Basic Information:

  VIRBase ID:  

HHID00076042

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-101-2-5p:  MIMAT0037312          MFSD6:  NM_001375987     

      *It may take a few minutes to display results.

Interactor Information:

	Interactor1	Interactor2
Symbol	hsa-miR-101-2-5p	MFSD6
miRBase Accession/Entrez ID	MIMAT0037312	54842
Organism	Homo sapiens	Homo sapiens
Category	miRNA	mRNA
Alias	-	hMMR2//MMR2

ncRNA SNP information:

Resource	Symbol	SNP ID	SNP Position	Ref/Alt
miRNASNP-v3	hsa-miR-101-2-5p	rs1189997653 chr9:4850323    C/G rs1411860402 chr9:4850328    G/C rs1472339708 chr9:4850325    G/A rs374692878 chr9:4850308    T/C rs752365347 chr9:4850320    G/C rs758036961 chr9:4850324    C/T rs777507775 chr9:4850326    A/G rs570832031 chr9:4850310    G/A rs570832031 chr9:4850310    G/T rs766953168 chr9:4850309    C/T rs779213487 chr9:4850315    T/C rs894878476 chr9:4850314    A/G

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	MFSD6	chr2:191294234(+) A-I      intronic chr2:191294218(+) A-I      intronic chr2:191294263(+) A-I      intronic chr2:191294217(+) A-I      intronic chr2:191294237(+) A-I      intronic chr2:191297288(+) A-I      intronic chr2:191297396(+) A-I      intronic chr2:191298653(+) A-I      intronic chr2:191298670(+) A-I      intronic chr2:191299346(+) A-I      intronic chr2:191351890(+) A-I      intronic chr2:191351914(+) A-I      intronic chr2:191351970(+) A-I      intronic chr2:191351976(+) A-I      intronic chr2:191352804(+) A-I      intronic chr2:191275799(+) A-I      intronic chr2:191275623(+) A-I      intronic chr2:191297272(+) A-I      intronic chr2:191352812(+) A-I      intronic chr2:191275622(+) A-I      intronic chr2:191275617(+) A-I      intronic chr2:191298794(+) A-I      intronic chr2:191332219(+) A-I      intronic chr2:191333320(+) A-I      intronic chr2:191348414(+) A-I      intronic chr2:191298802(+) A-I      intronic chr2:191293673(+) A-I      intronic chr2:191280097(+) A-I      5'UTR chr2:191280130(+) A-I      5'UTR chr2:191298661(+) A-I      intronic chr2:191348400(+) A-I      intronic chr2:191352654(+) A-I      intronic chr2:191351828(+) A-I      intronic chr2:191298818(+) A-I      intronic chr2:191299369(+) A-I      intronic chr2:191333437(+) A-I      intronic chr2:191315439(+) A-I      intronic

Resource	Symbol	Editing Position	Change	SeqReg	exReg	PMID
DARNED	MFSD6	chr2:191280130(+) A-I exon 5'UTR    21960545 chr2:191280130(+) A-G exon 5'UTR    22484847 chr2:191298802(+) A-G intron -    22484847 chr2:191299369(+) A-G intron -    22484847 chr2:191315236(+) G-T intron -    22484847 chr2:191328325(+) T-C intron -    22484847 chr2:191328437(+) T-C intron -    22484847 chr2:191328464(+) T-C intron -    22484847 chr2:191328488(+) T-C intron -    22484847 chr2:191328505(+) T-C intron -    22484847 chr2:191332156(+) T-C intron -    22484847 chr2:191332176(+) T-C intron -    22484847 chr2:191332308(+) T-C intron -    22484847 chr2:191344883(+) T-C intron -    22484847 chr2:191348522(+) T-C intron -    22484847 chr2:191351828(+) A-G intron -    22484847 chr2:191351942(+) T-C intron -    22484847 chr2:191352632(+) T-A intron -    22484847 chr2:191352729(+) A-G intron -    22484847 chr2:191352865(+) G-T intron -    22484847

