Detail Information

Basic Information:


  VIRBase ID:  

HHID00076020

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-101-2-5p:           CILK1:      

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Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-101-2-5p CILK1
miRBase
Accession/Entrez ID		 MIMAT0037312 22858
Organism Homo sapiens Homo sapiens
Category miRNA mRNA
Alias - ECO//EJM10//hICK//ICK//LCK2//MRK

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-101-2-5p
rs1189997653 chr9:4850323    C/G
rs1411860402 chr9:4850328    G/C
rs1472339708 chr9:4850325    G/A
rs374692878 chr9:4850308    T/C
rs752365347 chr9:4850320    G/C
rs758036961 chr9:4850324    C/T
rs777507775 chr9:4850326    A/G
rs570832031 chr9:4850310    G/A
rs570832031 chr9:4850310    G/T
rs766953168 chr9:4850309    C/T
rs779213487 chr9:4850315    T/C
rs894878476 chr9:4850314    A/G

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR CILK1
chr6:52892577(-) A-I      intronic
chr6:52914791(-) A-I      intronic
chr6:52892573(-) A-I      intronic
chr6:52886001(-) A-I      intronic
chr6:52914785(-) A-I      intronic
chr6:52892611(-) A-I      intronic
chr6:52892585(-) A-I      intronic
chr6:52886041(-) A-I      intronic
chr6:52886037(-) A-I      intronic
chr6:52886036(-) A-I      intronic
chr6:52886028(-) A-I      intronic
chr6:52872694(-) A-I      intronic
chr6:52914731(-) A-I      intronic
chr6:52868290(-) A-I      3'UTR
chr6:52868293(-) A-I      3'UTR
chr6:52868316(-) A-I      3'UTR
chr6:52868348(-) A-I      3'UTR
chr6:52868294(-) A-I      3'UTR
chr6:52873399(-) A-I      intronic
chr6:52873502(-) A-I      intronic
chr6:52889898(-) A-I      intronic
chr6:52868457(-) A-I      3'UTR
chr6:52896881(-) A-I      intronic
chr6:52873361(-) A-I      intronic
chr6:52873406(-) A-I      intronic
chr6:52873470(-) A-I      intronic
chr6:52914792(-) A-I      intronic
chr6:52872655(-) A-I      intronic
chr6:52887860(-) A-I      intronic
chr6:52885862(-) A-I      intronic
chr6:52893038(-) A-I      intronic
chr6:52873525(-) A-I      intronic

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate CILK1
Cytoplasm Nasopharyngeal carcinoma cells     20498841
Cytoplasm Nasopharyngeal carcinoma cells     20498841
Endoplasmic reticulum Human myelogenous leukemia cell line (K-562)     21613539
Exosome Blood     -
Insoluble cytoplasm HCC cell line (HepG2)     -
Membrane HCC cell line (HepG2)     -
Nucleus Nasopharyngeal carcinoma cells     20498841
Nucleus Nasopharyngeal carcinoma cells     20498841
Ribosome HEK-293 cells     22199352

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-101-2-5p
Interactor2: CILK1

Evidence Support:


Weak-Evidence PAR-CLIP
Support Database ViRBase

References:


PMID 22291592 Target region 3'UTR
Source ViRBase Interactor1 expression None
Tissue or cell line EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells Interactor2 expression None
Description We identified 7, 827 miRNA-interaction sites in 3, 492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.

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