDS//intron       24209618//27773535
chr11:27523402-27523403(-) m6A CDS       24209618//24981863//27773535//22608085
chr11:27523435-27523436(-) m6A CDS       24209618//24981863//27773535//22608085
chr11:27528281-27528282(-) m6A CDS       24209618//24981863//27773535//22608085

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate LIN7C
Chromatin K562 cells     -
Cytosol Human myelogenous leukemia cell line (K-562)     21613539
Exosome Blood     -
Ribosome Colon cancer cells     24393600

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-101-2-5p
Interactor2: LIN7C

Evidence Support:


Weak-Evidence PAR-CLIP
Support Database ViRBase

References:


PMID 22291592 Target region 3'UTR
Source ViRBase Interactor1 expression None
Tissue or cell line EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells Interactor2 expression None
Description We identified 7, 827 miRNA-interaction sites in 3, 492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.

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