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	MFSD6	chr2:191300850-191300851(+) m6A CDS       24981863//26404942 chr2:191300856-191300857(+) m6A CDS       24981863//26404942 chr2:191300872-191300873(+) m6A CDS       24981863//26404942 chr2:191300890-191300891(+) m6A CDS       24209618//24981863//26404942 chr2:191300918-191300919(+) m6A CDS       24209618//24981863//26404942 chr2:191300931-191300932(+) m6A CDS       24209618//24981863//26404942 chr2:191300948-191300949(+) m6A CDS       24209618//24981863//26404942 chr2:191301036-191301037(+) m6A CDS       24981863//26404942 chr2:191301066-191301067(+) m6A CDS       24981863//26404942 chr2:191301131-191301132(+) m6A CDS       24981863 chr2:191301213-191301214(+) m6A CDS       24284625//24981863 chr2:191301353-191301354(+) m6A CDS       24284625//24209618//24981863//26404942//22575960//22608085 chr2:191301364-191301365(+) m6A CDS       24284625//24209618//24981863//26404942//22575960//22608085 chr2:191301383-191301384(+) m6A CDS       24284625//24209618//24981863//26404942//22575960//22608085 chr2:191301410-191301411(+) m6A CDS       24284625//24209618//25456834//24981863//26404942//22575960//22608085 chr2:191301416-191301417(+) m6A CDS       24284625//24209618//25456834//24981863//26404942//22575960//22608085 chr2:191301423-191301424(+) m6A CDS       24284625//24209618//25456834//24981863//26404942//22575960//22608085 chr2:191301442-191301443(+) m6A CDS       24284625//24209618//25456834//24981863//26404942//22575960//22608085 chr2:191301470-191301471(+) m6A CDS       24284625//24209618//25456834//24981863//26404942//22575960//22608085 chr2:191301482-191301483(+) m6A CDS       24284625//25456834//24981863//26404942//22575960//22608085 chr2:191301529-191301530(+) m6A CDS       24284625//25456834//24981863//26404942//22575960//22608085 chr2:191301995-191301996(+) m6A CDS       24284625//24981863//26404942//22608085 chr2:191302021-191302022(+) m6A CDS       24284625//24981863//26404942//22608085 chr2:191302064-191302065(+) m6A CDS       24284625//24209618//24981863//26404942//22608085 chr2:191302175-191302176(+) m6A CDS       24284625//24981863//22608085 chr2:191302186-191302187(+) m6A CDS       24284625//24981863//22608085 chr2:191364743-191364744(+) m6A CDS       24981863 chr2:191364800-191364801(+) m6A 3'UTR//CDS       24981863 chr2:191364822-191364823(+) m6A 3'UTR//CDS       24981863 chr2:191364860-191364861(+) m6A 3'UTR//CDS       24284625//25456834//24981863 chr2:191364885-191364886(+) m6A 3'UTR//CDS       24284625//25456834//24981863 chr2:191364937-191364938(+) m6A 3'UTR//CDS       24284625//25456834//24981863 chr2:191364995-191364996(+) m6A 3'UTR       24284625//25456834//24981863 chr2:191365072-191365073(+) m6A 3'UTR//intron       24284625//24981863 chr2:191365088-191365089(+) m6A 3'UTR//intron       24284625//24981863 chr2:191365132-191365133(+) m6A 3'UTR//intron       24981863 chr2:191365827-191365828(+) m6A 3'UTR//intron       27773535 chr2:191365991-191365992(+) m6A 3'UTR//intron       27773535 chr2:191366140-191366141(+) m6A 3'UTR//intron       24981863 chr2:191366204-191366205(+) m6A 3'UTR//intron       24981863 chr2:191366231-191366232(+) m6A 3'UTR//intron       24981863

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	MFSD6	Chromatin K562 cells     - Exosome Blood     - Nucleolus K562 cells     - Nucleoplasm K562 cells     - Nucleus HCC cell line (HepG2)     - Ribosome Colon cancer cells     24393600

Interaction Network (The top 100 interactions):

Interactor1: hsa-miR-101-2-5p
Interactor2: MFSD6

Evidence Support:

Weak-Evidence	PAR-CLIP
Support Database	ViRBase

References:

PMID	22291592	Target region	3'UTR
Source	ViRBase	Interactor1 expression	None
Tissue or cell line	EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells	Interactor2 expression	None
Description	We identified 7, 827 miRNA-interaction sites in 3, 492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.