Basic Information:

  VIRBase ID:  

HHID00076023

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-101-2-5p:  MIMAT0037312          PDS5B:  NM_015032     

      *It may take a few minutes to display results.

Interactor Information:

	Interactor1	Interactor2
Symbol	hsa-miR-101-2-5p	PDS5B
miRBase Accession/Entrez ID	MIMAT0037312	23047
Organism	Homo sapiens	Homo sapiens
Category	miRNA	mRNA
Alias	-	APRIN//AS3//CG008

ncRNA SNP information:

Resource	Symbol	SNP ID	SNP Position	Ref/Alt
miRNASNP-v3	hsa-miR-101-2-5p	rs1189997653 chr9:4850323    C/G rs1411860402 chr9:4850328    G/C rs1472339708 chr9:4850325    G/A rs374692878 chr9:4850308    T/C rs752365347 chr9:4850320    G/C rs758036961 chr9:4850324    C/T rs777507775 chr9:4850326    A/G rs570832031 chr9:4850310    G/A rs570832031 chr9:4850310    G/T rs766953168 chr9:4850309    C/T rs779213487 chr9:4850315    T/C rs894878476 chr9:4850314    A/G

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	PDS5B	chr13:33259892(+) A-I      intronic chr13:33235361(+) A-I      intronic chr13:33239927(+) A-I      intronic chr13:33194165(+) A-I      intronic chr13:33238164(+) A-I      intronic chr13:33238165(+) A-I      intronic chr13:33194145(+) A-I      intronic chr13:33194121(+) A-I      intronic chr13:33238198(+) A-I      intronic chr13:33238177(+) A-I      intronic chr13:33238227(+) A-I      intronic chr13:33239937(+) A-I      intronic chr13:33239946(+) A-I      intronic chr13:33239973(+) A-I      intronic chr13:33336066(+) A-I      intronic chr13:33239968(+) A-I      intronic chr13:33239969(+) A-I      intronic chr13:33259946(+) A-I      intronic chr13:33259919(+) A-I      intronic chr13:33194133(+) A-I      intronic chr13:33280083(+) A-I      intronic chr13:33171408(+) A-I      intronic chr13:33259977(+) A-I      intronic chr13:33240354(+) A-I      intronic chr13:33172421(+) A-I      intronic chr13:33172472(+) A-I      intronic chr13:33173874(+) A-I      intronic chr13:33200143(+) A-I      intronic chr13:33172629(+) A-I      intronic chr13:33174755(+) A-I      intronic chr13:33171206(+) A-I      intronic chr13:33172646(+) A-I      intronic chr13:33173500(+) A-I      intronic chr13:33173505(+) A-I      intronic chr13:33173625(+) A-I      intronic chr13:33214518(+) A-I      intronic chr13:33279948(+) A-I      intronic chr13:33235252(+) A-I      intronic chr13:33238978(+) A-I      intronic chr13:33173518(+) A-I      intronic chr13:33173541(+) A-I      intronic chr13:33235433(+) A-I      intronic chr13:33260828(+) A-I      intronic chr13:33173600(+) A-I      intronic chr13:33173931(+) A-I      intronic chr13:33173937(+) A-I      intronic chr13:33235447(+) A-I      intronic chr13:33173949(+) A-I      intronic chr13:33174012(+) A-I      intronic chr13:33174598(+) A-I      intronic chr13:33174791(+) A-I      intronic chr13:33172412(+) A-I      intronic chr13:33239658(+) A-I      intronic chr13:33174805(+) A-I      intronic chr13:33194125(+) A-I      intronic chr13:33199323(+) A-I      intronic chr13:33199328(+) A-I      intronic chr13:33199340(+) A-I      intronic chr13:33214445(+) A-I      intronic chr13:33194714(+) A-I      intronic chr13:33239457(+) A-I      intronic chr13:33202460(+) A-I      intronic chr13:33202474(+) A-I      intronic chr13:33239543(+) A-I      intronic chr13:33202484(+) A-I      intronic chr13:33202554(+) A-I      intronic chr13:33240287(+) A-I      intronic chr13:33202606(+) A-I      intronic chr13:33206991(+) A-I      intronic chr13:33207053(+) A-I      intronic chr13:33207085(+) A-I      intronic chr13:33214448(+) A-I      intronic chr13:33214513(+) A-I      intronic chr13:33214549(+) A-I      intronic chr13:33214564(+) A-I      intronic chr13:33214953(+) A-I      intronic chr13:33339903(+) A-I      intronic chr13:33214963(+) A-I      intronic chr13:33239551(+) A-I      intronic chr13:33239572(+) A-I      intronic chr13:33239605(+) A-I      intronic chr13:33214967(+) A-I      intronic chr13:33215029(+) A-I      intronic chr13:33235283(+) A-I      intronic chr13:33240282(+) A-I      intronic chr13:33235387(+) A-I      intronic chr13:33339841(+) A-I      intronic chr13:33259883(+) A-I      intronic chr13:33173470(+) A-I      intronic chr13:33215079(+) A-I      intronic chr13:33259897(+) A-I      intronic chr13:33239632(+) A-I      intronic chr13:33239545(+) A-I      intronic chr13:33235410(+) A-I      intronic chr13:33173905(+) A-I      intronic chr13:33260045(+) A-I      intronic chr13:33260012(+) A-I      intronic chr13:33260706(+) A-I      intronic chr13:33260711(+) A-I      intronic chr13:33202564(+) A-I      intronic chr13:33240359(+) A-I      intronic chr13:33279944(+) A-I      intronic chr13:33279952(+) A-I      intronic chr13:33171797(+) A-I      intronic chr13:33214646(+) A-I      intronic chr13:33280065(+) A-I      intronic chr13:33280153(+) A-I      intronic chr13:33280294(+) A-I      intronic chr13:33280336(+) A-I      intronic chr13:33280343(+) A-I      intronic chr13:33239647(+) A-I      intronic chr13:33171580(+) A-I      intronic chr13:33239473(+) A-I      intronic chr13:33259826(+) A-I      intronic chr13:33171708(+) A-I      intronic chr13:33171219(+) A-I      intronic chr13:33172694(+) A-I      intronic chr13:33215004(+) A-I      intronic chr13:33215008(+) A-I      intronic chr13:33239611(+) A-I      intronic chr13:33240493(+) A-I      intronic chr13:33172484(+) A-I      intronic chr13:33240347(+) A-I      intronic chr13:33214410(+) A-I      intronic chr13:33240424(+) A-I      intronic chr13:33240503(+) A-I      intronic chr13:33259182(+) A-I      intronic chr13:33215047(+) A-I      intronic chr13:33235427(+) A-I      intronic chr13:33260679(+) A-I      intronic chr13:33259945(+) A-I      intronic chr13:33170001(+) A-I      intronic chr13:33171877(+) A-I      intronic chr13:33171896(+) A-I      intronic chr13:33171905(+) A-I      intronic chr13:33172244(+) A-I      intronic chr13:33235493(+) A-I      intronic chr13:33172293(+) A-I      intronic chr13:33260720(+) A-I      intronic chr13:33173941(+) A-I      intronic chr13:33167623(+) A-I      intronic chr13:33174756(+) A-I      intronic chr13:33173864(+) A-I      intronic chr13:33173872(+) A-I      intronic chr13:33173873(+) A-I      intronic chr13:33214453(+) A-I      intronic chr13:33214584(+) A-I      intronic chr13:33167678(+) A-I      intronic chr13:33171707(+) A-I      intronic chr13:33171604(+) A-I      intronic chr13:33167643(+) A-I      intronic chr13:33171364(+) A-I      intronic chr13:33174669(+) A-I      intronic chr13:33171837(+) A-I      intronic chr13:33279993(+) A-I      intronic chr13:33194204(+) A-I      intronic chr13:33285269(+) A-I      intronic chr13:33260775(+) A-I      intronic chr13:33255705(+) A-I      intronic chr13:33172708(+) A-I      intronic chr13:33202591(+) A-I      intronic chr13:33214477(+) A-I      intronic chr13:33210180(+) A-I      intronic chr13:33208573(+) A-I      intronic chr13:33240311(+) A-I      intronic chr13:33294067(+) A-I      intronic chr13:33194036(+) A-I      intronic chr13:33172741(+) A-I      intronic chr13:33173796(+) A-I      intronic chr13:33167652(+) A-I      intronic chr13:33208555(+) A-I      intronic chr13:33239569(+) A-I      intronic chr13:33172349(+) A-I      intronic chr13:33171271(+) A-I      intronic chr13:33239579(+) A-I      intronic chr13:33174797(+) A-I      intronic chr13:33207087(+) A-I      intronic chr13:33238854(+) A-I      intronic chr13:33173530(+) A-I      intronic chr13:33279950(+) A-I      intronic chr13:33200142(+) A-I      intronic chr13:33285183(+) A-I      intronic chr13:33339856(+) A-I      intronic chr13:33208850(+) A-I      intronic chr13:33214550(+) A-I      intronic chr13:33285650(+) A-I      intronic chr13:33240237(+) A-I      intronic chr13:33258982(+) A-I      intronic chr13:33260011(+) A-I      intronic chr13:33171833(+) A-I      intronic chr13:33240415(+) A-I      intronic chr13:33200115(+) A-I      intronic chr13:33214484(+) A-I      intronic chr13:33173797(+) A-I      intronic chr13:33194644(+) A-I      intronic chr13:33235378(+) A-I      intronic chr13:33171691(+) A-I      intronic chr13:33194010(+) A-I      intronic chr13:33195524(+) A-I      intronic chr13:33206986(+) A-I      intronic chr13:33239710(+) A-I      intronic chr13:33202590(+) A-I      intronic chr13:33260901(+) A-I      intronic chr13:33280078(+) A-I      intronic chr13:33221520(+) A-I      intronic chr13:33208752(+) A-I      intronic chr13:33173543(+) A-I      intronic chr13:33279968(+) A-I      intronic chr13:33280288(+) A-I      intronic chr13:33173501(+) A-I      intronic chr13:33173536(+) A-I      intronic chr13:33171454(+) A-I      intronic chr13:33342684(+) A-I      intronic chr13:33324869(+) A-I      intronic chr13:33172346(+) A-I      intronic chr13:33171587(+) A-I      intronic chr13:33235414(+) A-I      intronic chr13:33239465(+) A-I      intronic chr13:33259909(+) A-I      intronic chr13:33172931(+) A-I      intronic chr13:33199307(+) A-I      intronic chr13:33239935(+) A-I      intronic chr13:33188534(+) A-I      intronic chr13:33194108(+) A-I      intronic chr13:33174037(+) A-I      intronic chr13:33195368(+) A-I      intronic chr13:33343181(+) A-I      intronic chr13:33171774(+) A-I      intronic chr13:33194013(+) A-I      intronic chr13:33226847(+) A-I      intronic chr13:33172693(+) A-I      intronic chr13:33194670(+) A-I      intronic chr13:33214525(+) A-I      intronic chr13:33202416(+) A-I      intronic chr13:33259881(+) A-I      intronic chr13:33226791(+) A-I      intronic chr13:33172659(+) A-I      intronic chr13:33260696(+) A-I      intronic chr13:33171863(+) A-I      intronic chr13:33171646(+) A-I      intronic chr13:33171602(+) A-I      intronic chr13:33171283(+) A-I      intronic chr13:33235460(+) A-I      intronic

Resource	Symbol	Editing Position	Change	SeqReg	exReg	PMID
DARNED	PDS5B	chr13:33240347(+) A-I intron -    21960545 chr13:33349235(+) C-T intron -    21725310 chr13:33221520(+) A-G intron -    22484847 chr13:33321691(+) C-T intron -    22484847

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	PDS5B	chr13:33222924-33222925(+) m6A CDS//exon       24209618//25456834//24981863 chr13:33222930-33222931(+) m6A CDS//exon       24209618//25456834//24981863 chr13:33344305-33344306(+) m6A CDS       24209618//24981863//27773535//22608085 chr13:33344353-33344354(+) m6A CDS//exon       24209618//24981863//27773535//22608085 chr13:33344359-33344360(+) m6A CDS//exon       24209618//24981863//27773535//22608085 chr13:33344416-33344417(+) m6A CDS//exon       24209618//24981863//27773535//22608085 chr13:33344473-33344474(+) m6A CDS//exon       24209618//24981863//27773535//22608085 chr13:33344518-33344519(+) m6A CDS//exon       24981863//27773535//22608085 chr13:33344561-33344562(+) m6A CDS//exon       24284625//24981863//27773535//22608085 chr13:33344593-33344594(+) m6A CDS//exon       24284625//24981863//27773535//27371828//22608085 chr13:33344629-33344630(+) m6A CDS//exon       24284625//24981863//27773535//27371828//22608085 chr13:33344647-33344648(+) m6A CDS//exon       24284625//24981863//27773535//27371828//22608085 chr13:33344665-33344666(+) m6A CDS//exon       24284625//24981863//27773535//27371828//22608085 chr13:33344857-33344858(+) m6A CDS//exon       24284625//24981863//27773535//22608085 chr13:33344924-33344925(+) m6A 3'UTR//exon//intron       24981863//27773535 chr13:33344965-33344966(+) m6A 3'UTR//exon//intron       24981863 chr13:33347344-33347345(+) m6A CDS//intron       24981863 chr13:33347432-33347433(+) m6A CDS//intron       24209618//24981863//27773535//22608085 chr13:33349190-33349191(+) m6A 3'UTR       24209618//24981863//27773535//22608085 chr13:33349294-33349295(+) m6A 3'UTR       24284625//24209618//25456834//24981863//26404942//27773535//22608085 chr13:33349309-33349310(+) m6A 3'UTR       24284625//24209618//25456834//24981863//26404942//27773535//22608085 chr13:33349317-33349318(+) m6A 3'UTR       24284625//24209618//25456834//24981863//26404942//27773535//22608085 chr13:33349424-33349425(+) m6A 3'UTR       24284625//24981863//22608085 chr13:33349437-33349438(+) m6A 3'UTR       24284625//24981863//22608085

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	PDS5B	Chromatin K562 cells     - Cytosol HCC cell line (HepG2)|K562 cells     - Exosome Blood     - Membrane K562 cells     - Nucleoplasm K562 cells     - Nucleus HCC cell line (HepG2)|HeLa-S3 cells|K562 cells     -

Interaction Network (The top 100 interactions):

Interactor1: hsa-miR-101-2-5p
Interactor2: PDS5B

Evidence Support:

Weak-Evidence	PAR-CLIP
Support Database	ViRBase

References:

PMID	22291592	Target region	3'UTR
Source	ViRBase	Interactor1 expression	None
Tissue or cell line	EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells	Interactor2 expression	None
Description	We identified 7, 827 miRNA-interaction sites in 3, 492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.